Session Chair:

Dr. Makobetsa Khati, Research Group Leader, Drug Discovery and Development Competency Area, CSIR Biosciences, South Africa

Co-Chair:

Dr. Syed N. Kabir, Deputy Director & Head, Reproductive Biology Research, Indian Institute of ChemicalBiology, India

10:20-10:40

Title: A Synthetic Derivative of gp120 Binding RNA Aptamer Inhibits Entry of Human Immunodeficiency Virus Type 1 Subtype C Isolates
Dr. Makobetsa Khati, Research Group Leader, Drug Discovery and Development Competency Area, CSIR Biosciences, South Africa

10:40-11:00

Title: Acaciaside B-enriched Fraction of Acacia Auriculiformis: A Dual Action Topical Microbicide with Wide Safety Margin.
Dr. Syed N. Kabir, Deputy Director & Head, Reproductive Biology Research, Indian Institute of Chemical Biology, India

Session Chair:

Dr. Thierry Langer, CEO, Prestwick Chemical, Inc., France

11:10-11:30

Title: In Silico Ligand Profiling Using Parallel Pharmacophore-based Virtual Screening: Antiviral Examples
Dr. Thierry Langer, CEO, Prestwick Chemical, Inc., France

11:30-11:50

Title: A Proposed Structure of Modified Nucleoside Expected to Have High Antiviral Activity and Low Toxicity
Dr. Hiroshi Ohrui, Professor, Yokohama College of Pharmacy, Japan

11:50-12:10

Title: "Targeting the RNase H Site of HIV RT": Characterization of an Magnesium-dependent Active RT RNase H for Inhibitor Binding for Drug Screening
Dr. Oscar Leon, Program of Virology, University of Chile, Chile

Session Chair:

Dr. Karl Goodkin, Professor & Director, University of California at Los Angeles, USA

 Co-Chair:

Dr. Xu Guang Xi, CNRS, Institut Curie Centre Universitaire, France

13:30-13:55

Title: The Implications of the Long-term Use of the Protease Inhibitors for HIV-associated Neurocognitive Disorder
Dr. Karl Goodkin, Professor & Director, University of California at Los Angeles, USA

13:55-14:20

Title: Reduction of MRP1 Transporter Protein and mRNA Expression in Blood Cells Isolated from Healthy Volunteers Taking Darunavir/Ritonavir
Dr. Lawrence S. Lee, Academic Consultant, National Healthcare Group, Singapore

14:20-14:45

Title: Helicases as Antiviral and Anticancer Drug Targets
Dr. Xu Guang Xi, CNRS, Institut Curie Centre Universitaire, France

Session Chair:

Dr. David Jans, Professor, Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Australia

09:00-09:20

Title: A Novel Methodology to Identify Potential Anti-viral Agents
Dr. David Jans, Professor, Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Australia

09:20-09:40

Title: Targeting Drug Discovery Catalyzed by 3D HIV-Integrease Model
Dr. Ashoke Sharon, Senior Lecturer, Birla Institute of Technology, India

Session Chair:

Dr. Roland Marquet, Director, University of Strasbourg, CNRS, France

09:40-10:00

Title: Synthesis and Anti-HIV Activity of 1-Substituted 3-(3,5-Dimethylbenzyl) Uracil Derivatives
Dr. Tokumi Maruyama, Professor, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Japan

10:00-10:20

Title: Using Multi-scale in silico Modelling to Understand Antimicrobial Pharmacodynamics: An Example with Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV Treatment
Dr. Max von Kleist, Group Leader, Computational Pharmacokinetics, Free University Berlin, Germany

10:20-10:30

Coffee Break

10:30-10:50

Title: Synthesis and Anti HIV-1 Activity of Mutagenic Nucleosides
Dr. Roland Marquet, Director, CNRS-University of Strasbourg, France

Session Chair:

Dr. Manfred Beilharz, Associate Professor, University of Western Australia, Australia

Co-Chair:

Dr. Oliver H. J. Szolar, CSO, Savira Pharmaceuticals, Austria

13:30-13:50

Title: Low Dose Oral Type 1 IFN: A New Defense against Colds and Flu
Dr. Manfred Beilharz, Associate Professor, University of Western Australia, Australia

13:50-14:10

Title: Exploration of New Anti-Influenza Drugs
Dr. Jim-Min Fang, Distinguished Professor, Department of Chemistry, National Taiwan University, Taiwan

14:10-14:30

Title: High Throughput Screening Approach to Antiviral Discovery : Community Wide Strategy, MLPCN
Dr. Donghoon Chung, Assistant Professor, University of Louisville, USA

14:30-14:50

Title: Novel Anti-Influenza Compounds Active in vitro and in vivo against Pandemic Influenza
Dr. Vladimir V. Zarubaev, Head, Laboratory of Molecular Anti-Viral Chemotherapy, Influenza Research Institute, Russian Academy of Medical Sciences, Russia

14:50-15:10

Title: Conserved Differences between Neuraminidase of Avian Influenza A/H5N1 and Human
Influenza A/H1N1(2009) Affect Binding and Sensitivity to Oseltamivir
Dr. Suganya Yongkiettrakul, Research Scientist, Protein-Ligand Engineering and Molecular Biology Laboratory, BIOTEC Central Research Unit, National Science and Technology Development Agency, Thailand

15:10-15:30

Coffee Break

15:30-15:50

Title: Anti-influenza Virus Activity of Diarylheptanoids Isolated from Alpinia Officinarum in Vitro and Their Efficacies in Mice
Dr. Masahiko Kurokawa, Professor, Department of Biochemistry, School of Pharmaceutical Sciences, Kyushu University of Health and Welfare, Japan

15:50-16:10

Title: Natural Polyphenolic Substances as Potential Antiviral Drugs
Dr. Yi-fei Wang, Professor, Biomedicine Research and Development Center of Jinan University, China

16:10-16:30

Title: High Expression of Avian Influenza A/H5N1 Neuraminidase Head Domain in Mammalian Cells
Dr. Tarangsri Nivitchanyong, Researcher, Virology and Cell Technology Laboratory, National Center for Genetic Engineering and Biotechnology, Thailand

16:30-16:50

Title: Anti Avian Flu Drug Discovery Based on Neuraminidase (NA) as Target
Dr. Wenfang Xu, Director & Professor, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, China

Session Chair:

Dr. Majid Mehtali, Managing Director, Chief Scientific Officer, VIVALIS, France

15:30-15:50

Title: Discovery and Profiling of Original Anti-hepatitis C Small Molecule Inhibitors Targeting NS5b and NS3 Using the 3D-SCREENTM Technology
Dr. Majid Mehtali, Managing Director, Chief Scientific Officer, VIVALIS, France

15:50-16:10

Title: Different in silico Approaches for Hepatitis Virus Therapies: Optimizing siRNA as Gene Therapy and Docking Studies of Novel Benzimidazole Derivatives
Dr. Mahmoud El Hefnawi, Coordinator, Biomedical Informatics and Chemoinformatics Group, National Research Centre, Egypt

Session Chair:

Dr. Majid Mehtali, Managing Director, Chief Scientific Officer, VIVALIS, France

16:10-16:30

Title: Adenovirus Dodecahedron, Universal Delivery Vector
Dr. Jadwiga Chroboczek, Head, Institute of Structural Biology, France

Session Chair:

Dr. Wilbur H. Chen, Assistant Professor, Center for Vaccine Development, University of Maryland School of Medicine, USA

09:00-09:30

Title: Strategies for Overcoming Immunesenescence with Next-generation Influenza Vaccines
Dr. Wilbur H. Chen, Assistant Professor, Center for Vaccine Development, University of Maryland School of Medicine, USA

09:30-10:00

Title: 2009 H1N1 Pandemic Influenza Virus-like Particle Vaccine Efficacy
Dr. Fu-Shi Quan, Research Scientist, Microbiology & Immunology, Emory University School of Medicine, Zetra Biologicals, LLC, USA

10:00-10:30

Coffee Break

  Session Chair:

Dr. Jae-Won Oh, Professor, Department of Pediatrics, College of Medicine, Hanyang University, Korea

10:30-10:55

Title: Human Viral Challenge Studies; Accelerating Proof of Concept for Antivirals against Respiratory Viruses
Dr. Robert Lambkin-Williams, CEO, Retroscreen Virology Limited, UK

10:55-11:20

Title: A Survey of Patients with Severe RSV Infection (2003~2007) in Kyoto Prefecture
Dr. Hisato Ito, Director, Department of Pediatrics, Nantan General Hospital, Japan

11:20-11:45

Title: DNA and Protein Engineered Vaccines Containing a Hemagglutinin Peptide and a scFv CD21-specific Antibody Induce Humoral and CTL Response to Influnza Virus
Dr. Andrey Tchorbanov, Associate Professor, Bulgarian Academy of Sciences, Bulgaria

11:45-12:05

Title: Engineered Meganucleases as a Novel Class of Antiviral Agents
Dr. Roman Galetto, Project Leader, Cellectis Genome Surgery, France