The Lobby of Beijing International Convention Center , 3F

Registration

Keynote Forum
Time: July 18, 2009, Saturday, 9:35-11:35, Room 305

Session Chair:

Dr. Konglai Zhang, Professor, Department of Epidemiology, Peking Union Medical College, China

9:35-10:15

Title: A Novel Drug Target in Hepatitis B Virus Reverse Transcriptase: "Turn" of the Alpha-Helix-Clamp
Dr. Yumei Wen, Professor, Institute of Medical Microbiology, Fudan University, China

10:15-10:55

Title: The Recombinant Hepatitis B Vaccine
Dr. Pierre Tiollais, Professor, Institute Pasteur, France Academy of Sciences, France

10:55-11:35

Title: Novel Therapeutics of Flaviviruses
Dr. Yenliang Chen, Research Investigator II-Dengue, Novartis Institute for Tropical Diseases, Singapore

11:35-13:00

Luncheon

A (H1N1)
Time: July 18, 2009, Saturday, 13:30-16:20, Room 303

Session Chair:

Dr. Girish Kotwal, Adjunct Professor, UMass Medical School; President, InflaMed Inc. and Kotwal Bioconsulting, LLC, USA; Ex-director, WHO National Influenza Center, South Africa

Co-Chair:

Dr. Albert Cheunghoi Yu, CEO & Chairman, Hai Kang Life Corporation Limited, China

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: Winning The War Against Influenza Pandemics: The Demand for Innovative Diagnostic Tools
Dr. Albert Cheunghoi Yu, CEO & Chairman, Hai Kang Life Corporation Limited, China

14:00-14:25

Title: Role of Antiviral Enveloped Virus Neutralizing Compounds as Nutraceuticals and Immune Boosters in Prevention of Pandemics.
Dr. Girish Kotwal, Adjunct Professor, UMass Medical School; President, InflaMed Inc. and Kotwal Bioconsulting, LLC, USA; Ex-director, WHO National Influenza Center, South Africa

14:25-14:50

Title: Properties of Akacid, the Friendly Biocide
Dr. A. Georgopoulos, Professor, Medical University of Vienna, Austria

14:50-15:15

Title: Inactivation of Influenza A Virus on Copper versus Stainless Steel Surfaces
Dr. C. William Keevil, Professor, School of Biological Sciences, University of Southampton, UK

15:15-15:30

Coffee Break

15:30-15:55

Title: Real-time Clinical Research during an Epidemic Times
Dr. Paul S. Lietman, Professor, Pharmacology and Molecular Science and Pediatrics, The Johns Hopkins University School of Medicine, USA

15:55-16:20

Title: Nucleic Acids-based Rapid Diagnostics Methods in Combating Influenza: Strengths and Weaknesses
Dr. Miroslav Sip, Head, Department of Laboratory Methods and Medical Technology, Faculty of Health and Social Studies, University of south Bohemia, Czech Republic

Course 1: Cross Infection Control and Combination Therapy
Time: July 18, 2009, Saturday, 16:20-17:35, Room 303

Session Chair:

Dr. Hongzhou Lu, Executive Deputy Director, Shanghai Public Health Clinic Center, China

16:20-16:45

Title: Improved Method to Quantify Lamivudine, Stavudine, Zidovudine, Efavirenz and Nevirapine in Plasma of HIV-infected Patients
Dr. Hongzhou Lu, Executive Deputy Director, Shanghai Public Health Clinic Center, China

16:45-17:10

Title: Regulated Nuclear Transport of Viral Gene Products in Infection: A Therapeutic Target
Dr. Reena Ghildyal, Senior Research Fellow, Nuclear Signaling Group, Department of Biochemistry and Molecular Biology, Monash University, Australia

17:10-17:35

Title: Aspirin-An Immune Modulator in HIV Infection. Considerations to Adjuvant Aspirin Therapy
Dr. Grazyna Stanczuk, Professor, Department of Obstetrics and Gynaecology, Department of Immunology, Medical School University of Zimbabwe, Zimbabwe

Course 2: Molecular Diagnostics for Virus Infection
Time: July 20, 2009, Monday, 16:45-17:10, Room 311-C

16:45-17:10

Title: Identification of HPV Infected and Transformed Cells in Cytological and Histological Specimens
Dr. Tingchang Chang, Professor, Chang Gung University Medical College; Director, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Linkou Medical Center, Taiwan

Track1-1: Epidemiology and Virology
Time: July 18, 2009, Saturday, 13:30-17:10, Room 311-A

Session Chair:

Dr. Britt Gustafsson, Associate Professor, Department of Pediatrics, Karolinska University Hospital, Karolinska Institutet, Sweden

Co-Chair:

Dr. John DeVincenzo, Professor, University of Tennessee, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: HIV /AIDS in China-A Potential Epidemic?
Dr. Konglai Zhang, Professor, Department of Epidemiology, Peking Union Medical College, China

14:00-14:25

Title: Seroprevalence of Kaposi's Sarcoma-associated Herpesvirus and Risk Factors in Xinjiang, China
Dr. Linding Wang, Associate Professor, Tumor Virology Group, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS), China

14:25-14:50

Title: A Study on the Indicators to Classify Types of Measles Outbreak and Specialize Its Containment Strategies Based on the Experience of Four Measles Outbreaks and Its Containment in Guangxi
Dr. Jiatong Zhuo, Deputy Director, Guangxi CDC, China

14:50-15:15

Title: Profile of Occult Hepatitis "B" Virus Infection In Egyptian Patients
Dr. Zeinab Nabil Ahmed Said, Professor, Microbiology Department, Faculty of Medicine (for Girls)-Al-Azhar University, Egypt

15:15-15:30

Coffee Break

15:30-15:55

Title: Identification of Genotype 3 Hepatitis E Virus in Shanghai and A hypothetic Homeostasis Mechanism of Hepatitis E Virus
Dr. Zhen Li, Senior Researcher, Institute of Animal Science, Veterinary Medicine, Shanghai Academy of Agricultural Sciences, China

15:55-16:20

Title: Human Polyomavirus, Parvovirus or Herpes Virus DNA were not Detected in Guthrie Cards from Children Who Later Developed Acute Lymphoblastic Leukemia (ALL)
Dr. Britt Gustafsson, Associate Professor, Department of Pediatrics, Karolinska University Hospital, Karolinska Institutet, Sweden

16:20-16:45

Title: Why HPV Becomes Carcinogenic: The Epigenetic Role of Transcription Factor and Its Clinical Implications
Dr. Ashfaq M. Khan, Clinical Research Fellow, University College London, UK

16:45-17:10

Discussion

Track1-2: Viral Drug Resistance and Genotyping
Time: July 19, 2009, Sunday, 9:00-11:50, Room 311-A

Session Chair:

Dr. Herve J Fleury, Professor, University Hospital of Bordeaux, France

Co-Chair:

Dr. Changqing Zeng, Professor, Beijing Institute of Genomics, Chinese Academy of Sciences, China

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: Deletion and Insertion Patterns in HBV Genomes and Their Correlations to the Drug Resistance
Dr. Changqing Zeng, Professor, Beijing Institute of Genomics, Chinese Academy of Sciences, China

09:30-09:55

Title: Molecular Variability of HIV-1: Consequences for Public Health
Dr. Herve J Fleury, Professor, University Hospital of Bordeaux, France

09:55-10:20

Title: Mechanisms of Drug Resistance in Herpesviruses
Dr. Graciela Andrei, Associate Professor, Rega Institute for Medical Research, Belgium

10:20-10:35

Coffee Break

10:35-11:00

Title: Antiviral Drug Resistance in Chronic Hepatitis B-New Paradigm in The Therapy?
Dr. Viktorija Chalovska Ivanova, Professor, Clinic of Gastroenterohepatology, Medical Faculty, Republic of Macedonia

11:00-11:25

Title: Mechanisms by which N348I in the Connection Domain of HIV-1 Reverse Transcriptase (RT) Confers RT Inhibitor Resistance
Ms. Jessica Radzio, Department of Infectious Disease and Microbiology, University of Pittsburgh, USA

11:25-11:50

Discussion

Track1-3: Retroviruses
Time: July 19, 2009, Sunday, 13:30-17:30, Room 311-A

Session Chair:

Dr.Shan-Lu Liu, Assistant Professor, Canada Research Chair, Department of Microbiology and Immunology, McGill University, Canada

Co-Chair:

Dr. Xinhong Dong, Assistant Professor, Center for AIDS Research, Meharry Medical College, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Retroviral Oncogenesis: New Lessons from Sheep Retroviruses and Implications for Human Lung Cancer
Dr.Shan-Lu Liu, Assistant Professor, Canada Research Chair, Department of Microbiology and Immunology, McGill University, Canada

14:00-14:25

Title: Host-virus Interactions in the Assembly of HIV-1
Dr. Xinhong Dong, Assistant Professor, Center for AIDS Research, Meharry Medical College, USA

14:25-14:50

Title: Portuguese Cohort: Raltegravir with Optimized Background Therapy (OBT) In Multiple Experienced HIV-infected Patients
Dr. Manuela Doroana, Professor, Medical School of Lisbon, Portugal

14:50-15:15

Title: HIV-1 Latency: Significance of a Novel Cellular miRNA
Dr. Deepak Kaul, Professor & Head, Department of Experimental Medicine & Biotechnology, Postgraduate Institute of Medical Education & Research, India

15:15-15:40

Title: Study of Mechanism of Action and Inhibition of HIV-1 Integrase by Using Modified Oligonucleotides
Dr. Marina B. Gottikh, Professor, Belozersky Institute of Physical Chemical Biology, Lomonosov Moscow State University, Russia

15:40-16:05

Title: Basic and Translational Studies on the Human Retrovirus Infection by HIV-1 and HTLV-I
Dr. Naoki Yamamoto, Director, AIDS Research Center, National Institute of Infectious Diseases, Japan

16:05-16:30

Title: HIV-1-Resistant Sex Workers Overexpress Novel Antiproteases and Innate Anti-viral Factors in their Cervical Mucosa. Protective Milieu against HIV-1 Infection?
Dr. Adam Burgener, Lecturer, Public Health Agency, University of Manitoba, Canada

16:30-16:55

Title: Potential for Ginseng to Reverse Oxidative Side Effects of Anti-HIV Medicines
Dr. Lawrence S. Lee, Assistant Professor, Department of Medicine, National University of Singapore, Singapore

16:55-17:20

Title: The HAART Era & HIV-1 CNS Infection-The Challenge & Perspectives on Therapy.
Dr. Augusto César Penalva de Oliveira, Clinical Research Unit in Human Retrovirology, University of Campinas, Institute of Infectious Diseases Emílio Ribas, Brazil

17:20-17:30

Discussion

Track1-4: Respiratory, Herpes Virus, Dengue Fever and other Emerging Viruses (Part I)
Time: July 19, 2009, Sunday, 09:00-12:30, Room 311-B

Session Chair:

Dr. Wouter Schul, Senior Research Investigator, Dengue Unit, Novartis Institute for Tropical Diseases Pte Ltd, Singapore

Co-Chair:

Dr. Qianjun Li, Assistant Professor, Department of Medicine, University of Alabama at Birmingham, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: New Approaches to Anti-dengue Drug Discovery
Dr. Wouter Schul, Senior Research Investigator, Dengue Unit, Novartis Institute for Tropical Diseases Pte Ltd, Singapore

09:30-09:55

Title: Antiviral Drug Discovery against Dengue Virus
Dr. Qianjun Li, Assistant Professor, Department of Medicine, University of Alabama at Birmingham, USA

09:55-10:20

Title: SKI-1/S1P Inhibitors - An Antiviral Approach against Arenaviruses
Dr. Ute Stroeher, Head, Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Canada

10:20-10:35

Coffee Break

10:35-11:00

Title: Protein Degradation System: A Novel Therapeutic Target for Coxsackievirus Replication?
Dr. Honglin Luo, Assistant Professor, University of British Columbia-St. Paul's Hospital, Canada

11:00-11:25

Title: Structure and Function of Flavivirus NS5 Methyltransferase
Dr. Hongmin Li, Assistant Professor, School of Public Health, USA

11:25-11:50

Title: Proton Conduction and Drug Binding in the M2 Channel from Influenza A Virus Dissected by Molecular Simulation
Dr. Matteo Dal Peraro, Assistant Professor, Laboratory for Biomolecular Modeling, Institute of Bioengineering, School of Life Sciences, Swiss Federal Institute of Technology, Switzerland

11:50-12:15

Title: Effect of Low-concentration Chlorine Dioxide Gas against Respiratory Virus Infection
Dr. Norio Ogata, Chief Investigator, Research Institute, Taiko Pharmaceutical Co., Ltd. Japan

12:15-12:30

Discussion

Track1-4: Respiratory, Herpes Virus, Dengue Fever and other Emerging Viruses (Part II)
Time: July 20, 2009, Monday, 09:00-12:00, Room 311-A

Session Chair:

Dr. Felix Rey, Director, Department of Virology, Institut Pasteur, France

Co-Chair:

Dr. Hua Zhu, Associate Professor, University of Medical and Dentistry of New Jersey, New Jersey Medical School, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: X-ray Structure of a Respiratory Syncytial virus Nucleoprotein-RNA Template-like Assembly
Dr. Felix Rey, Director, Department of Virology, Institut Pasteur, France

09:30-09:55

Title: Tick-borne Encephalitis in Europe, Far East and Asia and Climate Change
Dr. Jochen Süss, Associate Professor, National Reference Laboratory for Tick-borne Diseases, Friedrich-Loeffler-Institute, Germany

09:55-10:20

Title: Functional Profiling of Varicella-Zoster Virus Genome
Dr. Hua Zhu, Associate Professor, University of Medical and Dentistry of New Jersey, New Jersey Medical School, USA

10:20-10:35

Coffee Break

10:35-11:00

Title: Efficacy of Arbidol on Lethal Hantaan Virus Infections in Vitro and in Vivo
Dr. Zhanqiu Yang, Professor, State Key Laboratory of Virology, Institute of Medical Virology, School of Medicine, Wuhan University, China

11:00-11:25

Title: Identification of Inhibitors Targeting Early Events of Herpes Virus Infection
Dr. Tao Peng, Professor, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, China

11:25-11:50

Title: Potential Roles of HLA-G Expression During HCMV Infection
Dr. Wei Hua Yan, Associate Professor, Medical Research Center, Taizhou Hospital of Zhejiang Province, China

11:50-12:00

Discussion

Track1-5: Antivirals and Intervention and Behavioral Intervention
Time: July 20, 2009, Monday, 13:30-17:30, Room 311-A

Session Chair:

Dr. Tim J Harrison, Reader, University College London Medical School, UK

Co-Chair:

Dr. Ludmila Viksna, Professor & Chief, Riga Stradins University, Latvia

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Successful Treatment of Chronic Viral Hepatitis C: Biochemical Criteria for Patient Selection
Dr. Ludmila Viksna, Professor, Chief of Infectology Chair, Riga Stradins University, Latvia

14:00-14:25

Title: Can The Risk of Primary Liver Cancer be Reduced by Antiviral Therapy of Hepatitis B Carriers?
Dr. Tim J Harrison, Reader, University College London Medical School, UK

14:25-14:50

Title: Alternative Method for Viruses Airborne Contamination Control
Ms. Elina Machefer, Asia Manager, Bertin Technologies, France

14:50-15:15

Title: Early Warning Indicators of HIV Drug Resistance. How they Guide to Improve Adherence to the Treatment in Resources-limited Settings
Dr. Nando Campanella, HIV Country Officer, WHO Angola, Angola

15:15-15:30

Coffee Break

15:30-15:55

Title: HIV Prevalence Among Survivors of Sexual Assault in a Region of South Africa: Another Potential Means of Estimating HIV Prevalence in the General Population?
Dr. Enoch N Kwizera, Professor and HOD, Faculty of Health Sciences, Walter Sisulu University, South Africa

15:55-16:20

Title: Treating Children with Acute Severe HIV-related Lung Disease in South Africa-A Strategy that has Improved Survival
Dr. Robin Green, Professor, Department of Pediatrics, University of Pretoria, South Africa

16:20-16:45

Title: Perinatal HIV Infection and The Strategy for Prevention of HIV MTCT in Japan–Based on The National Cooperative Group Study Supported by Ministry of Health, Labor and Welfare, 2003-2008
Dr. Noriyuki Inaba, Vice President, Dokkyo Medical University, Japan

16:45-17:10

Title: Overview of Mathematical Models Evaluating Pandemic Influenza Mitigation Strategies
Ms. Beate Sander, Department of Health Policy, Management and Evaluation, University of Toronto, Canada

17:10-17:30

Discussion

Track2-1: Upstream Platform Technologies for Antiviral Drug Discovery
Time: July 18, 2009, Saturday, 13:30-17:30, Room 311-B

Session Chair:

Dr. Yu-Mei Wen, Professor, Institute of Medical Microbiology, Fudan University, China

Co-Chair:

Dr. Zhenhong Yuan, Professor, Institute of Biomedical Sciences, Shanghai Public Health Center, Fudan University, China

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: Sculpting the Immunological Response to Dengue Fever by Polytopic Vaccination
Dr. Michael W. Deem, Professor, Department of Bioengineering, Rice University, USA

14:00-14:25

Title: Applying Bioinformatics to Hurdle the Discovery of Broad-Spectrum Antivirals
Dr. Yongliang Yang, Associate Professor, Visiting Fellow, Dalian University of Technology/ Harvard University, China

14:25-14:50

Title: Species-Typical Behaviours of the Mouse: a Sensitive, Mouse-friendly Way to Assess Viral and Antiviral Agents Affecting Behavior
Dr. Robert Deacon, Professor, Department of Experimental Psychology, University of Oxford, UK

14:50-15:15

Title: An Innovative Strategy to Discover and Develop New Anti-infective Agents for Herpes Desease
Dr. Gerald Kleymann, CEO, Primedica GmbH, Germany

15:15-15:30

Coffee Break

15:30-15:55

Title: The Three-dimensional Structure of the Arp2/3 Complex Mediated Actin Branch Junction and Its Implication for Viral Intra-host Motility
Dr. Niels Volkmann, Associate Professor, Burnham Institute for Medical Research, USA

15:55-16:20

Title: Drug Discovery against Influenza Virus
Dr. John T. An Hsu, Investigator, Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Taiwan

16:20-16:45

Title: Novel Antiviral Strategies against Hepatitis C Virus
Dr. Saumitra Das, Professor, Department of Microbiology and Cell Biology, Indian Institute of Science, India

16:45-17:10

Title: New Insights into the Interactions between Interferon and Hepatitis B Virus: Implications in Identifying New Tools for Combating Infectious Diseases
Dr. Zhenhong Yuan, Professor, Institute of Biomedical Sciences, Shanghai Public Health Center, Fudan University, China

17:10-17: 30

Discussion

Track2-2: Medicinal Chemistry and Rational Drug Design of Antivirals
Time: July 19, 2009, Sunday, 9:00-12:00, Room 311-C

Session Chair:

Dr. Romu Corbau, Associate Research Fellow, Pfizer Global Research and Development, UK

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Keynote Speech:
Title: The Discovery of UK-453,061
Dr. Romu Corbau, Associate Research Fellow, Pfizer Global Research and Development, UK

09:30-09:55

Title: A Computer-based Strategy for Designing Molecules with Improved Potency and ADMET Properties
Dr. David Miller, Team Leader, Discovery Cheminformatics, Simulations Plus, USA

09:55-10:20

Title: Acyclic Nucleoside Phosphonates
Dr. Petr Jansa, Academy of the Czech Republic, Czech

10:20-10:35

Coffee Break

10:35-11:00

Title: How to Utilize Capillary Zone Electro Pherogram to Realize Hepato-therapeutic Natural Alkaloids
Dr. Pauli Virtanen, Professor, PV-Ceuticals Oy, Finland

11:00-11:25

Title: Computer-aided Design of Ligands Targeting HIV Biomolecules in Their Cellular Environment
Dr. Paolo Carloni, Full Professor, International School for Advanced Studies (SISSA), Italy

11:25-11:50

Title: Synthesis and Evaluation of Novel Tea Catechin Derivative as Anti-influenza Viral Agents
Dr. Kunihiro Kaihatsu, Assistant Professor, Departments of Organic Fine Chemicals, Osaka University, Japan

11:50-12:00

Discussion

Track2-3: Novel Drug Delivery System for Antivirals
Time: July 19, 2009, Sunday, 13:30-17:10, Room 311-B

Session Chair:

Dr. A. Omri, Professor, Director, Laurentian University, Canada

Co-Chair:

Dr. Anant Paradkar, Professor, Pharmaceutical Engineering Science, University of Bradford, UK

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Challenges and Delivery Systems for Curcumin
Dr. Anant Paradkar, Professor, Pharmaceutical Engineering Science, University of Bradford, UK

14:00-14:25

Title: Self-assembled Drug Delivery Systems for Antiviral Therapy
Dr. Yiguang Jin, Associate Professor, Department of Pharmaceutical Chemistry, Beijing Institute of Radiation Medicine, China

14:25-14:50

Title: Hepatic Delivery of siRNA against Hepatitis C Virus Using Apolipoprotein A-I as a Targeting Ligand
Dr. Meehyein Kim, Principal Research Scientist, Mogam Biotechnology Research Institute (MBRI), Korea

14:50-15:15

Title: Enhancing the Treatment of Infectious Diseases through Nanomedicine
Dr. Hulda Shaidi Swai, Principal Researcher, Polymers and Bioceramics, CSIR-Materials Science and Manufacturing, Council for Scientific and Industrial Research, South Africa

15:15-15:30

Coffee Break

15:30-15:55

Title: Lipid-Based Drug Delivery Systems for Treatment of Pulmonary Infection in Cystic Fibrosis Patients
Dr. A. Omri, Professor, Director, Laurentian University, Canada

15:55-16:20

Title: Newer Approach in Product Development for Antiretroviral Drug Therapy
Dr. Jyosna Torne, Senior Research Scientist, Piramal Pharmaceutical Development Services, India

16:20-16:45

Title: Liposomal Drug Delivery System for HSV-tk Suicide Gene Therapy
Dr. Yoshie Maitani , Professor, Institute of Medicinal Chemistry, Fine Drug Targeting Research Laboratory, Hoshi University, Japan

16:45-17:10

Discussion

Track2-4: RNAi, microRNA and Antisense as Antivirals
Time: July 20, 2009, Monday, 9:00-11:50, Room 311-B

Session Chair:

Dr. Bo Rode Hansen, Director, Santaris Pharma, A/S., Denmark

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: RNA Interference for the Treatment of Viral Cancers
Dr. Nigel AJ McMillan, Deputy Director, UQ Diamantina Institute, Australia

09:30-09:55

Title: Therapeutic Silencing of MicroRNA -122 in Primates with Chronic HCV Infection
Dr. Bo Rode Hansen, Director, Santaris Pharma, A/S., Denmark

09:55-10:20

Title: Liver Specific microRNA miR -122 in Hepatitis C Virus Infection and Related Liver Diseases
Dr. Jinhong Chang, Assistant Professor, Drexel University College of Medicine, USA

10:20-10:35

Coffee Break

10:35-11:00

Title: Results of a Multi-Center Randomized, Double-Blind, Placebo-Controlled Study of an RNAi Therapeutic, ALN-RSV01, in Lung Transplant Patients Infected with Respiratory Syncytial Virus (RSV)
Dr. Allan R Glanville, Director & Professor, University of Tennessee School of Medicine, USA

11:00-11:25

Title: Knockdown of RNA Dependent RNA Polymerase by RNA Interference for Blocking of Betanodavirus Replication and Necrotic Cell Death
Dr. Jiann Ruey Hong, Associate Professor, Laboratory of Molecular Virology and Biotechnology, Institute of Biotechnology, National Cheng Kung University, Taiwan

11:25-11:50

Discussion

Track2-5: DNA and RNA Polymerase Inhibitors
Time: July 20, 2009, Monday, 13:30-15:30, Room 311-B

Session Chair:

Dr. Klaus Klumpp, Director, Roche Palo Alto LLC, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: The Design, Synthesis and Antiviral Potency of 4' -Substituted Nucleosides
Dr. Mark Smith, Research Scientist, Roche Palo Alto, USA

14:00-14:25

Title: Structural Studies of Hepatitis C Virus NS5B Polymerase Bound to Non-nucleoside Inhibitors (NNIs)
Dr. Andrea Carfi, Group Leader, Protein Crystallography Unit, IRBM P. Angeletti and Merck Research Laboratories, Italy

14:25-14:50

Title: New Inhibitors of HIV and HCV Replication
Dr. Sergey Kochetkov, Professor, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Russia

14:50-15:15

Title: 2'-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication
Dr. Klaus Klumpp, Director ,Roche Palo Alto LLC ,USA

15:15-15:30

Coffee Break

Track2-6: Attachment, Entry and Fusion Inhibitors as Antivirals
Time: July 18, 2009, Saturday, 13:30-16:45, Room 311-C

Session Chair:

Dr. Andrea Wolkerstorfer, Head, Molecular Biology, Onepharm Research & Development GmbH, Austria

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Hepatitis C Virus Entry for Development of Novel Antivirals and Vaccines
Dr. Mirjam B. Zeisel, Senior Research Associate, Inserm U748, Institute of Virology, University of Strasbourg, France

14:00-14:25

Title: Glycyrrhizin Inhibits Influenza A Virus Uptake into the Cell
Dr. Andrea Wolkerstorfer, Head, Molecular Biology, Onepharm Research & Development GmbH, Austria

14:25-14:50

Title: Discovery of Potent Non-nucleoside Inhibitors of Measles Virus
Dr. Aiming Sun, Associate Director, Emory Drug Discovery Institute, Emory University, USA

14:50-15:15

Title: Inhibition of HIV-1 Entry by a Binding Domain of Porphyromonas Gingivalis Gingipain
Dr. Hua Xie, Professor, Department of Oral Biology, Meharry Medical College, USA

15:15-15:30

Coffee Break

15:30-15:55

Title: Fusion Core Structure of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV): In Search of Potent SARS-CoV Entry Inhibitors
Dr. Ngai Sai Ming, Associate Professor, the Chinese University of Hong Kong, China

15:55-16:20

Title: Receptor and Low pH Coactivate Membrane Fusion by Oncogenic Retrovirus Envelopes
Dr. Shan-Lu Liu, Canada Research Chair & Assistant Professor, Department of Microbiology and Immunology, McGill University, Canada

16:20-16:45

Discussion

Track2-7: Interferons
Time: July 19, 2009, Sunday, 13:30-15:30, Room 311-C

Session Chair:

Dr. Nigel Stevenson, Research Scientist, Trinity College Dublin, Ireland

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: An Antiviral Drug Process Improvement: Mass Spectrometric Characterization of the Isoforms in E.Coli Recombinant DNA-derived Interferon Alpha-2b
Dr. Birendra N. Pramanik, Distinguished Fellow, Schering-Plough Research Institute, USA

14:00-14:25

Title: Modulation of Cellular Stress Signaling and Interferon Response by SARS Coronavirus Structural Proteins
Dr. Dongyan Jin, Associate Professor, Department of Biochemistry, University of Hong Kong, Hong Kong, China

14:25-14:50

Title: HIV Evasion of the Immune System: Dysregulation of Antiviral Systems and Perturbation of Cell Signaling Pathways
Dr. Allan Lau, Professor, Cytokine Biology Group, Departments of Paediatrics, the University of Hong Kong, China

14:50-15:15

Title: The ISG15 and Ubiquitin Pathways: Potential Targets for Antiviral Therapy
Dr. Shyamal D. Desai, Assistant Professor, Department of Biochemistry and Molecular Biology, LSU Health Science Center, USA

15:15-15:30

Coffee Break

Track2-8: Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Time: July 19, 2009, Sunday, 15:30-17:30, Room 311-C

Session Chair:

Dr. Klaus Klumpp, Director, Roche Palo Alto LLC , USA

15:30-15:35

Welcome: Session Introduction

15:35-16:00

Title: Discovery of New HIV Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) with Higher Barrier to Resistance Potential
Dr. Klaus Klumpp, Director, Roche Palo Alto LLC, USA

16:00-16:25

Title: Mechanisms of Inhibition of HIV Replication by Non-nucleoside Reverse Transcriptase Inhibitors
Dr. Nicolas Sluis Cremer , Professor & Director, Division of Infectious Diseases, University of Pittsburgh School of Medicine, USA

16:25-16:50

Title: Visualizing the Dynamic Interactions of HIV Reverse Transcriptase with Nucleic Acid at the Single-molecule Level
Mr. Shixin Liu, Ph.D. Candidate, Department of Chemistry and Chemical Biology, Harvard University, USA

16:50-17:15

Title: Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in HIV-1 Infected Patients from Argentine
Dr. Pablo Parenti, Instituto CAICI, Rosario, Argentina

17:15-17:30

Discussion

Track2-9: Antivirals in the Postgenomics Era: Research and Technology Development
Time: July 20, 2009, Monday, 9:00-12:30, Room 311-C

Session Chair:

Dr. Denong Wang , Director, Stanford Tumor Glycome Laboratory. Stanford University, USA

Co-Chair:

Dr. Srinubabu Gedela, Director, OMICS Publishing Group, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:55

Title: Immunogenic Sugar Moieties of HIV-1 and SARS-CoV and Their Therapeutic Potential
Dr. Denong Wang, Director, Stanford Tumor Glycome Laboratory. Stanford University, USA

09:55-10:20

Title: Computational Systems Biology of Glycome: Mining and Validation
Dr. Srinubabu Gedela, Director, OMICS Publishing Group, USA

10:20-10:35

Coffee Break

10:35-11:00

Title: Novel Carbohydrate Cluster Microarrays Technology for Profiling Glycan Functions
Dr. Xichun Zhou, Biotechnology Program Manager, Senior Research Scientist, ADA Technologies Inc, USA

11:00-11:25

Title: Cytoplex Bead-based Technology for Clinical Diagnosis.
Dr. Jay Yuan, Product Development Scientist, Thermo Fisher Scientific Inc, USA

11:25-11:50

Title: Novel Fucosylated Markers to Monitor the Progression and Recovery of Virally Induced Liver Disease
Dr. Anand Mehta, Associate Professor & Associate Director, Drexel Institute for Biotechnology and Virology Research, Drexel University College of Medicine, USA

11:50-12:20

Title: Designing Short Peptides as Viral Vaccines
Dr. P. Kangueane, Professor, AIMST University, Malaysia

12:20-12:30

Discussion

Track2-10: Protease and Integrase Inhibitors
Time: July 20, 2009, Monday, 15:30-17:30, Room 311-B

Session Chair:

Dr. Michael G. Murray, Director, Southern Research Institute, USA

Co-Chair:

Dr. Viktor Lozitsky, Deputy Director, I.I.Mechnikov Ukrainian Research Anti-Plague Institute, Laboratory of Chemotherapeutical & Immune-Biological Agents, Ukraine

15:30-15:35

Welcome: Session Introduction

15:35-16:00

Title: From Bedside to Bench-Clinical Demands on HIV Drug Development
Dr. Nils Holger von Hentig, Postdoctoral Lecturer, Johann Wolfgang Goethe-University, Germany

16:00-16:25

Title: The Role of Proteolytic Systems in Infectious Process Development during Some Viral Diseases. Anti-Flu and Anti-HSV Efficacy of Proteolytic Inhibitors (Experimental & Clinical Data)
Dr. Viktor Lozitsky, Deputy Director on Scientific Work, I.I.Mechnikov Ukrainian Research Anti-Plague Institute, Laboratory of Chemotherapeutical & Immune-Biological Agents, Odessa, Ukraine

16:25-16:50

Title: Proteomic Analysis and Protease Inhibitor Therapy for Severe Influenza Pneumonia in Mice
Dr. Masafumi Seki, Assistant Professor, Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Global COE Program, Nagasaki University, Japan

16:50-17:15

Title: Therapeutic Drug Monitoring of Protease and Integrase Inhibitors
Dr. Masaaki Takahashi, Senior Pharmacist, Department of Pharmacy and Clinical Research Center, National Hospital Organization Nagoya Medical Center, Japan

17:15-17:30

Discussion

Track2-11: Neuraminidase Inhibitors ( NIs ) (I)
Time: July 18, 2009, Saturday, 13:30-17:30, Room 310

Session Chair:

Dr. David Reddy, Leader, Global Influenza Pandemic Task Force Leader, F. Hoffmann-La Roche in Basel, Switzerland

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Clinical Effectiveness of Oseltamivir and Zanamivir from the 2003-2004 to the 2008-2009 Influenza Seasons in Japan
Dr. Hideyuki Ikematsu, Director, Department of Clinical Research. Haradoi Hospital in Fukuoka, Japan

14:00-14:25

Title: Increasing the Availability of the Antiviral Tamiflu (Oseltamivir) for the Management of Influenza A H5N1 Infection and for Pandemic Preparedness Planning
Dr. David Reddy, Leader, Global Influenza Pandemic Task Force Leader, F. Hoffmann-La Roche in Basel, Switzerland

14:25-14:50

Title: Source of Oseltamivir Resistance in Avian Influenza A/H5N1 Neuraminidases
Dr. Supot Hannongbua, Professor, Department of Chemistry, Faculty of Science, Chulalongkorn University, Thailand

14:50-15:15

Title: Interaction of Influenza Virus NIs with Human Neuraminidases
Dr. Leonard M.G. Chavas, Assistant Professor, Structural Biology Research Center, High Energy Accelerator Research Organization (KEK), Japan

15:15-15:30

Coffee Break

15:30-15:55

Title: CS-8958, A Long Acting Neuraminidase Inhibitor (LANI) for Influenza
Dr. Makoto Yamashita, Director, Biological Res. Labs. IV, Daiichi Sankyo Co., Ltd., Japan

15:55-16:20

Title: Structure-based Design of Flexible Inhibitor Library Targeting Influenza Virus Neuraminidase
Dr. Junmin Quan, Associate Professor, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, China

16:20-16:45

Title: 10 Years Influenza Therapy with Antivirals (Zanamivir and Oseltamivir) 262 Patients All As Outpatients
Dr. Georg E. Vogel, Professor, Department of Internal Medicine-Internal Practice, Technical University of Munich, Germany

16:45-17:10

Title: Micronutrients as Inhibitors of Influenza a Virus (H1N1)-Associated Neuraminidase Activity, Viral Infectivity and Metalloproteinase Induced in Host Cells
Dr. Raxit J. Jariwalla, Senior Researcher, Dr. Rath Research Institute, USA

17:10-17:30

Discussion

Track2-11: Neuraminidase Inhibitors (Nis) (II)
Time: July 20, 2009, Monday, 13:30-16:45, Room 311-C

Session Chair:

Dr. Wilfred Li, Executive Director, National Biomedical Computation Resources, San Diego Supercomputer Center, University of California, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Evaluation of the Efficacy and Safety of a Statin/Caffeine Combination against H5N1, H3N2 and H1N1 Virus Infection in BALB/c Mice
Dr. Jiahai Lu, Professor, School of Public Health, Sun Yat-sen University, China

14:00-14:25

Title: Avian Influenza A/H5N1 Neuraminidase Expressed in Yeast with A Functional Head Domain
Dr. Suganya Yongkiettrakul, Research Scientist, Protein-Ligand Engineering and Molecular Biology Laboratory, BIOTEC Central Research Unit, National Science and Technology Development Agency, Thailand

14:25-14:50

Title: Structural Basis of Oseltamivir Resistance of Mutant Infulenza N1 Neuraminidase
Dr. Junfeng Liu, Division of Virology and Molecular Structure, MRC- National Institute for Medical Research, UK

14:50-15:15

Title: Integrative High Throughput Screening, Bioassay Guided Isolation, Virtual Screening and Drug Design Approaches for Discovery of Candidates as Infulenza Neuraminidase Inhibitors
Dr. Ailin Liu, Professor National Center for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences, China

15:15-15:30

Coffee Break

15:30-15:55

Title: Search for Novel Neuraminidase Inhibitors: Evidence of Membrane Stabilization by Oseltamivir Derivatives Using Molecular Docking, NMR and DSC Methods
Dr. Sudha Srivastava , Professor, National Facility for High Field NMR, Tata Institute of Fundamental Research, India

15:55-16:20

Title: Wild Type and Mutant Neuraminidase Inhibitors from Ensemble Based Virtual Screening
Dr. Wilfred Li, Executive Director, National Biomedical Computation Resources, San Diego Supercomputer Center, University of California, USA

16:20-16:45

Title: An In Vitro Study of the Elimination of Oseltamivir Carboxylate by Haemofiltration
Dr. Gordon Y.S. Choi, Honorary Assistant Professor, Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, China

Track3-1: Antiviral Gene and Cell Therapy
Time: July 19, 2009, Sunday, 9:00-12:00, Room 302

Session Chair:

Dr. Frederic Paques, CSO, Cellectis SA, France

Co-Chair:

Dr. Geoff Symonds, CSO, Calimmune Inc, St Vincent's Centre for Applied Medical Research, Australia

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: Meganucleases: A Novel Anti-viral Strategy
Dr. Frederic Paques, CSO, Cellectis SA, France

09:30-09:55

Title: The first proof-of-concept for a therapeutic effect of RNA interference in man: development of an antiviral against Respiratory Syncytial Virus (RSV)
Dr. John P. DeVincenzo, Professor, University of Tennessee, USA

09:55-10:20

Title: Effects of Herpes Simplex Virus Thymidine Kinase Gene Transduction on Tumor Cell Biology
Dr. Riad Agbaria, Senior Lecturer, Department of Clinical Pharmacology, Ben-Gurion University of the Negev, Israel

10:20-10:35

Coffee Break

10:35-11:00

T Title: Cell delivered gene therapy for HIV
Dr. Geoff Symonds, CSO, Calimmune Inc, St Vincent's Centre for Applied Medical Research, Australia

11:00-11:25

Title: Demonstration of a Novel HIV-1 Restriction Phenotype from a Human T Cell Line
Dr. Yanxing Han, Assistant Professor, Chinese Academy of Medical Sciences, China

11:25-11:50

Title: HIV-1 Gene Therapy Strategies
Dr. Sadhna Joshi, Associate Professor, Department of Molecular Genetics, Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada

11:50-12:00

Discussion

Track3-2: Antibodies for Antiviral Therapeutics
Time: July 19, 2009, Sunday, 13:30-15:30, Room 303

Session Chair:

Dr. Soren Bregenholt, COO, Project & Portfolio Management, Symphogen A/S, Denmark

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Recombinant Human Polyclonal Antibodies–New Treatment Modalities in Viral Infections
Dr. Soren Bregenholt, COO, Project & Portfolio Management, Symphogen A/S, Denmark

14:00-14:25

Title: Monoclonal Antibodies to Respiratory Syncytial Virus (RSV) G-protein: Therapeutic Implications of combined Viral Neutralization plus Immune Modulation
Dr. John P. DeVincenzo, Professor, University of Tennessee, Methodist/LeBonheur Hospitals, USA

14:25-14:50

Title: Mechanistic Correlates of Antibody-Mediated Protection against Flavivirus Infection
Dr. Daved H Fremont, Associate Professor, Washington University School of Medicine, USA

14:50-15:15

Title: Development of a Therapeutic Monoclonal Antibody against Hepatitis B Virus
Dr. Se Ho Kim, Research Director, Research Center, Antibody Engineering Lab., Green Cross Corp., Korea

15:15-15:30

Coffee Break

Track3-3 ( I ) : HIV Vaccines
Time: July 20, 2009, Monday, 9:00-12:30, Room 310

Session Chair:

Dr. Eric Sandstr?m, Professor, Karolinska Institutet, Sweden

Co-Chair:

Dr. Yiming Shao, Chief Expert, National Center for AIDS/STD Control and Prevention, China Center for Disease Control and Prevention, China

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: AIDS Vaccine Research, from Laboratory Design to Clinical Study
Dr. Yiming Shao, Chief Expert, National Center for AIDS/STD Control and Prevention, China Center for Disease Control and Prevention, China

09:30-09:55

Title: Results from the EUROVAC Clinical Trials: DNA/NYVAC Induces Strong, Broad and Stable Immune Response
Dr. Hans Wolf, Professor, Institute for Medical Microbiology and Hygiene, University of Regensburg, Germany

09:55-10:20

Title: HIV DNA Vaccine-Optimized Design and Delivery
Dr. Yong Liu, Professor, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, china

10:20-10:35

Coffee Break

10:35-11:00

Title: Characterization of a Replication-competent Modified Vaccinia Tian Tan (MVTT) as a Vaccine Vector
Dr. Zhiwei Chen, Director, AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, China

11:00-11:25

Title: DNA Prime and Pox Virus Boost as a Potential HIV Vaccine for China
Dr. Eric Sandstr?m, Professor, Karolinska Institutet, Sweden

11:25-11:50

Title: Induction of Cross-reactive Immune Responses by Centralized HIV-1 Envelope Genes
Dr. Feng Gao, Professor & Director, Laboratory of Molecular Virology, Human Vaccine Institute, Duke University Medical Center, USA

11:50-12:15

Title: Intradermal Electroporation as a Means to Enhance Immune Responses to Genetic Vaccines
Dr. Andreas Brave, Karolinska Institutet, Swedish Institute for Infectious Disease Control, Sweden

12:15-12:30

Discussion

Track3-3 ( I I ) : Novel Antiviral Vaccines
Time: July 19, 2009, Sunday, 15:30-16:35, Room 303

Session Chair:

Dr. Alexander von Gabain, Co-Founder and CSO, Intercell AG, Austria

Co-Chair:

Dr. Jingdong Tian, Assistant Professor, Departments of Biomedical Engineering & Institute for Genome Sciences and Policy, Duke University, USA

15:30-15:55

Title: An Inactivated Cell Culture Derived JEV Vaccine (IC51) towards Worldwide Licensure
Dr. Alexander von Gabain , Co-Founder and CSO, Intercell AG, Austria

15:55-16:20

Title: Combinatorial Synthetic DNA Vaccines for Combating Emerging Influenza Pandemic
Dr. Jingdong Tian, Assistant Professor, Departments of Biomedical Engineering & Institute for Genome Sciences and Policy, Duke University, USA

16:20-16:35

Discussion

Track4-1: Antivirals on HIV
Time: July 18, 2009, Saturday, 13:30-17:10, Room 302

Session Chair:

Dr. Jose M. Zuniga, President & CEO, International Association of Physicians in AIDS Care (IAPAC), USA

Co-Chair:

Dr. Changhua Ji, Project leader, Viral Diseases Area, Roche Palo Alto, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: Combining Antivirals with Prevention Interventions to Reduce High Risk Behavior and Community-Wide Rates of Infection: An Evidence-Based Model for Training Peer Educators
Dr. Barbara C. Wallace, Professor & Director, Global HELP-Health Education Leadership Program, Department of Health and Behavior Studies, Columbia University, USA

14:00-14:25

Title: The History and the Contribution of Antiretroviral Therapy to the Medical Field
Dr. Jose M. Zuniga, President & CEO, International Association of Physicians in AIDS Care (IAPAC), USA

14:25-14:50

Title: Discovery of Novel Antibody-based Bifunctional HIV Entry Inhibitors
Dr. Changhua Ji, Project leader, Viral Diseases Area, Roche Palo Alto, USA

14:50-15:15

Title: Selective Inhibitory Effects of Hybrid Liposomes on the Grwoth of HIV-associated Cells in Vitro and in Vivo
Dr. Ryuichi Ueoka, Professor, Graduate Course of Applied Life Science, Sojo University, Japan

15:15-15:40

Title: Characterizing a Novel Small Molecule from Non-pathogenic Oral Bacteria for HIV Drug Design
Dr. Bindong Liu, Assistant Professor, Meharry Medical College, Center for AIDS Health Disparities Research, USA

15:40-16:05

Title: A Novel Anti-HIV Strategy: Blocking Vif-Mediated APOBEC 3G Degradation
Dr. Shan Cen, Professor, Immunology Laboratory, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, China

16:05-16:30

Title: Korean Red Ginseng Attenuates HIV-1 Genes in Patients as well as Slow Progression over 20 years
Dr. Young Keol Cho, Professor, Department of Microbiology, University of Ulsan College of Medicine, South Korea

16:30-16:55

Ttile: The Anti-HIV Lectin Actinohivin-Action Mechanism and Developmental Research
Dr. Haruo Tanaka, Professor & President, Faculty of Pharmacy, Iwaki Meisei University, KIIM Pharm. Lab. Inc., Japan

16:55-17:10

Discussion

Track4-2: Antivirals on HCV and HBV (I)
Time: July 19, 2009, Sunday, 9:00-12:15, Room 310

Session Chair:

Dr. George Hill, Senior Director, Clinical Science Leader, Clinical Team Leader, Roche Palo Alto, USA

Co-Chair:

Dr. Kai Lin, Virology Group Leader, Novartis Institutes for BioMedical Research Inc., USA

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Keynote Speech:
Title: Clinical Development of Nucleoside Analogs R1626 and R7128 for the Treatment of HCV
Dr. George Hill, Senior Director, Clinical Science Leader, Clinical Team Leader, Roche Palo Alto, USA

09:30-09:55

Title: Direct Antiviral Agent Combination-The Future of HCV Treatment
Dr. Malte Schutz, Senior Director, Disease Area Management Virology, Roche Palo Alto, USA

09:55-10:20

Title: Novel Inhibitors of Hepatitis B Virus Surface Antigen
Dr. Xiaodong Xu, Executive Vice President, Enantigen Therapeutics, Inc., Pennsylvania Biotechnology Center, USA

10:20-10:35

Coffee Break

10:35-11:00

Title: Taribavirin: Discovery and Development of 2 nd Generation Ribavirin for Treatment of HCV
Dr. Jim Z. Wu, Head, Discovery Biology, Roche R&D Center, China

11:00-11:25

Title: MK-7009: A Potent Hepatitis C Virus NS3/ 4A Protease Inhibitor
Dr. Nigel J. Liverton, Senior Investigator, Merck Research Laboratories, USA

11:25-11:50

Title: Developing Novel HCV TherapiesTargeting both Viral and Host Factors
Dr. Kai Lin, Virology Group Leader, Novartis Institutes for BioMedical Research Inc., USA

11:50-12:15

Title: Thiazolides: A New Class of Antivirals Targeting Viral Glycoprotein Synthesis: Results of Preclinical and Phase II Clinical Studies in Patients with Chronic Hepatitis C
Dr. Jean-Francois Rossignol, The Romark Institute for Medical Research, Romark Laboratories, USA

Track4-2: Antivirals on HCV and HBV (II)
Time: July 19, 2009, Sunday, 13:30-17:30, Room 310

Session Chair:

Dr. Guangxiang (George) Luo, Professor, Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, USA

Co-Chair:

Dr. Zhuhui Huang, Senior Project Leader, Hepatitis Research Program, Southern Research Institute, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: Targeting the Host Protease DPP4 as a Novel Strategy for the Management of Patients with Chronic HCV
Dr. Matthew L. Albert, Head & Director, the Laboratory of Dendritic Cell Biology, Department of Immunology, Institute Pasteur, France

14:00-14:25

Title: Advances in Hepatitis C Virus Research and Antiviral Drug Discovery and Development
Dr. Guangxiang (George) Luo, Professor, Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, USA

14:25-14:50

Title: Association of Hepatitis C Virus Infection with Lipoprotein Metabolism
Dr. Jin Ye, Assistant Professor, Department of Molecular Genetics, University of Texas Southwestern Medical Center, USA

14:50-15:15

Title: Novel Ribavirin Analogues as Promising Candidates against HCV Infection
Dr. Ling Peng, Research Director, Interdisciplinary Center on Nanoscience in Marseille, National Scientific Research Center, France

15:15-15:40

Ttile: Interferon-based Therapy for Dialysis Patients with Chronic Hepatitis C: Progress and Challenges
Dr. Hung Bin Tsai, Nephrology Division, Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, Taiwan

15:40-16:05

Title: SCY-635 as Novel Therapeutic Agent for Chronic HCV Infection
Dr. Zhuhui Huang, Senior Project Leader, Hepatitis Research Program, Southern Research Institute, USA

16:05-16:30

Title: Industry-Academia Partnerships: Academic Drug Discovery
Dr. Pieter Leyssen, Industrial Research Fellow, Laboratory for Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, Belgium

16:30-16:55

Title: Discovery, Characterization and Development of Imidazopyridines Analogues: From Bovine Viral Diarrhea to Hepatitis C
Mr. Jan Paeshuyse, Rega Institute for Medical Research, Departments of Microbiology and Immunology, Belgium

16:55-17:20

Title: Autoantibodies in HCV-related Chronic Liver Disease
Dr. Takashi Himoto, Associate Professor, Department of Integrated Medicine, Kagawa University School of Medicine, Japan

17:20-17:30

Discussion

Track4-2: Antivirals on HCV and HBV (III)
Time: July 20, 2009, Sunday, 13:30-17:45, Room 310

Session Chair:

Dr. Jianming Hu, Professor, Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, USA

Co-Chair:

Dr. Sandeep Mukherjee, Associate Professor, University of Nebraska Medical Center, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Anti-flaviviral Activities of a Novel HCV p7 Inhibitor, BIT225
Dr. Michael G. Murray, Director, Southern Research Institute, USA

14:00-14:25

Title: Stereoselective Synthesis and Biological Evaluation of Azaribonucleosides and 3'Amino-2(5H) Furanones as New Inhibitors of HCV RNA Replication
Dr. Daniela Iannazzo, University of Messina, Italy

14:25-14:50

Title: Novel Therapeutic Strategy for Chronic Hepatitis C-double Filtration Plasmapheresis and ( PEG) Interferon/Ribavirin Combination Therapy
Dr. Tatsuya Ide, Assistant Professor, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan

14:50-15:15

Title: Autoimmunity: The Hepatitis C/Alpha-interferon Overlap
Dr. Vincent Ho, Clinical Senior Lecturer, School of Medicine, James Cook University, Australia

15:15-15:40

Title: Hepatitis C Virus (HCV) Regulates Signal Transducer and Activator of Transcription (STAT) Protein Expression to Escape Interferon-alpha (IFN-α) Responses
Dr. Nigel Stevenson, Research Lecturer, Trinity College Dublin, Ireland

15:40-16:05

Title: Virus-cell Interactions in Hepatitis B Virus Replication: Opportunities for Intervention
Dr. Jianming Hu, Professor, Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, USA

16:05-16:30

Title: Liposome-mediated Down Regulation of Cholesterol Biosynthesis–A Novel Antiviral Strategy
Dr. Stephanie Pollock, Research Associate, Oxford Antiviral Drug Discovery Unit, Department of Biochemistry, University of Oxford, UK

16:30-16:55

Title: Targets for Morphogenesis Inhibitors: Glycoprotein Folding, Cholesterol Synthesis, and HCV p7
Dr. Nicole Zitzmann, Department of Biochemistry, University of Oxford, UK

16:55-17:20

Title: Treatment of Hepatitits C Liver Transplantation
Dr. Sandeep Mukherjee, Associate Professor, University of Nebraska Medical Center, USA

17:20-17:45

Title: Individual vs. Network Interventions with Injection Drug Users in Ukraine
Dr. Robert E. Booth, Professor, University of Colorado Denver, USA

Track4-3: Herpes Viruses/HPV and other Major Emerging Viruses
Time: July 19, 2009, Sunday, 13:30-17:10, Room 302

Session Chair:

Dr. Xiaojiang Chen, Professor, Molecular and Computational Biology, University of Southern California, USA

Co-Chair:

Dr. Shoujiang Gao, Professor & Program Leader, University of Texas Health Science Center at San Antonio, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Prospect of New Generation of Anti-HPV Vaccines
Dr. Xiaojiang Chen, Professor, Molecular and Computational Biology, University of Southern California, USA

14:00-14:25

Title: Blocking Viral Evasion of Host Immunity: A Strategy to Increase HSV-2 Vaccine Efficacy
Dr. Sita Awasthi, Research Assistant Professor, University of Pennsylvania, USA

14:25-14:50

Title: Novel Antiviral Drug Discovery Anti-herpes Simplex Virus Type 1 Activity of Yatein in Vitro
Dr. Yuh Chi Kuo, Professor, Laboratory of Molecular Pharmacology, Institute of Life Science, Fu-Jen University, Taiwan

14:50-15:15

Title: A Novel Drug Target for Epstein-barr Virus-associated Tumors
Dr. Luwen Zhang, Associate Professor, NE Center for Virology, University of Nebraska, USA

15:15-15:30

Coffee Break

15:30-15:55

Title: Kaposi's Sarcoma-associated Herpesvirus: From Bench to Bedside
Dr. Shoujiang Gao, Professor & Program Leader, University of Texas Health Science Center at San Antonio, USA

15:55-16:20

Title: Antiviral Properties of Amiodarone: More than a Pleyotropic Effect
Dr. Aldo Baritussio, Professor, Deparment of Medical and Surgical Sciences, University of Padova, Italy

16:20-16:45

Title: Host Cellular Proteins as Potential Drug Targets for theTreatment of KSHV-associated Human Diseases
Dr. Yan Yuan, Associate Professor, University of Pennsylvania, USA

16:45-17:10

Discussion

Track4-4: Influenza/Avian Flu and Respiratory Antivirals
Time: July 20, 2009, Monday, 9:00-11:50, Room 302

Session Chair:

Dr. Keyang Wang, Scientist, Protein Sciences Corporation, USA

Co-Chair:

Dr. Langzhou Song, Senior Research Scientist, Department of Molecular Biology and Protein Science, Group Leader, VaxInnate Corporation, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: The Recombinant Protein-based Influenza Vaccine-A Faster Way to Combat the Influenza Pandemic
Dr. Keyang Wang, Scientist, Protein Sciences Corporation, USA

09:30-09:55

Title: Development and Evaluation of a Novel Technology for Intradermal Delivery of Influenza Vaccines
Dr. Chinglai Yang, Assistant Professor, Department of Microbiology and Immunology, Emory University, USA

09:55-10:20

Title: Development of ELISA-based Laboratory Test for Sensitive and Specific SARS Virus Detection
Dr. Kotaro Fujimoto, Chief Researcher, Research and Development Division, Sysmex Co. Ltd., Japan

10:20-10:35

Coffee Break

10:35-11:00

Title: Efficacious Recombinant Avian Flu Vaccine Produced By High Yield Bacterial Expression
Dr. Langzhou Song, Senior Research Scientist, Department of Molecular Biology and Protein Science, Group Leader, VaxInnate Corporation, USA

11:00-11:25

Title: High-throughput Sequencing Pipeline for Complete Influenza A Viral Genomes from Clinical Samples: Nucleotide Polymporphisms, Antiviral Resistance, Ultra-Depth Sequencing Coverage and Clinical Relevance
Dr. Huoshu Houng, Research Microbiologist, Walter Reed Army Institute of Research, USA

11:25-11:50

Discussion