BIT’s 3rd Symposium on
Enzymes and Biocatalysis 2012
Theme: Design Robust Enzymes in a New Era
Time: April 25-28, 2012
Place: Qujiang International Conference Center (QICC), Xi'an, China
Nobel Laureates Forum (Part I)
April 25, 2012 (Wednesday)
Time: 09:30-11:40; Place: Qujiang Auditorium, 3rd Floor, QICC |
Moderator: |
Dr. Richard Roberts, Chief Scientific Officer, New England Biolabs, USA |
09:30-09:35 |
Chair’s Introduction |
09:35-10:00 |
Title: Visions of Stem Cells
Dr. Martin J. Evans, Director, Cardiff University, UK, Nobel Prize Laureate in Physiology/Medicine 2007 |
10:00-10:25 |
Title: Structural Insights into DNA Replication by the Replisome and Transcription by T7 RNA Polymerase
Dr. Thomas Steitz, Professor, Yale University, USA, Nobel Prize Laureate in Chemistry 2009 |
10:25-10:50 |
Title: COMBREX - Genomes, Computers and Experimentation in Biology
Dr. Richard Roberts, Chief Scientific Officer, New England Biolabs, USA, Nobel Prize Laureate in Physiology/Medicine 1993 |
10:50-11:15 |
Title: Discovering Helicobacter
Dr. J. Robin Warren, Pathologist, Royal Perth Hospital, Australia, Nobel Prize Laureate in Physiology/Medicine 2005 |
11:15-11:40 |
Title: Membrane Proteins: Importance, Structures, Mechanisms
Dr. Hartmut Michel, Professor, Max Planck Institute of Biophysics, Germany, Nobel Prize Laureate in Chemistry 1988 |
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Keynote Forum
April 25, 2012 (Wednesday)
Time: 13:30-16:10; Place: Room 313, 3rd Floor, QICC |
Moderator: |
Dr. Junhua (Alex) Tao, CEO, Metabomics, Inc., China |
13:30-13:40 |
Moderator's Introduction |
13:40-14:10 |
Title: Industrial Enzyme Applications – A Future Perspective
Mr. Erik Gormsen, Vice President, Applied Discovery, Novozymes A/S, Denmark |
14:10-14:40 |
Title: The New DuPont Industrial Biosciences: Building from Genencor’s Industrial Enzyme Business
Dr. Aaron Kelley, Regional Marketing Director, Asia Pacific, Genencor, DuPont Industrial Biosciences, China |
14:40-15:10 |
Title: Add Life to Chemistry
Dr. Junhua (Alex) Tao, CEO, Metabomics, Inc., China |
15:10-15:40 |
Title: Better Enzymes En-route—Probing the Fidelity Determination in Type II Restriction Endonucleases
Dr. Dapeng Sun, General Manager, New England Biolabs, Shanghai R&D Center, China |
15:40-16:10 |
Title:Biocatalysis in Agricultural Biotechnology
Dr. Jei-Fu Shaw, Chair Professor and President, I-Shou University, Taiwan |
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Track 1: New Enzyme Discovery and Activity Optimizations
SEB 100: New Enzyme Discovery and Activity Optimizations
Time: 08:30-10:30, April 26, 2012 (Thursday); Place: Meeting Room 205, 2nd Floor, QICC |
Chair: |
Dr. Kenji Ikehara, Director & Professor, Nara Study Center, The Open University, Japan; Fellow, International Institute for Advanced Studies, Japan; Emeritus Professor, Nara Women’s University, Japan |
08:30-08:35 |
Chair’s Introduction |
08:35-09:10 |
Title: Engineering Plant Polyketide Synthases
Dr. Ikuro Abe, Professor, The University of Tokyo, Japan |
09:10-09:45 |
Title: The Interaction of Silver Nanoparticles with Superoxide Dismutase from Human and Plasmodium Parasite: A Comparitive Study
Dr. Chris Whiteley, Professor, Department of Biochemistry, Microbiology & Biotechnology, Rhodes University, South Africa |
09:45-10:20 |
Title: Creation and Development of Entirely New Enzymes
Dr. Kenji Ikehara, Director & Professor, Nara Study Center, The Open University, Japan; Fellow, International Institute for Advanced Studies, Japan; Emeritus Professor, Nara Women’s University, Japan |
10:20-10:30 |
Coffee Break |
Track 2: Breaking Research and Technologies of Enzyme and Biocatalysis
SEB 200: Enzyme Structure, Functionality Screening and Regulations
Time: 10:30-12:15, April 26, 2012 (Thursday); Place: Meeting Room 205, 2nd Floor, QICC |
Chair: |
Dr. Willem J. H. van Berkel, Professor, Wageningen University, The Netherlands |
10:30-10:35 |
Chair’s Introduction |
10:35-11:00 |
Title: Substrate and Reaction Specificities of Enzyme: A Case of Pseudomanas L-Phenylalanine Oxidase
Dr. Haruo Suzuki, Professor Emeritus, Kitasato University, Japan |
11:00-11:25 |
Title: Surface-sensitive X-ray Scattering as a Tool to Investigate Enzymatic Reactions
Dr. Ronald Gebhardt, Scientist, Technische Universität München, TUM, Germany |
11:25-11:50 |
Title: Design of Nylon Oligomer Hydrolase on the Basis of Simulations
Dr. Yasuteru Shigeta, Associate Professor, Osaka University, Japan |
11:50-12:15 |
Title: Optimization Flavoprotein Monooxygenases
Dr. Willem J. H. van Berkel, Professor, Wageningen University, The Netherlands |
SEB 201: Enzyme Stabilization, Immobilization and Encapsulatio
Time: 13:30-15:30, April 26, 2012 (Thursday); Place: Meeting Room 205, 2nd Floor, QICC |
Chair: |
Dr. Rosa M. Blanco, Tenured Scientist, Instituto de Catalisis. CSIC, Spain |
13:30-13:35 |
Chair’s Introduction |
13:35-14:10 |
Title: Design of Two Coimmobilized Biocatalysts and Integration in a Reaction System with Integrated Product Separation
Dr. Hans-Joachim Jördening, Professor, Technische Universtität Braunschweig, Germany |
14:10-14:45 |
Title: LiCl-induced Improvement of Multilayer Bioactive Nanofibers for Biosynthesis
Dr. Songping Zhang, Associate Researcher, National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, CAS, China |
14:45-15:20 |
Title: New Focusing of Silica, Hydrophobicity and Lipase as the Key to Obtain Advanced Biocatalysts
Dr. Rosa M. Blanco, Tenured Scientist, Instituto de Catálisis. CSIC, Spain |
15:20-15:30 |
Coffee Break |
SEB 202: Multi-scale Quantum Models for Biocatalysis
Time: 08:30-09:35, April 27, 2012 (Friday); Place: Meeting Room 205, 2nd Floor, QICC |
Chair: |
Dr. Piotr Paneth, Professor, Technical University of Lodz, Poland |
Co-Chair: |
Dr. David M. Smith, Assistant Director, Rudjer Boskovic Institute, Croatia |
08:30-08:35 |
Chair’s Introduction |
08:35-08:55 |
Title: Proton Transfer Dynamics in Strong Hydrogen Bonded Systems
Dr. Zdzislaw Latajka, Professor, Faculty of Chemistry, University of Wroclaw, Poland |
08:55-09:15 |
Title: The Elusive 5'-Deoxyadenosyl Radical in Coenzyme-B12-Mediated Reactions
Dr. David M. Smith, Assistant Director, Rudjer Boskovic Institute, Croatia |
09:15-09:35 |
Title: Determination of Mechanisms of Enzymatic Dehalogenations Using Chlorine Kinetic Isotope Effects
Dr. Piotr Paneth, Professor, Technical University of Lodz, Poland |
SEB 203: Other Innovation of Enzyme and Biocatalysis
Time: 09:35-11:50 April 27, 2012 (Friday); Place: Meeting Room 205, 2nd Floor, QICC |
Chair: |
Dr. Kesen Ma, Associate Professor, University of Waterloo, Canada |
09:35-09:40 |
Chair’s Introduction |
09:40-10:00 |
Title: Artificial Enzyme Design Based on Photoreactive Biomimetic Systems
Dr. Günther Knör, Professor, Institute of Inorganic Chemistry, University of Linz, Austria |
10:00-10:20 |
Title: Novel Self-oscillating Polymer Actuators with Ru(Bpy)3 Catalyst
Dr. Yusuke Hara, Researcher, Nanosystem Research Institute (NRI), National Institute of Advanced Industrial Science and Technology (AIST), Japan |
10:20-10:30 |
Coffee Break |
10:30-10:50 |
Title: Industrial Enzyme Production, A Rational Approach towards Yield Improvement
Dr. Hans van den Brink, Head of Enzymes Department, Innovation, Chr. Hansen A/S, Denmark |
10:50-11:10 |
Title: Production of Lignin Peroxidase from Sparassis crispa Mushroom and Their Biodegradation Aspects on Single-walled Carbon Nanotubes
Dr. Hyun-Jae Shin, Assistant Professor, Chosun University, South Korea |
11:10-11:30 |
Title: Functionalized Graphene as Biosensors
Dr. Yong Liu, Assistant Director, Wenzhou Medical College, China |
11:30-11:50 |
Title: Thermostable Decarboxylases of Hyperthermophiles
Dr. Kesen Ma, Associate Professor, University of Waterloo, Canada |
Track 3: Enzymes/Biocatalysis for Pharmaceutical and Medical Industry
SEB 300: Enzymes in Pharmaceutical Industry
Time: 08:30-10:30 April 26, 2012 (Thursday) ; Place: Meeting Room 206, 2nd Floor, QICC |
Chair: |
Dr. David T. Chuang, Professor, University of Texas Southwestern Medical Center, USA |
Co-Chair: |
Dr. Cheng-Xin Gong, Senior Research Scientist, New York State Institute for Basic Research in Developmental Disabilities, USA |
08:30-08:35 |
Chair’s Introduction |
08:35-08:55 |
Title: Next Generation Kinase Knowledge Platform: An Integrated Solution for Drug Discovery
Dr. Fabio Ferfoglia, Knowledge Management Scientist, Merck Serono, Switzerland |
08:55-09:15 |
Title: Enzymes for Pancreatic Replacement Therapy: Challenges for Standardization and Quality
Dr. Jo Demeester, Professor & Director, Laboratory of General Biochemistry and Physical Pharmacy, Ghent University, Belgium |
09:15-09:35 |
Title: Enzymatic Drug Targets for Alzheimer's Disease
Dr. Cheng-Xin Gong, Senior Research Scientist, New York State Institute for Basic Research in Developmental Disabilities, USA |
09:35-09:55 |
Title: DNA-Pkcs-Topoisomerase I Interaction as a Target for the Potentiation of Camptothecins
Dr. Pourquier Philippe, Group Leader, INSERM U916, Bordeaux Ségalen University & Bergonié Cancer Center, France |
09:55-10:15 |
Title: Targeting Mitochondrial Protein Kinases for Cancer and Metabolic Diseases
Dr. David T. Chuang, Professor, University of Texas Southwestern Medical Center, USA |
10:15-10:30 |
Coffee Break |
SEB 301: Medical Enzymes
Time: 15:30-17:15, April 26, 2012 (Tuesday) ; Place: Meeting Room 205, 2nd Floor, QICC |
Chair: |
Dr. Eminy H. Y. Lee, Distinguished Research Fellow, Institute of Biomedical Sciences, Academia Sinica, Taiwan |
Co-Chair: |
Dr. Zuzana Bilkova, Associate Professor, University of Pardubice, Czech Republic |
15:30-15:35 |
Chair’s Introduction |
15:35-15:55 |
Title: Environmental Biosensing Based on Enzyme Inhibition
Dr. Marek Trojanowicz, Professor of Analytical Chemistry, University of Warsaw, Poland |
15:55-16:15 |
Title: Single Molecule Sensitive Chemiluminescent Amplification Technology
Dr. Chong Yuan, Chairman, Shanghai Daizyme, China |
16:15-16:35 |
Title: Mechanism and Possible Molecular Role of a Metallopeptidase Involved in the Pathology of Mycobacterium Tuberculosis
Dr. Massimiliano Coletta, Professor, University of Roma Tor Vergata, Italy |
16:35-16:55 |
Title: Magnetic Particles-based Techniques: Possibilities and Limitations
Dr. Zuzana Bilkova, Associate Professor, University of Pardubice, Czech Republic |
16:55-17:15 |
Title: ERK/MAPK and SGK1 Signaling Mediates the Memory-Impairing Effect of Laminin ß1
Dr. Eminy H. Y. Lee, Distinguished Research Fellow, Institute of Biomedical Sciences, Academia Sinica, Taiwan |
Track 4: Applied Industrial Enzymes
SEB 400: Enzymes for Animal Feeds
Time: 10:30-11:50, April 26, 2012 (Thursday) ; Place: Meeting Room 206, 2nd Floor, QICC |
Chair: |
Dr. Yingyao Wang, Associate Professor, Academy of State Administration of Grain, China |
10:30-10:35 |
Chair’s Introduction |
10:35-11:00 |
Title: A New Generation of Enzymes for Improving the Nutritive Value of Cereal Grains in Animal Feed
Dr. Dan Pettersson, Science Manager, Department of Feed Applications, Novozymes A/S, Denmark |
11:00-11:25 |
Title: Lipase-Catalyzed Acidolysis of Canola Oil with Caprylic Acid to Produce Medium-, Long- and Medium-Chain-type Structured Lipids
Dr. Yingyao Wang, Associate Professor, Academy of State Administration of Grain, China |
11:25-11:50 |
Title: RONOZYME® Phytase – An Environmentally Friendly Alternative to Inorganic Phosphorous in Pig and Poultry Feed
Mr. R. K. Nagaraju, Life Cycle Assessment Specialist, Novozymes South Asia Private Limited, India |
SEB 401: Other Enzymatic Uses
Time: 08:30-12:10, April 27, 2012 (Friday) ; Place: Meeting Room 206, 2nd Floor, QICC |
Chair: |
Ms. Janet Roemer, Chief Operating Officer, Verenium Corporation, USA |
Co-Chair: |
Dr. Kasipathy Kailasapathy, Professor, Taylor's University, Malaysia |
08:30-08:35 |
Chair’s Introduction |
08:35-08:55 |
Title: Enzyme Stability in Household Liquid Detergents - Use of Differential Scanning Calorimetry
Dr. Henrik Lund, Research Scientist, Novozymes A/S, Denmark |
08:55-09:15 |
Title: Plant Peroxidases in the Determination of Their Organic Substrates in Water, Water-organic Media, And Ionic Liquids
Dr. Tatyana Shekhovtsova, Professor, M.V. Lomonosov Moscow State University, Russia |
09:15-09:35 |
Title: Structure and Function of Some Enzymes for Carbohydrate Digestion and Metabolism
Dr. Ei-ichiro Suzuki, Executive Fellow, Ajinomoto Co., Inc., Japan |
09:35-09:55 |
Title: Improving Nature's Enzyme Repertoire for Food, Biofuel and Pharma Production
Dr. Rene de Jong, Scientist Applied Biochemistry, DSM Biotechnology Center, The Netherlands |
09:55-10:15 |
Title: Enzymes for Oil & Gas Production – Effective, Economic and Better for the Environment
Ms. Janet Roemer, Chief Operating Officer, Verenium Corporation, USA |
10:15-10:30 |
Coffee Break |
10:30-10:50 |
Title: Encapsulation and Controlled Delivery of Enzymes in Food Processing
Dr. Kasipathy Kailasapathy, Professor, Taylor's University, Malaysia |
10:50-11:10 |
Title: Enzyme Stabilization in Detergents by Formulation
Dr. Robert Pieter van der Lans, Manager Formulation Development China, Novozymes (China) Biotechnology Co., Ltd., China |
11:10-11:30 |
Title: Leaf Cutter Ants Digestive Enzymes: Biological and Technical Applications
Dr. Milton Erthal Junior, Professor, Fluminense Federal Institute, Brazil |
11:30-11:50 |
Title: A Rapid Technology of Herbaceous Fibre Bio-extracting
Dr. Zhengchu Liu, Professor, Institute of Bast Fiber Crops (IBFC), Chinese Academy of Agricultural Science (CAAS), China |
11:50-12:10 |
Title: Bioactive Peptides from Fish Skin Collagen
Dr. Maggy Thenawidjaja Suhartono, Professor, Department of Food Science & Technology, Bogor Agricultural University, Indonesia |
SEB 402: Trend and Applications of Industrial Enzymes
Time:10:50-12:10, April 28, 2012 (Saturday) ; Place: Meeting Room 313A, 3rd Floor, QICC |
Chair: |
Dr. Nathalie Berezina, R&D Scientist, Materia Nova R&D Centre, Belgium |
10:50-10:55 |
Chair’s Introduction |
10:55-11:20 |
Title: Lipase Applications in Fat and Oleochemical Industry: Modification of Fats and Oils
Dr. H. Ayse Aksoy, Professor, Istanbul Technical University, Turkey |
11:20-11:45 |
Title: Molecular Mechanism of Glycosylases Catalyzing Megalosaccharide Production
Dr. Atsuo Kimura, Professor, Hokkaido University, Japan |
11:45-12:10 |
Title: Enzymes in Non Conventional Media
Dr. Nathalie Berezina, R&D Scientist, Materia Nova R&D Centre, Belgium |
Track 5: Biocatalysis and Bioenergy
SEB 500: Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes
Time:13:30-16:20, April 26, 2012 (Thursday) ; Place: Meeting Room 206, 2nd Floor, QICC |
Chair: |
Dr. Lew Christopher, Professor and Director, Center for Bioprocessing Research & Development, South Dakota School of Mines and Technology, USA |
13:30-13:35 |
Chair’s Introduction |
13:35-14:00 |
Title: Development of Enzyme Systems for Saccharification of Lignocellulosic Feedstocks
Ms. Amy Liu, Scientist, Genencor, DuPont Industrial Biosciences, USA |
14:00-14:25 |
Title: A Novel Endoglucanase Produced by a Fungal Pathogen of Tomato Involved in Cellulose Degradation
Dr. Maria Aragona, Researcher, Plant Pathology Research Centre, Agriculture Research Council (CRA), Italy |
14:25-14:50 |
Title: Enzyme Discovery for Deconstruction of Lignocellulosic Materials in Production of Biofuel
Dr. I-Son Ng, Associate Professor, Department of Chemical and Biochemical Engineering, Xiamen University, China |
14:50-15:15 |
Title: Effect of the Binding Modules on the Activities of Cellulases and Xylanases
Dr. M. Waheed Akhtar, Director, School of Biological Sciences, University of the Punjab, Pakistan |
15:15-15:30 |
Coffee Break |
15:30-15:55 |
Title: Exploitation of Thermophilic Cellulases for Improved Ethanol Production from Lignocellulosic Biomass
Dr. Lew Christopher, Professor and Director, Center for Bioprocessing Research & Development, South Dakota School of Mines and Technology, USA |
15:55-16:20 |
Title: Screening of Microorganisms from Brazilian Cerrado Areas with Industrial Potential Production of Amylases, Celulases and Hemicelulases
Dr. Heloiza Ferreira Alves do Prado, Professor, University Estadual Paulista – UNESP, Faculdade de Engenharia, Campus Ilha Solteira, Brazil |
SEB 501: Enzymes for Biofuel Production
Time:08:30-10:50, April 28, 2012 (Saturday) ; Place: Meeting Room 313A, 3rd Floor, QICC |
Chair: |
Dr. Kasiviswanath Muthukumarappan, Professor, South Dakota State University, USA |
Co-Chair: |
Dr. Zhen Yang, Professor, Shenzhen University, China |
08:30-08:35 |
Chair’s Introduction |
08:35-08:55 |
Title: Diversity of Substrate Recognition by Microbial Endo-ß-1, 4-xylanases
Dr. Peter Biely, Research Professor, Institute of Chemistry, Slovak Academy of Sciences, Slovakia |
08:55-09:15 |
Title: Extremophilic NiFe Hydrogenase Immobilization on Electrodes for H2/O2 Biofuel Cell Development
Dr. Elisabeth Lojou, Professor, CNRS – Bioénergétique et Ingénierie des Protéines, France |
09:15-09:35 |
Title: Evaluation of Different Pretreated Biomass Materials by Cellic Ctec Product
Dr. Dongmin Li, Senior Research Scientist, Novozymes (China) Investment Co. Ltd., China |
09:35-09:55 |
Title: Selection of Enzyme Combination, Dose and Temperature for Hydrolysis of Soybean White Flakes
Dr. Kasiviswanath Muthukumarappan, Professor, South Dakota State University, USA |
09:55-10:15 |
Title: Enzymatic Production of Biodiesel in Ionic Liquids
Dr. Zhen Yang, Professor, Shenzhen University, China |
10:15-10:30 |
Coffee Break |
10:30-10:50 |
Title: New Techniques of Biodiesel Production Catalyzed by Combined Lipases and Development of Its High Value-added Chemicals
Dr. Yunjun Yan, Director, Key Laboratory of Molecular Biophysics, Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, China |
Track 6: Biocatalysis and Biotransformations in Organic Synthesis
SEB 600: Biocatalysis and Biotransformations in Organic Synthesis
Time: 16:20-17:25, April 26, 2012 (Thursday) ; Place: Meeting Room 206, 2nd Floor, QICC |
Chair: |
Dr. Hongyue Dang, Professor, China University of Petroleum, China |
16:20-16:25 |
Chair’s Introduction |
16:25-16:45 |
Title: Enzyme-Catalyzed Oxidative Polymerization of Phenolic Glycosides
Dr. Hirofumi Nakano, Senior Research Scientist, Director of Biomaterials and Commodity Chemicals Division, Osaka Municipal Technical Research Institute, Japan |
16:45-17:05 |
Title: Thermophilic Esterases and Recombinant Escherichia Coli Whole-Cell: Novel Biocatalysts for the Synthesis of Biodegradable Polyesters
Dr. Quanshun Li, Associate Professor, Jilin University, China |
17:05-17:25 |
Title: Wheel of Life – Rotational Symmetry in Key Enzymes’ Structure and Function
Dr. Hongyue Dang, Professor, China University of Petroleum (East China), China |
Young Investigator Forum
Time:13:30-16:40, April 27, 2012 (Friday) ; Place: Meeting Room 206, 2nd Floor, QICC |
Chair: |
Mrs. Tozama Ogunleye, Synthetic Chemist, CSIR Biosciences, Protein Technologies Group, South Africa |
13:30-13:35 |
Chair’s Introduction |
13:35-14:10 |
Title: Growth of Streptomyces Mirabilis P16B1 in Heavy Metal Contaminated Soil and Impact to Soil Organic Matter Formation
Ms. Eileen Schütze, Student, Institute for Microbiology - Microbial Phytopathology, Friedrich-Schiller-University, Germany |
14:10-14:45 |
Title: Strategies for Isolation of Novel Enzymes from Extremophiles: A Metagenomics Approach
Havva Esra Bıyık, Ph.D. Student, Istanbul Technical University, Turkey |
14:45-15:20 |
Title: Studies on the Biocatalytic Synthesis of 5, 6-Dihydroxylated Benzo[b]furans and Catechol Derivatives and Their Antibacterial Activity
Mrs. Tozama Ogunleye, Synthetic Chemist, CSIR Biosciences, Protein Technologies Group, South Africa |
15:20-15:30 |
Coffee Break |
15:30-16:05 |
Title: Optimization of Recombinant HcRNAV 109 Capsid Protein in Pichia pastoris and Their Self-assembly into Virus-like Particles
Yuanzheng Wu, Ph.D. Student, Department of Chemical and Biochemical Engineering, Chosun University, South Korea |
16:05-16:40 |
Title: Ethanol Yeast Culture as Nutrient for SSF of L-Lactic Acid Production from Lignocellulic Materials
Dr. Yong Tang, Ph.D. Student, Beijing Forestry University, China |
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