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Chapter 2: Breaking Research and Tech Development in Modern Vaccinology 
-New Thoughts, New Wave, New Methods and New Gateway for Success

Section 2-1-1: Infectious Immunology, Immunity and Vaccinology
Time: 15:30-17:30, March 23, 2011 (Wednesday)
Place: Room No. 212A, 2F, CNCC

Chair:

Dr. Jo-Anne R. Dillon, Professor & Dean, Vaccine and Infectious Disease Organization, University of Saskatchewan, Canada

Co-Chair:

Dr. Ramaswamy Kalyanasundaram, Professor & Head, University of Illinois, USA

15:30-15:50

Title: Qualitative and Quantitative Analyses of Virtually All Subtypes of Influenza A and B Viral Neuraminidases Using Antibodies Targeting the Universally Conserved Sequences
Dr. Runtao He, Head, Public Health Agency of Canada, Canada

15:50-16:10

Title: High Levels of Maternal IgG anti-Vi  Affect Infant’s Antibody Response to Vi Conjugate Vaccine
Dr. Feng-Ying (Kimi) C. Lin, Medical Officer, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, USA

16:10-16:30

Title: Virulence Studies on Cell Division Mutants of Neisseria Gonorrhoeae and Enterohemorrhagic Escherichia Coli
Dr. Jo-Anne R. Dillon, Professor & Dean, Vaccine and Infectious Disease Organization, University of Saskatchewan, Canada

16:30-16:50

Title: SIR2-deficient Leishmania Infantum Induces a Cytokine Profile That Correlates with Protection
Dr. Anabela Cordeiro-da-Silva, Professor & Director, Parasite Disease Group, Institute of Cell and Molecular Biology, Portugal

16:50-17:10

Title: Multivalent Vaccine Approach for Lymphatic Filariasis
Dr. Ramaswamy Kalyanasundaram, Professor & Head, University of Illinois, USA

17:10-17:30

Title: Vitamin D Supplementation for the Prevention of Acute Respiratory Tract Infection: A Randomized Double-blinded Trial among Young Finnish Men 
Dr. Ilkka T Laaksi, Researcher, Department of Cell Biology, Medical School, University of Tampere, Finland

Section 2-1-2: Innate Immunity, Mucosal Immunity and Novel Vaccines
Time: 15:30-17:50, March 23, 2011 (Wednesday)
Place: Room No. 211, 2F, CNCC

Chair: 

Dr. Kejian Yang, Vice President, Virology and Vaccine, Biomedical Research Models, Inc., USA

Co-Chair: 

Dr. Bernard P Arulanandam, Professor & Associate Dean, Department of Microbiology & Immunology, University of Texas at San Antonio, USA

15:30-15:50

Title: Bacterium-like Particles and Their Role as Adjuvants in Mucosal Vaccines
Dr.
Govert J. Schouten, CEO, Mucosis B.V., The Netherlands

15:50-16:10

Title: A Mucosal Vaccination Approach for Herpes Simplex Virus Type-2
Dr. Kejian Yang, Vice President, Virology and Vaccine, Biomedical Research Models, Inc., USA

16:10-16:30

Title: A Mucosal Vaccine against Chlamydia Trachomatis
Dr. Bernard P Arulanandam, Professor & Associate Dean, Department of Microbiology & Immunology, University of Texas at San Antonio, USA

16:30-16:50

Title: Oral Administration of High Molecular Weight Hyaluronan (900 kDa) Controls Immune System Via Toll-like Receptor 4 in the Intestinal Epithelium
Dr. Akira Asari, President, CEO & CSO, Hyaluronan Research Institute (HRI), Japan

16:50-17:10

Title: A Newcastle Disease Virus based Virus-like Particle Chimera Vaccine against Human Respiratory Syncytial Virus
Dr. Matthew R. Murawski, Scientist, Stemcell Technologies, Canada

17:10-17:30

Title: Innate Immune Recognition of Neisseria Meningitidis Capsular Polysaccharides
Dr. Susu M Zughaier, Research Assistant Professor, Emory University School of Medicine, USA

17:30-17:50

Title: The Uniqueness of Mucosa-associated Lymphoid Tissues for the Development of Mucosal Vaccine
Dr. Jun Kunisawa, LecturerInstitute of Medical Science, The University of Tokyo, Japan


Part 2.2: Novel Vaccine Discovery Technology

Section 2-2-1: Bioinformatics, Antigen Design, and Vaccine Development
Time: 13:30-15:30, March 23, 2011 (Wednesday)
Place: Room No. 210B, 2F, CNCC

Chair:

Dr. Vidadi M. Yusibov, Executive Director, Fraunhofer USA Center for Molecular Biotechnology, USA

Co-Chair:

Dr. Yongqun ”Oliver” He, Assistant Professor, University of Michigan Medical School, USA

13:30-13:55

Title: VLP-based Vaccine against Malaria
Dr. Vidadi M. Yusibov,
Executive Director, Fraunhofer USA Center for Molecular Biotechnology, USA

13:55-14:20

Title: Computational Antibody Vaccine Discovery by Conformational Epitope Prediction and Design of Novel Protein Scaffolds
Dr. Vaikuntanath Samudrala,
Associate Professor, Computational Biology Group, University of Washington, USA

14:20-14:45

Title: Systematic Analysis of Vaccine Targets of Bacterial Pathogens Using Vaxign Reverse Vaccinology
Dr. Yongqun ”Oliver” He, Assistant Professor, University of Michigan Medical School, USA

14:45-15:10

Title: Decoding Non-coding Dna Codes: Human Genome Meta-chromosomes Architecture
Dr. Jean-Claude Perez,
Individual Researcher, Bordeaux, France
(support from Pr Luc Montagnier FMPRS World AIDS Foundation UNESCO and Jean-rené Fourtou Vivendi Universal chairman)

15:10-15:30

Coffee Break

Section 2-2-2: DNA Based Vaccines and Technologies
Time: 13:30-14:45, March 23, 2011 (Wednesday)
Place: Room No. 211, 2F, CNCC

Chair:
 

Dr. Daniel Scherman, Director, Centre National de la Recherche Scientifique (CNRS) / National Scientific Research Center, France

Co-Chair:

Dr. Dinesh K. Singh, Associate Professor, Winston-Salem State University, USA

13:30-13:55

Title: Generation of High-Titer Neutralizing Antibodies against Botulinum Toxins A, B, and E by DNA Electrotransfer
Dr. Daniel Scherman,
Director, Centre National de la Recherche Scientifique (CNRS) / National Scientific Research Center, France

13:55-14:20

Title: Human Antibody Engineering for Botulism Prevention and Treatment
Dr. Jianlong Lou, Group Leader, The University of California at San Francisco, USA

14:20-14:45

Title: Use of Recombinant Flagellin to Enhance Mucosal Immunogenicity of a Plasmid SHIV-DNA in Mice
Dr. Dinesh K. Singh,
Associate Professor, Winston-Salem State University, USA

Section 2-2-3: Adjuvants and Vaccine Designs
Time: 08:30-10:55, March 24, 2011 (Thursday)
Place: Room No. 211, 2F, CNCC

Chair:

Dr. Nathalie Garcon, Vice President; Head of Global Adjuvant Center for Vaccines, GlaxoSmithKline Biologicals, Belgium

Co-Chair:

Dr. Wangxue Chen, Senior Research Officer, Institute for Biological Sciences, National Research Council Canada, Canada

08:30-08:55

Title:Adjuvants in Human Vaccines: Selection and Evaluation
Dr. Nathalie Garcon, Vice President; Head of Global Adjuvant Center for Vaccines, GlaxoSmithKline Biologicals, Belgium

08:55-09:20

Title: Potent Novel mRNA Based Vaccines and Adjuvants
Dr. Ingmar Hoerr, CEO & Co-founder, CureVac GmbH, Germany

09:20-09:45

Title: A New Class of Lipidic Immunomodulators that Activate TLR-dependent Cascades and Cytokine Secretion
Dr. Jean-Marie Ruysschaert, Professor, Center of Structural Biology and Bioinformatics, Belgium

09:45-10:10

Title: αGalcer as Adjuvant? Lesson from Chlamydial Research
Dr. Xi Yang, Professor, Department of Medical Microbiology, University of Manitoba, Canada

10:10-10:30

Coffee Break

10:30-10:55

Title: The Potential of 3’,5’-cyclic Diguanylic Acid (c-di-GMP) as an Effective Vaccine Adjuvant
Dr. Wangxue Chen
, Senior Research Officer, Institute for Biological Sciences, National Research Council Canada, Canada



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