Session 1-1: Advances of Protein Molecular Biology and Cell Biology

(Time: 13:30-14:45, March 23, 2011, Wednesday; Place: Room No. 207, 2F, CNCC)   

Chair

Dr. Evgeny Ivanovich Solenov, Associated Professor, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Russia

13:30-13:55

Keynote Speech:
Title: Protein Damage as the Cause of Aging and Death
Dr. Miroslav Radman, Professor of Cell Biology, University of Paris-5, Member of French Academy of Sciences, France

13:55-14:20

Title: Study of Transduction Mechanism of Vasopressin Antidiuretic Signal in Developing Kidney
Dr. Evgeny Ivanovich Solenov, Associated Professor, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Russia

14:20-14:45

Title: Promiscuous Expression of Cell Surface Proteins in Pluripotent Stem Cells and Germ Cells
Dr. Bin Gu, Professor, Institute of Genetics, College of Life Sciences, Zhejiang University, China

Session 1-2: Protein Folding Dynamics, Stability and Quality Control (Part I )

(Time: 13:30-17:10, March 23, 2011, Wednesday; Place: Room No. 202A, 2F, CNCC) 

Chair:

Dr. Douglas M. Cyr, Professor, Department of Cell Biology, University of North Carolina, USA

Co-Chair:

Dr. Walid A. Houry, Professor, Biochemistry, University of Toronto, Canada

13:30-13:55

Title: Assessment of Protein Folding Dynamics and Stability
Dr. Jiaan Yang, Vice President, Drug Discovery Technology, Sundia MediTech Company, Ltd., China

13:55-14:20

Title: Interplay Between Cytosolic and ER Chaperone Systems in Endoplasmic Reticulum Quality Control (ERQC)
Dr. Douglas M. Cyr, Professor, Department of Cell Biology, University of North Carolina, USA

14:20-14:45

Title: Systematic Mapping of Chaperone Interaction Networks in the Cell Reveals Novel Functions for Chaperones in Cellular Homeostasis
Dr. Walid A. Houry, Professor, Biochemistry, University of Toronto, Canada

14:45-15:10

Title: Protein Folding on the Ribosome: When the Protein Folding Code Meets the Genetic Code
Dr. Anton A. Komar, Associate Professor, Center for Gene Regulation in Health and Disease, Deptartment of Biology, Cleveland State University, USA

15:10-15:30

Coffee Break

15:30-15:55

Title: Prediction of Protein Folding Properties with Analyses of Inter-residue Average Distance Statistics
Dr. Takeshi Kikuchi, Professor, Department of Bioinformatics, College of Life Science, Ritsumeikan University, Japan 

15:55-16:20

Title: Determination of the Folded Structure of Vasoactive Intestinal Peptide Using Molecular Dynamics
Dr. Mduduzi Paulos Mokoena, Durban University of Technology, South Africa

16:20-16:45

Title: Analysis of the Beta-Helical Fold toward Understanding of Amyloid Fibril Structure
Dr. Jay H. Choi, Research Fellow, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, USA  

16:45-17:10

Title: ST1710-DNA Complex Crystal Structure Reveals the DNA Binding Mechanism of the MarR Family of Regulators
Dr. Tomoyuki Tanaka, Reserch Associate, Protein Crystallography Research Group, RIKEN SPring-8 Center, Japan

Session 1-2: Protein Folding Dynamics, Stability and Quality Control (Part II )

(Time: 08:30-10:35, March 25, 2011, Friday; Place: Room No. 202A, 2F, CNCC) 

Chair:

Dr. Wolfgang Voos, Professor, Institute for Biochemistry and Molecular Biology, University of Bonn, Germany  

08:30-08:55

Title: Computational Shotgun Multitarget Drug Discovery using Fragment Based Docking with Dynamics
Dr. Ram Samudrala, Associate Professor, Department of Microbiology, University of Washington, USA

08:55-09:20

Title: Chaperones and Proteases as Mediators of Mitochondrial Protein Homeostasis
Dr. Wolfgang Voos, Professor, Institute for Biochemistry and Molecular Biology, University of Bonn, Germany

09:20-09:45

Title: Specificity of Amino Acid Residue: Dipole Moment and Dispersion Force
Dr. Misako Aida, Director, Center for Quantum Life Sciences, Hiroshima University, Japan

09:45-10:10

Title: Regulated Protein Degradation: Aaa+ Proteases and the Adaptor Proteins that Control Them
Dr. David Dougan, Senior Research Fellow, Department of Biochemistry, La Trobe University, Australia

10:10-10:35

Title: Chemical Machinery for Protein Folding: Molecular Simulation and Experimental Validation
Dr. Zheng Liu, Professor, Department of Chemical Engineering Tsinghua University, China

Session 1-3: Protein-Protein Interactions and Protein-Transduction

(Time: 13:30-16:20, March 23, 2011, Wednesday; Place: Room No. 202B, 2F, CNCC)

Chair:

Dr. Jan Tavernier, Professor & Head, Cytokine Receptor Lab, Belgium

Co-Chair:

Dr. Elena Kashuba, Associate Professor, MTC Karolinska Institute, Sweden 

13:30-13:55

Title: The Far-Western Technique: A Tool for the Search for Insoluble Partner Application to the Screening of S100b Partners
Dr. Denis Rousseau, Director, Universite Joseph Fourier, INSERM, France

13:55-14:20

Title: The MAPPIT Toolbox: Strategies to Analyze Molecular Interactions in Intact Cells
Dr. Jan Tavernier, Professor & Head, Cytokine Receptor Lab, Ghent University, Belgium

14:20-14:45

Title: Binding Activity Analysis of Native-Formed Protein by Light Scattering Technology
Dr. Kohei Shiba, Product Specialist, Malvern Japan Division, Spectris Co., Ltd., Japan

14:45-15:10

Title: Anchors and Cavities in Protein-Protein Recognition
Dr. Miriam Eisenstein, Senior Staff Scientist, Chemical Research Support, Weizmann Institute of Science, Israel

15:10-15:30

Coffee Break

15:30-15:55

Title: EBNA-binding Cellular Proteins and their Role in Cell Transformation
Dr. Elena Kashuba, Associate Professor, MTC Karolinska Institute, Sweden

15:55-16:20

Title: Genome-wide Analyses of Intrinsic Disorder in Protein-protein Interaction Network
Dr. Kana Shimizu, Research Scientist, Computational Biology Research Center, AIST, Japan

Session 1-4: Proteins Interacting with DNA and RNA

(Time: 15:05-17:10, March 23, 2011, Wednesday; Place: Room No. 207, 2F, CNCC) 

Chair:

Dr. Yves Mely, Professor, Laboratory of Biophotonics and Pharmacology, University of Strasbourg, France

Co-Chair:

Dr. Arun Malhotra, Associate Professor, Department of Biochemistry & Molecular Biology, University of Miami School of Medicine, USA

15:05-15:30

Title: Structures and Mechanisms of NanoRNA Degrading Exoribonucleases
Dr. Arun Malhotra, Associate Professor, Department of Biochemistry & Molecular Biology, University of Miami School of Medicine, USA

15:30-15:55

 Title: The Nucleic Acid Chaperone Properties of the HIV-1 nucleocapsid Protein: a Biophysical Approach
Dr. Yves Mely, Professor, Laboratory of Biophotonics and Pharmacology, University of Strasbourg, France

15:55-16:20

Title: Plant Genome Engineering Using Zinc Finger Nucleases (ZFNs)
Dr. Yiping Qi, Research Associtate, Center for Genome Engineering, University of Minnesota, USA

16:20-16:45

Title: Time Resolved Detection of Protein-DNA Interactions for DNA Repair Reaction
Dr. Masahide Terazima, Professor, Department of Chemsitry, Graduate School of Science, Kyoto University, Japan

16:45-17:10

Title: Redesigned Zinc Finger Proteins: Design Strategy and Its Application
Dr. Shigeru Negi, Assistant Professor, Doshisha Women's University, Japan

Session 1-5: Structure Biology, Protein Structure, Dynamics and Functions (Part I )

(Time: 08:30-12:10, March 24, 2011, Thursday; Place: Room No. 202A, 2F, CNCC) 

Chair:

Dr. Olga Gursky, Associate Professor, Department of Physiology and Biophysics, Boston University School of Medicine, USA 

Co-Chair:

Dr. Alexei Vitalievich Finkelstein, Head of Laboratory, Institute of Protein Research, Russian Academy of Sciences, Russia

08:30-08:55

Title: Exploring the Universe of Protein Structures beyond the Protein Data Bank
Dr. Flavio Seno, Professor, University of Padua, Italy

08:55-09:20

Title: Lipoprotein Alchemistry: Structural Remodeling of Very Low-density Lipoprotein by Thermal Perturbation
Dr. Olga Gursky, Associate Professor, Department of Physiology and Biophysics, Boston University School of Medicine, USA

09:20-09:45

Title: Purification and Characterization of Phytoferritin from Legume Seeds
Dr. Guanghua Zhao, Professor of Food Biochemistry, College of Food Science & Nutritional Engineering, China Agricultural University, China

09:45-10:10

Title: <Golden Triangle>for Protein Folding Rates
Dr. Alexei Vitalievich Finkelstein, Head of Laboratory, Institute of Protein Research, Russian Academy of Sciences, Russia

10:10-10:30

Coffee break

10:30-10:55

Title: Structural Stability and Functional Activity of Non-specific Yersinia Porins
Dr. Olga D. Novikova, Head research officer, Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Russia

10:55-11:20

Title: Interaction of Actinoporins from Sea Anemones with Membrane Components
Dr. Margarita Monastyrnaya, Head research officer, Pacific institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Russia 

11:20-11:45

Title: Chimeric Kinesin-5 Motors Show Inhibition by Loop 5 Directed Compounds: Implications for Conservation of Allosteric Mechanisms
Dr. Edward J. Wojcik, Assistant Professor, Department of Biochemistry and Molecular Biology, LSU Medical School, USA

Session 1-5: Structure Biology, Protein Structure, Dynamics and Functions (Part II )

(Time: 08:30-11:20, March 25, 2011, Friday; Place: Room No. 205B, 2F, CNCC)

Chair:

Dr. Paul R. Gooley, Associate Professor, Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Australia

Co-Chair:

Dr. Rudolf K. Allemann, Professor, School of Chemistry, Cardiff University, UK 

08:30-08:55

Title: Mechanistic and Structural Studies of Sesquiterpene Synthases for an Expansion of the Terpenome
Dr. Rudolf K. Allemann, Professor, School of Chemistry, Cardiff University, UK

08:55-09:20

Title: Structural Insights on Isoform-specific Carbohydrate-binding Modules in the AMP-activated Protein Kinase
Dr. Paul R. Gooley, Associate Professor, Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Australia

09:20-09:45

Title: Dephosphorylation Regulation of RNa polymerase II in Eukaryotic Transcription
Dr. Yan Zhang, Assistant Professor, Department of Chemistry and Biochemistry, University of Texas, USA

09:45-10:10

Title: Quantitative study of molecular interactions in live cells by functionalFluorescence Microscopy Imaging (fFMI)
Dr. Vladana Vukojevic, Assistant Professor, Department of Clinical Neuroscience, Karolinska Institute, Sweden

10:10-10:30

Coffee break

10:30-10:55

Title: Effect of the Structure of Solvation Shell of Aromatic Amino Acids on their Interaction in Binary Solutions with Consequences on the Conformation and Transition Thermodynamics of Proteins
Dr. Sandor Kunsagi-Mate, Associate Professor, Head of the Department of General and Physical Chemistry, Faculty of Science, University of Pecs, Hungary

10:55-11:20

Title: Second Harmonic Generation of Peptides in Solution and in Interaction with Lipid Layers
Dr. Claire Loison, Researcher, CNRS and University of Lyon, France

Session 1-6: Membrane Proteins

(Time: 08:30-10:10, March 24, 2011, Thursday; Place: Room No. 202B, 2F, CNCC)

Chair:

Dr. Christopher M Koth, Scientist, Genentech, USA

08:30-08:50

Title: Structural Study on KCNE Family Proteins and Their Interaction with Voltage-gated Potassium Channels
Dr. CongBao Kang, Group Leader, Agency for Science, Technology and Research, Singapore  

08:50-09:10

Title: Human Protooncogene K-Ras4B: Membrane Association and Protein-protein Interactions
Dr. Vadim Gaponenko, Assistant Professor, Department of Biochemistry and Molecular Genetics, University of Illinois, USA

09:10-09:30

Title: Probing the Antidepressant Binding Sites on the Human Serotonin Transporter
Dr. Steffen Sinning, Assistant professor, Centre for Psychiatric Research, Aarhus Psychiatric University HospitalUniversity of Aarhus, Denmark

09:30-09:50

Title: The Membrane Expression of Cadherin 23 is Regulated by PDZ Domain- mediated Protein-protein Interactions
Dr. Zhigang Xu, Professor, School of Life Sciences, Shandong University, China

09:50-10:10

Title: Detergent Screening and Purification of Histidine Tagged Membrane Proteins-Novel Tools and Techniques
Dr. Ake Danielsson, Staff Scientist, GE Healthcare Bio-Sciences AB, Sweden 

Session 1-7: Proteins and Signaling

(Time: 08:30-10:35, March 24, 2011, Thursday; Place: Room No. 203A, 2F, CNCC)

Chair:

Dr. Wouter D. Hoff, Associate Professor, Department of Microbiology and Molecular Genetics, Oklahoma State University, USA

08:30-08:55

Title: Contrasting Genetic Architecture of Protein and Transcriptional Networks
Dr. Dragan Radulovic, Associate professor, Florida Atlantic University, USA

08:55-09:20

Title: Protein Robustness and Evolvability Probed by High-throughput Biophysics
Dr. Wouter D. Hoff, Associate Professor, Department of Microbiology and Molecular Genetics, Oklahoma State University, USA

09:20-09:45

Title: Mussel Adhesive Proteins: Characterization and Applications
Dr. Haeshin Lee, Assistant Professor, Department of Chemistry, The Gradute School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology, Korea

09:45-10:10

Title: Investigation on Interactions of Organometallic Ruthenium Inhibitors with Protein Tyrosine Phosphatase 1B by Mass Spectrometry
Dr. Fuyi Wang, Professor, The Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, China

10:10-10:35

Session 1-8: Protein Trafficking/ Transport/ Translocation, Assembly

(Time: 10:30-12:10, March 24, 2011, Thursday; Place: Room No. 202B, 2F, CNCC)

Chair:

Dr. Daniel Gillet, Professor, Institute of Biology and Technologies of Saclay, CEA, France 

Co-Chair:

Dr. Chuan Hu, Assistant Professor, Department of Biochemistry and Molecular Biology, University of Louisville School of Medicine, USA

10:30-10:55

Title: The Na+/H+ Exchanger Gene Family: Implications in Protein Trafficking and Human Disease
Dr. Masayuki Numata, Assistant Professor, Department of Biochemistry and Molecular Biology, University of British Columbia Canada

10:55-11:20

Title: Vesicle Trafficking of Integrins in the Migration and Metastasis of Cancer Cells
Dr. Chuan Hu, Assistant Professor, Department of Biochemistry and Molecular Biology, University of Louisville School of Medicine
USA

11:20-11:45

Title: Lysosomal Targeting of ABC Transporter TAPL (Transporter Associated with Antigen Processing Like)
Dr. Masatomo Maeda, Professor, Molecular Biology, School of Pharmacy, Iwate Medical University, Japan

11:45-12:10

Title: Mechanism of Action of the Translocation Domain of the Diphtheria Toxin
Dr. Daniel Gillet, Professor, Institute of Biology and Technologies of Saclay, CEA, France

Session 1-9: Protein Modifications and Metabolism

(Time: 13:30-14:45, March 24, 2011, Thursday; Place: Room No. 202A, 2F, CNCC)

Chair:

Dr. Jihua Wang, Professor, Biophysical Society of China, China

13:30-13:55

Title: Diabetes Caused Alternative Histone Modifications in Kidney and Liver of db/db Mice
Dr. Ling Zheng, Professor, Cell Biology, College of Life Sciences, Wuhan University, China  

13:55-14:20

Title: Proteomic Analysis of Ubiquitin-related Proteins in Plants
Dr. Yuki Yanagawa, Researcher, National Institute of Crop Science, National Agriculture and Food Organization, Japan

14:20-14:45

Title: Protein Modification with Reactive Aldehydes Causes Damage of Photosynthesis in Heat Stressed Plants
Dr. Yasuo Yamauchi, Assistant Professor, Laboratory of Functional Phytochemistry, Graduate School of Agricultural Science, Kobe University, Japan

Session 1-10: Intrinsically Disordered Porteins

(Time: 15:30-16:45, March 24, 2011, Thursday; Place: Room No. 202A, 2F, CNCC) 

Chair:

Dr.James Wing-Yiu Choy, Associate Professor, Department of Biochemistry, University of Western Ontario, Canada

15:30-15:55

Title: Structural Insights into Regulation of Activities of the Transcription Factor C/EBPbeta
Dr. Maria Miller, Macromolecular Crystallography Laboratory, USA

15:55-16:20

Title: Interaction of Intrinsically Disordered Prothymosin Alpha with Keap1 in Oxidative Stress Response
Dr. James Wing-Yiu Choy, Associate Professor, Department of Biochemistry, University of Western Ontario, Canada

16:20-16:45

Title: Study of Disease-associated Intrinsically Disordered Proteins by Molecular Dynamics Simulations
Dr. Jihua Wang, Professor, Biophysical Society of China, China

Session 1-11: The Hydrogen Bond and Hydrophobicity and Implications

(Time: 13:30-14:45, March 24, 2011, Thursday; Place: Room No. 202B, 2F, CNCC) 

Chair:

Dr. Janusz Lipkowski, Professor, Institute of Physical Chemistry, Poland

13:30-13:55

Title: Geometry, Thermodynamics, and Protein
Dr. Yi Fang, Mathematical Science Institute, Australian National University, Australia

13:55-14:20

Title: The Structural View on Hydrophobic Hydration
Dr. Janusz Lipkowski, Professor, Institute of Physical Chemistry, Poland

14:20-14:45

Session 2-1: Protein Screening, Bioassay and Discovery

(Time: 08:30-09:45, March 25, 2011, Friday; Place: Room No. 202B, 2F, CNCC)

Chair:

Dr. Dominic M. Desiderio, Professor, Department of Neurology, University of Tennessee Center for Health Science, USA

08:30-08:55

Title: Tumor Liberated Protein and Peptide Search for the Cell Gene and its Whole Sequence
Dr. Giulio Tarro, Professor, College of Medicine, University of Naples, Italy

08:55-09:20

Title: The Nitroproteome of the Human Pituitary
Dr. Dominic M. Desiderio, Professor, Department of Neurology, University of Tennessee Center for Health Science, USA

09:20-09:45

Title: Isolation, Purification and New Functions of Extracellular Matrix Proteins (ECMPs) from the Calcified Endoskeleton of Octocorallians
Dr. Azizur Rahman, Humboldt Research Fellow, Department of Earth and Environmental Sciences, Palaeontology & Geobiology, Ludwig-Maximilians-University Munich (LMU), Germany

Session 2-2: Protein Chips, Arrays and Protein Structures in Silico

(Time: 10:30-12:10, March 25, 2011, Friday; Place: Room No. 202B, 2F, CNCC)

Chair:

Dr. Fang Lai, Research Manager, Corning Inc., USA

Co-Chair:

Dr. Mats Inganas, Director, Applications & Technology Assessment, Gyros AB, Sweden

10:30-10:55

Title: Miniaturization of Analytical and Preparative Processes in a CD Format
Dr. Mats Inganas, Director, Applications & Technology Assessment, Gyros AB, Sweden

10:55-11:20

Title: Development of Multiplexed Assays with GPCR Microarrays
Dr. Fang Lai, Research Manager, Corning Inc., USA

11:20-11:45

Title: Computational Structure Models of Diferric and Apo Transferrin-Transferrin Receptor 1 and Transferrin Receptor 2 Complexes
Dr.Takaki Yamamura, Professor, Faculty of Nutritional Sciences, The University of Morioka, Japan

11:45-12:10

Title: Development of Micro-Well Based Protein Arrays to Study Cytokine, Chemokine and Protein-Protein Interactions and Bioactivityin Tears during the Diurnal Cycle and in Ocular Surface Tissue Diseases
Dr. Robert Sack, Professor, SUNY College of Optometry, USA

Session 2-3: NMR, EM and X-Ray Crystallography

(Time: 15:50-17:10, March 25, 2011, Friday; Place: Room No. 205B, 2F, CNCC)

Chair:

Dr. Guang Zhu, Professor, The Hong Kong University of Science & Technology, China

15:50-16:20

Title: Molecular Insights into Outer Membrane Protein Biogenesis
Dr. Marcelo C. Sousa, Associate Professor, Department of Chemistry and Biochemistry, University of Colorado, USA

16:20-16:45

Title: Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6
Dr. Guang Zhu, Associate Professor, The Hong Kong University of Science & Technology, China

16:45-17:10

Title: Biological Implications of Trimer Self-assembly in Solution and Crystal Structures of Mtb UreA
Dr. Li-Wei Hung, Team Leader, Los Alamos National Laboratory, USA

Session 3-1: Protein Networks in Disease

(Time: 13:30-16:45, March 23, 2011, Wednesday; Place: Room No. 203A, 2F, CNCC) 

Chair:

Dr. Chengtao Her, Associate Professor, School of Molecular Biosciences, Washington State University, USA

Co-Chair:

Dr. Zhong Chen, Staff Scientist, National Institute on Deafness and Other Communication Disorders, USA

13:30-13:55

Title:The Role of Vasohibin Family in the Regulation of Angiogenesis
Dr. Yasufumi Sato, Professor, Department of Vascular Biolog, Institute of Development, Aging and Cancer, Tohoku University, Japan

13:55-14:20

Title: The Role of hMSH4-hMSH5 Heterocomplex in DNA Repair and Damage Response is Controlled by Promiscuous Protein Interactions
Dr. Chengtao Her, Associate Professor, School of Molecular Biosciences, Washington State University, USA

14:20-14:45

Title: Inflammatory Signaling Pathways in Surgery-Induced Cognitive Decline
Dr. Niccolo Terrando, Postdoctoral Fellow, University of California, San Francisco, USA

14:45-15:10

Title: SH2B1 is a Novel Actin-binding Protein that Regulates Cytoskeletal Reorganization and Cell Migration
Dr. Maria Diakonova, Assistant Professor, Department of Biological Sciences, University of Toledo, USA

15:10-15:30

Coffee Break

15:30-15:55

Title: The LG 4-5 Region of Laminin Mediates Diverse Activities Altering Muscle Cells Survival and Proliferation
Dr. YanWen Zhou, Assistant Professor, University of Texas San Antonio, USA 

15:55-16:20

Title: NF-kB Interacting Pathways and Networks in Head and Neck Cancer Differing in p53 Status
Dr. Zhong Chen, Staff Scientist, National Institute on Deafness and Other Communication Disorders, USA

16:20-16:45

Title: Alpha-1 Antitrypsin Deficiency: Role in Chronic Obstructive Pulmonary Disease
Dr. Bala Gopal Unni, Scientist, North-East Institute of Science & Technology (CSIR), India  

Session 3-2: Proteins in Apoptosis and Autophagy

(Time: 08:30-09:45, March 24, 2011, Thursday; Place: Room No. 205A, 2F, CNCC)

Chair:

Dr. Shazib Pervaiz, Professor, National University of Singapore, Singapore

08:30-08:55

Title: Specialized Ribosomes in Human Mitochondria and their Role in Apoptosis
Dr. Thomas W. O'Brien, Professor, Interdisciplinary Center for Biotechnology Research, University of Florida, USA

08:55-09:20

Title: The A- and B-type Nuclear Lamin Interaction under Apoptosis
Dr. Songbi Chen, Professor and Deputy Director, Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, China

09:20-09:45

Title: Api5 as a New Therapeutic Target for Cancer Therapy
Dr. Jean-Luc Poyet, Research Director, INSERM, France

Session 3-3: G-Proteins, Signal Transduction and Diseases

(Time: 13:30-14:45, March 24, 2011, Thursday; Place: Room No. 203A, 2F, CNCC)

Chair:

Dr. Harry W. Jarrett, Lutcher Brown Distinguished Professor of Biochemistry, Department of Chemistry, University of Texas San Antonio, USA

13:30-13:55

Title: Signal Transduction, Skin Cancer and Nanoparticle Sunscreens
Dr. Visalini Muthusamy, NHMRC Research Fellow, RMIT University, Australia

13:55-14:20

Title: Muscular Dystrophy: The p21 and Heterotrimeric G-protein Signaling
Dr. Harry W. Jarrett, Lutcher Brown Distinguished Professor of Biochemistry, Department of Chemistry, University of Texas San Antonio, USA

14:20-14:45

Title: Network-based Identification of Core Autophagic Pathways as Novel Targets for Cancer Therapy
Dr. Bo Liu, Lecturer, State Key Laboratory Biotherapy and Cancer Center, Sichuan University, China

Session 3-4: Protein Misfolding and Cancers

Chair:

Dr. Joost Schymkowitz, Professor, VIB Switch Laboratory, Vrije Universiteit Brussel, Belgium

15:30-15:55

Title: The Proprotein Convertases (PC) as New Potential Therapeutic Cancer Targets
Dr. A-Majid Khatib, Director, INSERM, France

15:55-16:20

Title: Aggregation of p53 as a Mechanism of Tumour Suppresor Inactivation and Oncogenic Gain-of-function 
Dr. Joost Schymkowitz, Professor, VIB Switch Laboratory, Vrije Universiteit Brussel, Belgium

Session 3-5: Heat Shock Proteins

(Time: 10:55-12:10, March 25, 2011, Friday; Place: Room No. 202A, 2F, CNCC)

Chair:

Dr. Wolfgang Voos, Professor, Institute for Biochemistry and Molecular Biology, University of Bonn, Germany 

10:55-11:20

Title: Folding and Stability Studies of 40 Kda Heat Shock Protein Hsp40s, A Major Class of Chaperones Involved in Protein Quality Control
Dr. Carlos Ramos, Professor, University of Campinas, Brazil

11:20-11:45

TitleHeat Shock Protein 25 Expression in Mouse Cerebellum: A Topological Relationship to Tyrosine Hydroxylase Ectopically Expressing Cerebellar Purkinje Cell Subsets in Rolling Mouse Nagoya
Dr. Kazuhiko Sawada, Professor, Department of Physical Therapy, Faculty of Medical and Health Sciences, Tsukuba International University, Japan

11:45-12:10

Title: The Radiation Effects of Far Infrared Ray (FIR) on Cancer were Controlled by Heat Shock Protein 70 (HSP70)
Dr. Kikuji Yamashita, Associate Professor, Institute of Health Sciences, The University of Tokushima Graduate School, Japan  

Session 3-6: Protein Misfolding and Neurodegenerative Diseases

(Time: 08:30-11:45, March 25, 2011, Friday; Place: Room No. 203A, 2F, CNCC)

Chair:

Dr. Yong Zhang, Associate Professor, Department of Chemistry, Chemical Biology, and Biomedical Engineering, Stevens Institute of Technology, USA

Co-Chair:

Dr. Martin Margittai, Assistant Professor, Department of Chemistry and Biochemistry, University of Denver, USA

08:30-08:55

Title: Insight from New Tricks that Track Mutant Huntingtin Aggregation in Cells
Dr. Danny Hatters, Department of Biochemistry and Molecular Bioloty, The University of Melbourne, Australia

Title: Fragment Based Screening of Difficult Targets by SPR Imaging of Chemical Microarrays
Dr. Thomas Neumann, Head, Graffinity Pharmaeuticals, Germany

09:20-09:45

Title: High Accuracy Structural Information for Protein Active Sites and Applications in Drug Design
Dr. Yong Zhang, Associate Professor, Department of Chemistry, Stevens Institute of Technology, USA

09:45-10:10

Title: Coassembly of Tau Isoforms into Mixed Aggregates
Dr. Martin Margittai, Assistant Professor, Department of Chemistry and Biochemistry, University of Denver, USA

10:10-10:30

Coffee Break

10:30-10:55

Title: Characterising the Determinants and the Structure of the Membrane Association of the Endogenous N1 and N2 Prion Protein Fragments
Dr. Steven Collins, Associate Professor, Department of Pathology, The University of Melbourne, Australia

10:55-11:20

Title: A Hypothetical Model of Prion Misfolding and Prion Disease
Dr. Xuemin Ye, Associate Director, Neuropharmacology Division Beijing Joinn Laboratories, China

Session 3-7: Protein Misfolding and Amyloid Disease

(Time: 13:30-15:30, March 25, 2011, Friday; Place: Room No. 205B, 2F, CNCC)

Chair:

Dr Frederic Rousseau, Professor, VIB SWITCH Laboratory, Free University of Brussels, Belgium

13:30-13:50

Title: Molecular Biophysics of Membrane-active Peptides: From Mono Molecular Interactions to Amyloidogenesis
Dr. Jascindra Ravi, Higher Research Scientist, Biotechnology, National Physical Laboratory, UK

13:50-14:10

Title: Evolutionary Mechanisms against Protein Aggregation: Implications for Human Disease
Dr. Frederic Rousseau, Professor, VIB SWITCH Laboratory, Free University of Brussels, Belgium

14:10-14:30

Title: Identification and be Novo Design of Yeast Prion Domains
Dr. Eric D. Ross, Assistant Professor, Department of Biochemistry and Molecular Biology, Colorado State University, USA

14:30-14:50

Title: Treating Amyloidosis in Stromal Corneal Dystrophies
Dr. Ching Yuan, Assistant Professor, Ophthalmology, University of Minnesota, USA

14:50-15:10

Title: Amyloid Aggregation of Amyloid -peptide in the Presence of Model Membrane
Dr. Kenji Sasahara, Research Scientist, Division of Structural Biology, Graduate School of Medicine, Kobe University, Japan

15:10-15:30

Title: The Small Heal Shock Protein A-crystallin Acts as a Tumor Suppressor in Pancreas
Dr. David W. Li, Associate Professorr, University of Nebraska Medical Center, USA 

Session 4-1: MS, Imaging MS and MALDI-TOF in Proteomics

(Time: 13:30-15:10, March 23, 2011, Wednesday; Place: Room No. 203B, 2F, CNCC) 

Chair:

Dr. Karin Noy, Research Scientist, Siemens Corporate Research, USA.

13:30-13:55

Title: Quantitation of Intact Peptide using High Resolution Mass Spectrometry C considerations to Improve Analytical Characteristics
Dr. J.C. Yves Le Blanc, Senior Research Scientist, Department of Applied Research, USA

13:55-14:20

Title: MassQuest-A Comprehensive Proteomic Pipeline for Biomarker Discovery in Mass Spectrometry
Dr. Karin Noy, Research Scientist, Siemens Corporate Research, USA

14:20-14:45

Title: Biological Tissue Analysis using MS images with Mass Microscope
Dr. Yuki Hashi, General Manager, Shimadzu Global COE for Analytical & Technical Development, Shimadzu Corporation, Japan

Session 4-2: Bioinformatics, Structural and Functional Proteomics

(Time: 15:30-17:10, March 23, 2011, Wednesday; Place: Room No. 203B, 2F, CNCC) 

Chair:

Dr. Concettina Guerra, Professor, Information Engineering, University of Padova, Italy

15:30-15:55

Title: A Step towards the Prediction of the Folding Nucleus of Proteins
Dr. Jacques Chomilier, Group Leader, Protein Structure Prediction, CNRS and Paris 6 University, France

15:55-16:20

Title: Structure and Network-based Methods for the Prediction of Protein Interactions
Dr. Concettina Guerra, Professor, Information Engineering, University of Padova, Italy

16:20-16:45

Title: Biased Approach for the be Novo Prediction of Peptide and Miniprotein Structure
Dr. Pierre Tuffery, Director, In Silico Therapeutic Compounds, INSERM French National Institute for Health, France

16:45-17:10

Title: On the Identity and Functionality of Milk Proteins: Are Milk Proteins Merely a Source of Nutrition?
Dr. Qiang Zhang, Senior Scientist, Global R&D, Discovery & Analytical Sciences, Mead Johnson Nutrition, USA

Session 4-3: Nanoproteomics, Chip and Array Technologies in Proteomics

(Time: 10:30-11:45, March 24, 2011, Thursday; Place: Room No. 205A, 2F, CNCC)

Chair:

Dr. Don W. Arnold, General Manager, Eksigent Technologies, USA

10:30-10:55

Keynote Speech:
Title: High Throughput Epitope Mapping of Antibody Libraries using a High Density Peptide Array Platform
Dr. Klaus-Peter Stengele, General Manager, NimbleGen Systems GmbH, Germany

10:55-11:20

Title: cHiPLC-nanoflex: An Easy-to-use, Flexible and Reproducible Chip-based Technology for NanoLC-based Proteomics Research
Dr. Don W. Arnold, General Manager, Eksigent Technologies, USA

11:20-11:45

Title: Disease Proteomics of Posttranslational Modifications of Proteins Revealed by Agarose 2-DE and Quantum Dot Technology
Dr. Masamichi Oh-Ishi, Associate Professor, Department of Physics, Kitasato University School of Science, Japan

Session 4-4: Proteomics and Disease

(Time: 15:30-17:10, March 24, 2011, Thursday; Place: Room No. 202B, 2F, CNCC) 

Chair:

Dr. Marc Reymond, Chairman and Head, Gen, GI and Thoracic Surgery, EvKB, Germany

Co-Chair:

Dr. Peter Schulz-Knappe, CSO, Protagen AG, Germany

15:30-15:55

Title: Using Functional Proteomics to Dissect the Role of the Proteasome in Cardiomyopathy
Dr. Aldrin V. Gomes, Assistant Professor/Head, Neurobiology, Physiology and Behavior, University of California, USA

15:55-16:20

Title: Prognostic Markers in Cancer: A Critical Appraisal
Dr. Marc Reymond, Chairman and Head, Gen, GI and Thoracic Surgery, EvKB, Germany

16:20-16:45

Title: Auto-antibody Signatures for Disease Diagnosis in Cancer and Autoimmune Diseases
Dr. Peter Schulz-Knappe, Chief Scientific Officer, Protagen AG, Germany

16:45-17:10

Title: Systems Biology Approaches for Signaling Network in the Cardiac Hypertrophy
Dr. Young Sook Yoo, Principle Research Scientist, Integrated Omics Center, Korea Institute of Science and Technology, South Korea

Session 5-1: Phosphorylation & G-Protein Mediated Signaling Networks

(Time: 13:30-16:20, March 23, 2011, Wednesday; Place: Room No. 205A, 2F, CNCC) 

Chair:

Dr. Brian A. Hemmings, Professor, Friedrich Miescher Institute for Biomedical Research, Switzerland

Co-chair:

Dr. Weizhen Zhang, Assistant Professor, University of Michigan, USA

13:30-13:55

Title: Phosphates in T Cell Migration
Dr. Lena Maria Elisabeth Svensson, Principal Investigator, Experimental Medical Science, Lund University, Sweden

13:55-14:20

Title: Akt/PKB-mediated Phosphorylation of Twist1 is Crucial for Breast Cancer Metastasis
Dr. Brian A. Hemmings, Professor, Friedrich Miescher Institute for Biomedical Research, Switzerland

14:20-14:45

14:45-15:10

Title: Gastric mTOR is the Novel Target for Treatment of Obesity
Dr. Weizhen Zhang, Assistant Professor, University of Michigan, USA

15:10-15:30

Coffee Break

15:30-15:55

Title: BDNF Enhances Bcl-xL Expression through Protein Kinase CK2-activated and NF-kB-mediated Pathway in Rat Hippocampus
Dr. Eminy H.Y. Lee, Professor, Institute of Biomedical Sciences, Academia Sinica, Taiwan

15:55-16:20

Title: Galectin-1 as a Modulator of EGFR/PI3K Signaling
Dr. Timothy Lautenschlaege, Clinical Instructor, Radiation Oncology, The Ohio State University, USA

Session 5-2: Protein Kinase and Cell Cycle Control

(Time: 08:30-10:10, March 24, 2011, Thursday; Place: Room No. 205B, 2F, CNCC)

Chair:

Dr. Xiang S. Ye, Director of Lilly Oncology Discovery Asia, Eli Lilly and Company, USA

08:30-08:50

Title: Identification of Novel Protein Kinases Required for Proper Segregation of Chromosomes during Meiosis
Dr. Juraj Gregan, Group Leader, Max F. Perutz Laboratories, University of Vienna, Austria

08:50-09:10

Title: Cell Cycle Regulation as a Platform for Novel Cancer Drug Discovery
Dr. Xiang S. Ye, Director, Lilly Oncology Discovery Asia, Eli Lilly and Company, USA

09:10-09:30

Title: The Oncogenic Activity of CK2 Kinase is Mediated by Inhibition of Tumor Suppressor Activity of Ikaros in Leukemia
Dr. Sinisa Dovat, Associate Professor and Chiar, Pediatric Hematology/Oncology and Pharmacology, Penn State University College of Medicine, USA

09:30-09:50

Title: Role of CK2 on the Cell Cycle Checkpoints in Fission Yeast
Dr. Hiroshi Murakami, Associate Professor, Biochemistry and Cell Biology, Nagoya City University, Japan

09:50-10:10

Title: Role of ATR-Chk1 Signalling in the Control of DNA Replication
Dr. Eva Petermann, Lecturer, School of Cancer Sciences, University of Birmingham, UK

Session 5-3: Receptor Tyrosine Kinases

(Time: 10:30-12:10, March 24, 2011, Thursday; Place: Room No. 205B, 2F, CNCC)

Chair:

Dr. Don Michael Wojchowski, Director, Cell Biology and Regenerative Medicine, USA

10:30-10:50

Title: Phosphorylation of the Crk Adaptor Protein at Tyrosine 251: Novel Role in Abl Tyrosine Kinase Transactivation
Dr. Raymond B. Birge, Professor, Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, USA

10:50-11:10

Title: New Mediators of EPOR/Jak2 Kinase Action as Discovered via Global Transcriptome Analyses, and Defined via Novel Knock-out Mouse Models
Dr. Don Michael Wojchowski, Director, COBRE Center of Excellence in Stem, Cell Biology and Regenerative Medicine, USA

11:10-11:30

Title: Alternative TrkAIII Splicing and Cancer
Dr. Andrew Reay Mackay, Professor, Laboratory of Experimental Pathology, University of L'Aquila, Italy

11:30-11:50

Title: Interactions between Brain-derived Neurotrophic Factor and Glucocorticoids
Dr. Tadahiro Numakawa, Section Chief, Department of Mental Disorder Research, National Center of Neurology and Psychiatry, Japan

11:50-12:10

Title: Structural Study of an Oncogenic Mutation in RON Kinase Suggests How a Constitutive Activation Could Occur and Lead to Cancer
Dr. Jing Wang, Senior Research Investigator, OSI Pharmaceuticals, Inc., USA

Session 5-4: The EGF Receptor and Associated Signaling

(Time: 13:30-14:45, March 24, 2011, Thursday; Place: Room No. 205A, 2F, CNCC)

Chair:

Dr. Tzipora Goldkorn, Professor, Department of Internal Medicine, UC- Davis School of Medicine, USA

Co-Chair:

Dr. Xi-Long Zheng, Associate Professor, University of Calgary, Canada

13:30-13:55

Title: Regulation of EGF-stimulated EGF Receptor Endocytosis during M Phase
Dr. Zhixiang Wang, Professor, Cell Biology, University of Alberta, Canada 

13:55-14:20

Title: The EGF Receptor and Associated Signaling: Life and Death Decisions
Dr. Tzipora Goldkorn, Professor, Department of Internal Medicine, UC- Davis School of Medicine, USA

14:20-14:45

Title: New Strategy in Head and Neck Cancer: Combination Therapy Targeting the PI3kinase/Akt and EGFR Signaling Pathways
Dr. Yuh Baba, Chief of Otolaryngology, Ohtawara Red Cross Hospital, Japan

Session 5-5: Bacterial Protein Kinases

(Time: 15:30-16:45, March 24, 2011, Thursday; Place: Room No. 205A, 2F, CNCC) 

Chair:

Dr. Kirsten Jung, Professor, Biology, Ludwig-Maximilians-Universitaet Muenchen, Germany

15:30-15:55

Keynote Speech:
Title: Targeted Secretion Inhibitors: A Novel Platform for Therapeutic Proteins Affecting Cell Secretion
Dr. Keith Alan Foster, Founder and Chief Technology Officer, Syntaxin Ltd, UK

15:55-16:20

Title: New Insights into the YehU/YehT Histidine Kinase/Response Regulator System of Escherichia Coli
Dr. Kirsten Jung, Professor, Biology, Ludwig-Maximilians-University Muenchen, Germany

16:20-16:45

Title: Analysis of Protein-protein Interactions in Ethylene Signalling: Autokinase Activity of the Receptor Histidine Kinase ETR1 Modulates Interaction with Key Elements of the Signalling Cascade
Dr. Georg Groth, Head/Professor, Heinrich-Heine-University, Germany

Session 5-6: Protein Kinase Inhibitors in Cancer

(Time: 08:30-10:10, March 25, 2011, Friday; Place: Room No. 206A, 2F, CNCC)

Chair:

Dr. Ariel Fernandez, Karl F. Hasselmann Chair in Engineering, Professor of Bioengineering Rice University, USA

08:30-08:55

Title: The Prognostic Impact of Altered Regulation of The Protein Kinase Inhibitor P27 in Breast Cancer
Dr. Dan Hershko, Director/ Assosiate Professor, Head of the Breast Health Institute at Rambam Medical Center, Israel

08:55-09:20

Title: Translational Ideas in Molecular Cancer Therapy: Re-engineering Kinase Inhibitors to Reduce their Side Effects
Dr. Ariel Fernandez, Professor, Rice University, USA

09:20-09:45

Title: ICA-1, A Novel PKC-i Inhibitor Induces Apoptosis in Neuroblastoma Cells
Dr. Mildred Acevedo-Duncan, Research Associate Professor, Department of Chemistry, University of South Florida, USA

09:45-10:10

Title: Development of Multi-kinase Inhibitors for Cancer Therapy
Dr. Ning Xi, Co-founder, HEC Pharma Co. & Calitor Sciences, Inc., USA

Session 5-7: Wnt / Hedgehog / Notch/ Hippo Signaling Pathways

(Time: 13:30-15:10, March 25, 2011, Friday; Place: Room No. 206A, 2F, CNCC)

Chair:

Dr. Yonghe Li, Associate Professor, The University of Alabama at Birmingham, USA

13:30-13:55

Title: Non-autonomous and Context-dependent Control of Apoptosis by Deregulated Hedgehog Signaling in Drosophila
Dr. Andreas Bergmann,Associate Professor, Department of Biochemistry & Molecular Biology, MD Anderson Cancer Center, USA

13:55-14:20

Title: Mesd and its C-terminal Region Peptide are Universal Inhibitors of Wnt Co-receptors LRP5 and LRP6 and Block Wnt/-catenin Signaling in Cancer Cells
Dr. Yonghe Li, Associate Professor, Pharmacology and Toxicology, The University of Alabama, USA

14:20-14:45

Title: Regulation of Wnt Signaling by LRP6 Phosphorylation
Dr. Gary Davidson, Group Leader, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Germany

14:45-15:10

Title: Characteristic Lipidation of Wnt Proteins
Dr. Shinji Takada, Professor, Okazaki Institute for Integrative Bioscience, National Institute for Basic Biology, Japan

Session 6-1: Transmembrane Peptides as Novel Therapeutics

(Time: 13:30-16:20, March 23, 2011, Wednesday; Place: Room No. 205B, 2F, CNCC) 

Chair:

Dr. Wei-Chiang Shen, Professor, Pharmacology and Pharmaceutical Sciences, University of Southern California, USA 

13:30-13:55

Keynote Speech:
Title: Cell-penetrating Peptides for Cytosolic or Nuclear Transport
Dr. Wei-Chiang Shen, Professor, Pharmacology and Pharmaceutical Sciences, University of Southern California, USA 

13:55-14:20

Title: Tumor Specific Targeting of Boron by Protein Therapy and Immunoliposome
Dr. Hideki Matsui, Professor and Chairman, Dean of Graduate School, Okayama University, Graduate School of Medicine & Dentistry, Japan

14:20-14:45

Title: Role of Hydrophobicity on Mechanism of Action of Anticancer Peptides
Dr. Yuxin Chen, Professor, Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, Jilin University, China

14:45-15:10

Title: Transmembrane Delivery of Peptides and Proteins with Combination of Iontophoresis and Microporation
Dr. Yun Bai, Assistant Professor, Pharmaceutical Science, Philadelphia College of Osteopathic Medicine, USA

15:10-15:30

Coffee Break

15:30-15:55

Title: Multiple RGMa Domains Interact with Neogenin to Control Axonal Growth
Dr. Philippe Monnier, Scientist, Genetics and Development Division, Toronto Western Research Institute, Canada

15:55-16:20

Title: Molecular-targeted Anticancer Hybrid Peptide
Mrs. Liying Yang, Department of Pharmacoepidemiology, Kyoto University, Japan

Session 6-2: Target Discovery and Drug Delivery System

(Time: 13:30-16:45, March 24, 2011, Thursday; Place: Room No. 205B, 2F, CNCC) 

Chair:

Dr. Jiaan Yang, VP of Drug Discovery Technology, Sundia MediTech Company, Ltd., China

13:30-13:55

Title: Pak Kinases in Signaling and Transformation
Dr. Jeffrey M. Field, Professor, Department of Pharmacology, University of Pennsylvania, USA

13:55-14:20

Title: Protein-based Virtual Screening for Drug Binding Targets
Dr. Jiaan Yang, Vice President of Drug Discovery Technology, Sundia MediTech Company, Ltd., China

14:20-14:45

Title: Ambrx EuCODE A Mammalian Cell Based Platform for the Incorporation of Unnatural Amino Acids into Proteins for Drug Discovery and Development
Dr. Feng Tian, Associate Director, EuCODE Technology, Ambrx, Inc., USA

14:45-15:10

Title: Control of Glucose Transporter Expression and Cell Growth in Human Tumor Cells
Dr. Takayuki Kitagawa, Professor, Cell Biology and Molecular Pathology, Iwate Medical University, School of Pharmacy, Japan

15:10-15:30

Coffee Break

15:30-15:55

Title: Sonicated Protein Containers for Controlled Drug Release
Dr. Yongsheng Han, Professor, EMMS Group, Institute of Process Engineering, China

15:55-16:20

Title: Functional Proteomics Screening for Novel Drug Targets
Dr. Canhua Huang, Professor, Oncoproteomics Group, The State Key Lab of Biotherapy, West China Hospital,Sichuan University, China

16:20-16:45

Title: Effect of Fish Peptides in Treatment of Pancreatic Cancers and Mechanisms Involved in Resistance against Chemotherapeutic Drugs
Dr. Carlo Gunnar Ossum, Section for Cellular and Developmental Biology, University of Copenhagen, Denmark

Session 6-3: Protein Therapeutics for Immunologic & Inflammatory Diseases

(Time: 13:30-15:10, March 24, 2011, Thursday; Place: Room No. 206A, 2F, CNCC)

Chair:

Dr. Rowen J.-Y. Chang, Professor and Director, Institute of Molecular Medicine, University of Texas Health Science Center at Houston, USA

13:30-13:55

Title: Heat Shock Proteins are Targets of Disease Suppressive Anti-inflammatory T Cells
Dr. W. Van Eden, Professor, Division of Immunology, Utrecht University, The Netherlands

13:55-14:20

Title: Novel Non-native Protein Isomers for Vaccine and Antibody Development
Dr. Rowen J.-Y. Chang, Professor and Director, Institute of Molecular Medicine, University of Texas Health Science Center at Houston, USA

14:20-14:45

Title: Apolipoprotein A-I as an Immune Stimulating Protein
Dr. Jong-Young Kwak, Professor and Director, Department of Biochemistry, Dong-A University, South Korea

14:45-15:10

Title: In Vitro Evolution of Allergy Vaccine Candidates with Reduced IgE-binding and T-cell Activation Capacity
Dr. Ola B Nilsson, Department of Medicine, Karolinska Institute, Sweden

Session 6-4: Protein/Peptide Drug Discovery and Design

(Time: 08:30-11:45, March 25, 2011, Friday; Place: Room No. 205A, 2F, CNCC)

Chair:

Dr. Vettai S. Ananthanarayanan, Emeritus Professor, Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

Co-chair:

Dr. Joel Desharnais, Principal Scientist, Department of Chemistry, Pfizer/CovX, USA

08:30-08:55

Keynote Speech:
Title: Multi-parameter Cell-based Analysis of GPCRs and Kinases
Dr. Matthew Hsu, R&D Director, Bioscience Division, Merck Millipore, USA

08:55-09:20

Title: Molecular Chaperones for Structural Proteins as Potential Drug Targets
Dr. Vettai S. Ananthanarayanan, Emeritus Professor, Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

09:20-9:45

Title: The Many Faces of the GPCR Mas: Independent Intracellular Pathways and Consequences for Screening of Compounds Modifying Mas Signalling
Dr. Thomas Walther, Professor, Excellence Cluster Cardio-Pulmonary System, University of Giessen, Germany

09:45-10:10

Title: CovX-bodies: A New Scaffold for Peptide Conjugates.
Dr. Joel Desharnais, Principal Scientist, Department of Chemistry, Pfizer/CovX, USA

10:10-10:30

Coffee Break

10:30-10:55

Title: In Silico Screening for Small Molecules Interfering with Protein-protein Interactions
Dr. Stefan Guenther, Professor, Institute for Pharmaceutical Sciences, Albert-ludwigs-university Freiburg, Germany

10:55-11:20

Title: Structure based Design of Potent Soluble Epoxide Hydrolase Inhibitors with Improved hERG Profile
Dr. Qiaolin Deng, Research Fellow, Chemistry Modeling and Informatics, Merck Research Laboratories, USA

11:20-11:45

Title: Artibody: Polypeptide Affinity Reagents by Rational Design
Dr. Mikhail Soloviev, Senior Lecturer, School of Biological Sciences, University of London, UK

Symposium 7: Protein Expression

(Time: 13:30-16:45, March 25, 2011, Friday; Place: Room No. 205A, 2F, CNCC)

Chair

Dr. Dave Waugh, Senior Investigator, National Cancer Institute at Frederick, USA

Co-Chair

Dr. Erwan Bezard, Professor & Research Director, INSERM, France

13:30-13:55

Title: Rapid, High-yield Expression of Antibody Fragments and Non Natural Amino Acid Incorporation Using Cell-Free Synthesis
Dr. Gang Yin, Associate Director, Research Department, Sutro Biopharma, Inc., USA

13:55-14:20

Title: Endo- and Exoproteolytic Removal of Affinity Tags
Dr. Dave Waugh, Senior Investigator, National Cancer Institute at Frederick, USA

14:20-14:45

Title: Cell-free Expression of Membrane Proteins: Protocol Development and Quality Optimization for the High Level Production of Pharmaceutical Targets
Dr. Frank Bernhard, Lab Leader, Institute of Biophysical Vhemistry, Goethe-University of Frankfurt, Germany

14:45-15:10

Title: Targeted Modification of Yeast Membranes Dramatically Enhances GPCR Expression, Solubilization and Homogeneity
Dr. Renaud Wagner, Principal investigator, Receptors and Membrane Proteins, School of Biotechnology of Strasbourg, France

15:10-15:30

Coffee Break

15:30-15:55

Title: Gene Delivery in Neurodegenerative Diseases: From Model to Treatment Validation
Dr. Erwan Bezard, Professor & Research Director, INSERM, France

15:55-16:20

Title: Use of Yeast Surface Display Methodology for Preparation of High-affinity Recombinant Cytokines and their Antagonists-leptin Antagonists Story
Dr. Arieh Gertler, Professor, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University of Jerusalem, Israel

16:20-16:45

Title: Fast Production of Human Genome-wide Full-length Proteins through Transient Gene Expression
Dr. Guangli Wang, Director, Protein Production, OriGene Technologies, Inc., USA

Session 8-1: Protein Biomarker Discovery and Validation for Diagnosis and Treatment 

(Time: 13:30-14:45, March 23, 2011, Wednesday; Place: Room No. 206B, 2F, CNCC)

Chair

Dr. Xueji Zhang, Senior Vice President of Science, World Precision Instruments, Inc., USA

13:30-13:55

Title: An Early Marker, Kidney Injury Molecule 1 (KIM-1) in Human Urine: pH Sensitivity and Results from a Cadmium Polluted Region
Dr. Emmy Van Kerkhove, Professor of Physiology, Faculty of Medicine, Hasselt University, Belgium

13:55-14:20

Title: Hand-Held Cancer Biomarker Monitor- Yesterday, Today and Tomorrow
Dr. Xueji Zhang, Senior Vice President of Science, World Precision Instruments, Inc., USA

14:20-14:45

Title: Genetic Variation in Human Telomerase is Associated with Telomere Length in Ashkenazi Centenarians
Dr. Gil Atzmon, Director, Albert Einstein College of Medicine, USA

Session 8-2: Protein Biomarkers for Cancers

(Time: 08:30-10:10, March 24, 2011, Thursday; Place: Room No. 206A, 2F, CNCC)  

Chair

Dr. Herbert Thiele, Director Bioinformatics, Bruker Daltonik GmbH, Germany

08:30-08:55

Title: Sex Specific Transcriptomic Response to Environmental Exposure in Flemish Adults
Dr. Nicolas van Larebeke, Professor, Study Centre for Carcinogenesis and Primary Prevention of Cancer, Ghent University, Belgium

08:55-09:20

Keynote Speech:
Title: The Hybrid Technique of MR Imaging and MALDI-TOF Imaging as a new Milestone to Improve the Correlation of Anatomical Features and Molecular Information in Early Cancer Detection
Dr. Herbert Thiele, Director, Bioinformatics, Bruker Daltonik GmbH, Germany

09:20-09:45

Title: Effects of PTEN Status on Poly (ADP-ribose) Polymerase Inhibition in Addition to Radiation and Temozolomide in Glioblastoma
Dr. Erica Hlavin Bell, Research Assistant Professor, Department of Radiation Oncology, Comprehensive Cancer Center, The Ohio State University, USA

09:45-10:10

Title: Modelling of the Biologically Active Peptides from the Amino Acid Sequence of Human Alpha Fetoprotein with Demonstration of Their Functional Activity
Dr. Elena Dudich, Head of department of Molecular & Cell biology, Institute of Immunological Engineering, Russia

Session 8-3: Protein Biomarkers for Diseases: Cardiovascular, CNS, Inflammation and Immunology

(Time: 10:30-12:10, March 24, 2011, Thursday; Place: Room No. 206A, 2F, CNCC)

Chair

Dr. Marek Jankowski, Associate Professor, Dpartement de Mdicine, Universit de Montral, Centre de Recherche, Canada

10:30-10:55

Title: Proteomics and Immunomics in Neurological Diseases
Dr. Bruno Bonetti,Associate Professor in Neurology, University of Verona, Italy

10:55-11:20

Title: Cardiac Peptides in Diagnosis and Therapy of Heart Pathologies
Dr. Marek Jankowski, Associate Professor, Centre de Recherche, Dpartement de Mdicine, Universit de Montral, Canada

11:20-11:45

Title: Strategic Use of Immuno-enhanced Nano-LC-MS/MS for the Absolute Quantification of Protein Biomarkers in Support of CNS Programs
Dr. Yanhua (Jenny) Zhang, Senior Scientist, Pharmacokinetics, Dynamics, & Metabolism, Pfizer Global Research & Development, USA

11:45-12:10

Title: Recent Perspectives of C-Reactive Protein throughout the Spectrum of Cardiovascular Disease
Dr. Syed Shahid Habib, Associate Professor & Consultant, Department of Physiology, College of Medicine, King Saud University, Saudi Arabia

Session 9-1: Protein Biomaterial Design and Applications

(Time: 10:30-12:10, March 25, 2011, Friday; Place: Room No. 206A, 2F, CNCC)

Chair

Dr. Norbert Hampp, Professor, Philipps-University of Marburg,  Applied Biophysical Chemistry, Germany

10:30-10:55

Title: Crystal Structure of Bacterial RNA Polymerase Bound with a Transcription Inhibitor Protein, Gfh1
Dr. Thirumananseri Kumarevel, Senior Research Scientist, Biometal Science Laboratory & Advanced Protein Crystallography Group, Japan

10:55-11:20

Title: Shape, Dynamics and Crystallinity of Purple Membranes Comprising Bacteriorhodopsin Wildtype and the Variant D85T
Dr. Norbert Hampp, Professor, Applied Biophysical Chemistry, Philipps-University of Marburg, Germany

11:20-11:45

Title: Application of Supramolecular Protein Ferritin in Nanotechnology
Dr. Bin Zheng, Assistant Professor, Nara Institute of Science and Technology, Japan

11:45-12:10

Title: Design of Artificial Enzymes as New Biocatalysts
Dr. Jose M. Palomo, Tenure Scientist, Institute of Catalysis (CSIC), Spain

Session 9-2: Peptide-Polymer Nanofibers and Applications

(Time: 13:30-16:20, March 25, 2011, Friday; Place: Room No. 208A, 2F, CNCC) 

Chair:

Dr. Gregory A. Sotzing, Professor of Chemistry and Polymer Science, Polymer Program Director, Department of Chemistry and Institute of Materials Science, University of Connecticut, USA 

Co-Chair:

Dr. Max Ryadnov, TAR Leader/Principal Research Scientist, Bioengineering and Biotechnology, National Physical Laboratory, UK

13:30-13:55

Keynote Speech:
Title: Designing Peptide based Nanomaterials
Dr. Rein V. Ulijn, Professor, University of Strathclyde, UK

13:55-14:20

Title: FRET based DNA Nanofibers for White Lighting and the Importance of DNA Sequence on Efficiency
Dr. Gregory A. Sotzing, Professor of Chemistry and Polymer Science, Polymer Program Director, Department of Chemistry and Institute of Materials Science, University of Connecticut, USA

14:20-14:45

Title: De Novo Modulation of Native Folding Phenomena: From Protein Self-Assembly to Biological Recognition
Dr. Max Ryadnov, TAR Leader/Principal Research Scientist, Bioengineering and Biotechnology, National Physical Laboratory, UK

14:45-15:10

Title: Precise Control of Release Rate for Protein Therapeutic Agents
Dr. Sam Zhang, Professor, School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore

15:10-15:30

Coffee Break

15:30-15:55

Title: Fabrication of Elastin and Related Polypeptide Nanoparticles by Gamma-irradiation
Dr. Masakazu Furuta, Associate Professor, Osaka Prefecture Radiation Research Institete, Osaka Prefecture University, Japan

15:55-16:20

Title: Engineering of Peptide Amphiphile Nanofibers for Regenerative Medicine
Dr. Hossein Hosseinkhani, Professor, Department of Biomedical Engineering, National Yang Ming University, Taiwan

Session 10-1: Chip and Microarray Technology for Protein Analysis

(Time: 13:30-16:20, March 23, 2011, Wednesday; Place: Room No. 206A, 2F, CNCC) 

Chair

Dr. Zhichao Pei,Distinguished Professor, College of Science, Northwest A&F University, China

13:30-13:55

Title: Proteomic Analysis of Soybean Roots under Aluminum Stress
Dr. Khairy Soliman, Professor, Natural Resources & Environmental Science, Alabama A&M University, USA

13:55-14:20

Title: Quartz Crystal Biochips for Real-time Kinetic Analysis of Carbohydrate-protein and Protein-protein Interactions
Dr. Zhichao Pei, Distinguished Professor, College of Science, Northwest A&F University, China

14:20-14:45

Title: Affinity Arrays for Next Generation Plasma Profiling
Dr. Jochen M. Schwenk, Facility Manager, Biobank Profiling, SciLifeLab Stockholm, Sweden

14:45-15:10

Title: Chemical Strategies for Generating Protein Biochips
Dr. Pascal Jonkheijm, Assistant Professor, Molecular Nanofabrication, University of Twente, The Netherland

15:10-15:30

Coffee Break

15:30-15:55

Title: Real Time, Multiplex and Label-free Bio-interaction Analysis (by Surface Plasmon Resonance Imaging)
Dr. Sophie Bellon, Project Manager, BioInteractions Division, Horiba Scientfic-Genoptics, France

15:55-16:20

Title:Prospecting and Modeling New Proteins Induced by Aluminum Stress in Maize Root Tips by Using cDNA Array
Dr. Geraldo Magela de Almeida Cançado, Head Researcher, Plant Biotechnology Laboratory, Agricultural Research Agency of Minas Gerais State, Brazil

Session 10-2: Chromatography and Spectroscopy in Protein Analysis

(Time: 08:30-11:20, March 24, 2011, Thursday; Place: Room No. 206B, 2F, CNCC)

Chair

Dr. Peiqiang Yu, Strategic Research Chair and Professor, College of Agriculture and Bioresources, University of Saskatchewan, Canada

08:30-08: 55

Title: Proteomic Response to Iron Deficiency in Arabidopsis
Dr. Jie Li, Assistant Professor, The State Key Laboratory of Plant Cell and Chromosome Engineering, Chinese Academy of Sciences, China

08: 55-09:20

Title: Synchrotron-radiation based Infrared Microspectroscopic Analysis of Protein in Complex Plant System
Dr. Peiqiang Yu, Strategic Research Chair and Professor, College of Agriculture and Bioresources, University of Saskatchewan, Canada

09:20-09:45

Title: Taylor Dispersion Analysis; A Rapid, Nanolitre Method to Monitor Protein Aggregation Behaviour
Dr. Wendy Louise Hulse, Lecturer, Department of Biopharmaceutical, University of Bradford, UK

09:45-10:10

Title: Introduction of Implens Nanophotometer and Kurabos Nucleic Acid Extraction System
Dr. Xiaochun Shi,Life Science Products Specialist, Marketing, Techcomp (China) Ltd., China

10:10-10:30

Coffee Break

10:55-11:20

Title: Quality Assurance in Protein Analysis: A Multiparametric Challenge
Dr. Heinz Schimmel, Scientific Officer, European Commission-Joint Research Centre, Belgium

Session 11-1: Cell Culture and Upstream Process Development

(Time: 08:30-10:50, March 25, 2011, Friday; Place: Room No. 206B, 2F, CNCC)

Chair

Dr. Tiffany D. Rau, Global Technology Manager, Pall Corporation Life Sciences, USA

Co- Chair

Dr. David (Xiaojian) Zhao, Director of Research and Development, EMD Chemicals Inc., USA

08:30-08:50

Title: A Hypothesis Driven Medium Development Process with an Emphasis on Individual Component Optimization
Dr. Soverin Karmiol, Manager, Cell Sciences and Development, Sigma-Aldrich, USA

08:50-09:10

Title: An Upstream Technology and a Philosophy Devoted to Manufacturability of Biopharmaceuticals
Dr. Aziz Cayli, CEO,Cellca GmbH, Germany

09:10-09:30

Title: From Discovery to Commercialization: Delivering the Biopharmaceutical Pipeline using High-throughput Bioreactors
Dr. Tiffany D. Rau, Global Technology Manager, Pall Corporation Life Sciences, USA

09:30-09:50

Title: Cell Culture Development with Science, Speed and Quality
Dr. David (Xiaojian) Zhao, Director of Research and Development, EMD Chemicals Inc., USA

09:50-10:10

Coffee Break

10:10-10:30

Title:Cell Culture Process Development for Biosimilar Version Monoclonal Antibodies
Dr. SooYoungLee, Senior Manager, R&D Division, Celltrion Inc., South Korea

10:30-10:50

Title: Cost-effective Platform for Production of Functional Recombinant Pharmaceuticals Proteins through Transgenic Rice Seeds
Dr. Daichang Yang, Professor, College of Life Sciences, Wuhan University, China

Session 11-2: Scaling Up Bioprocess Development for Biotherapeutics

(Time: 15:30-16:45, March 25, 2011, Friday; Place: Room No. 206A, 2F, CNCC)

Chair

Dr. Rolf G. Werner, Vice President, Department of Biopharmaceuticals, Boehringer Ingelheim GmbH, Germany

15:30-15:55

Title: Technology Leadership in Biopharmaceutical Manufacturing
Dr. Rolf G. Werner, Vice President, Department of Biopharmaceuticals, Boehringer Ingelheim GmbH, Germany

15:55-16:20

Title: Current Advances in Large-scale mAb Purification
Dr. Hans J Johansson, Staff Scientist, Research and Development, GE Healthcare Bio-Sciences, Sweden

Title: Considerations on the Scale-up of Ultrafiltration/Diafiltration Step for Antibody Purification Processes

Session 11-3: Improved Separation, Purification, Recovery, Crystallization, and Lyophilization

(Time: 13:30-17:10, March 25, 2011, Friday; Place: Room No. 202A, 2F, CNCC) 

Chair:

Dr. Peter R. Levison, Technology Development Director, Biopharmaceutical R&D, Pall Life Sciences, UK

Co-Chair:

Dr. Robert T. Forbes, Professor, Bradford School of Pharmacy, University of Bradford, UK

13:30-13:55

Title: Fluorescence-based Size Exclusion Chromatography: A Novel Method to Bridge the Gap from DNA Clone to Protein Structure
Dr. Christopher M. Koth, Scientist, Structural Biology, Genentech, USA

13:55-14:20

Title: Approaches to Improve Selectivity of Large-scale Chromatographic Processes
Dr. Peter R. Levison, Technology Development Director, Biopharmaceutical R&D, Pall Life Sciences, UK

14:20-14:45

Title: Nanoscale Screening to De-risk Separation and Isolation Bottle-necks
Dr. Robert T. Forbes, Professor, Bradford School of Pharmacy, University of Bradford, UK

14:45-15:10

Title: Platform Technology for Developing Purification Processes
Dr. Michel Eppink, Head, Department of Downstream Processing, Synthon BV, The Netherlands

15:10-15:30

Coffee Break

15:30-15:55

Title: Hydroperoxide Lyase from Amaranthus Tricolor (Amaranthus Mangostanus L.) Leaves: Stabilization, Purification and Biogenesis of C6 Aldehydes
Dr. Yufei Hua, Professor, School of Food Science and Technology, Jiangnan University, China

15:55-16:20

Title: Purification of the Target Protein for Bioactive Metabolites
Dr. Minoru Ueda, Professor, Department of Chemistry, Tohoku University, Japan

16:20-16:45

Title: Using Multiple-affinity Tags to Produce High Levels of Soluble and in Vivo Biotinylated Proteins in Bacteria
Dr. Syed Salman Ashraf, Associate Professor, Department of Chemistry, UAE University, UAE

16:45-17:10

Title: Heterofunctional Supports for the One-Step Purification, Immobilization and Stabilization of large Multimeric Enzymes: Amino-glyoxyl Versus Amino-Epoxy Supports
Dr. Benevides Pessela, Turned Scientist, Department of Biotechnology and Microbiology, Institute of Food Technology, CIAL-CSIC, Spain

Session 12-1: Peptide Assembly and Biological Roles

(Time: 15:30-16:45, March 23, 2011, Wednesday; Place: Room No. 206B, 2F, CNCC) 

Chair

Dr.Il Kim, Professor and Director, Polymer Science and Eng, Pusan National University, South Korea

15:30-15:55

Title: Fragmentomics: The Brilliant World of Protein and Peptide Fragments.
Dr. Alexander A. Zamyatrnin, Professor and Scientist General, Computer Biochemistry Group, Russian Academy of Sciences, Russia

15:55-16:20

Title: Self-assembly and Applications of Synthetic Polymer Polypeptide Conjugate Hybrid Materials
Dr.Il Kim, Professor and Director, Polymer Science and Eng, Pusan National University, South Korea

16:20-16:45

Title: Synthesis of the Glycosamino Glycan-protein Linkage Tetraosyl Peptide Moieties of Betaglycan, Which Serve as a Hexosamine Acceptor for Enzymatic Glycosyl Transfer
Dr. Jun-ichi TamuraProfessor, Regional Environment, Tottori University, Japan

Session 12-2: Peptide Synthesis

(Time: 08:30-10:35, March 24, 2011, Thursday; Place: Room No. 210B, 2F, CNCC)

Chair

Dr. Gregg B. Fields, Professor, Department of Biochemistry, University of Texas Health Science Center, USA

Co-Chair

Dr. Patrick Perlmutter, Professor, School of Chemistry, Monash University, Australia

08:30-08:55

Title: Tinkering with Natures Tissue Scaffolds: Study and Application of Collagen and Collagen Mimetic Peptide Hybridization
Dr. Michael Seungju Yu, Associate Professor, Department of Materials Science and Eng., Johns Hopkins University, USA

08:55-09:20

Title: Synthesis and Application of Collagen-model Triple-helical Peptides
Dr. Gregg B. Fields, Professor, Department of Biochemistry, University of Texas Health Science Center, USA

09:20-09:45

Title: Segment Condensation: A Complementary Strategy with Increasing Importance in Peptide Chemistry
Dr. Xin-jun Zhang, Director, Research & Development, SciLight Biotechnology, LLC, China

09:45-10:10

Title: New Strategies for the Self-assembly and Functionalization of Beta-peptides
Dr. Patrick Perlmutter, Professor, School of Chemistry, Monash University, Australia

10:10-10:35

Title: Conformational Landscape of Anion-recognition Peptide-motifs: A Computational and Spectroscopic Approach
Dr. Raja Banerjee, Associate Professor and Head, Department of Bioinformatics, West Bengal University of Technology, India

Session 12-3: Peptide-Peptide Interactions

(Time: 10:55-11:45, March 24, 2011, Thursday; Place: Room No. 210B, 2F, CNCC)

Chair

Dr. Gregg B. Fields, Professor, Department of Biochemistry, University of Texas Health Science Center, USA

10:55-11:20

Title: How NMR Diffusion and 13c Relaxation Measurements in Solution Can Provide Insight into the Pore Formation Mechanism of a Cyclic Lipodepsipeptide
Dr. Jos C. Martins, Professor, Organic Chemistry/NMRSTR, Ghent University, Belgium

11:20-11:45

Title: DFT Study of H-bonds in the Peptide Secondary Structures. Polar Side-chains Interactions and Salt Bridges
Dr. Mikhail V. Vener, Associate Professor, Quantum Chemistry, Mendeleev University of Chemical Technology, Russia

Session 12-4: Antimicrobial Peptides 

(Time: 15:30-17:10, March 24, 2011, Thursday; Place: Room No. 206A, 2F, CNCC) 

Chair

Dr. Jos C. Martins, Professor, Universiteit Gent, Belgium

Co- Chair

Dr. Yuxin Chen, Professor, Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, Jilin University, China

15:30-15:55

Title: New Antibacterial Peptides of the Lantibiotic Family
Dr. Vladimir P. Korobov, Head, Microorganisms Development Biochemistry Laboratory, Institute of Ecology and Genetics of Microorganisms, Russian Academy of Sciences, Russia

15:55-16:20

Title: Antimicrobial Peptides Combatting against Multi-drug Resistant and Biofilm Forming Bacterial Infections
Dr. Kyung-soo Hahm, Professor and Director, Institute of Medical Science, Chosun University, South Korea

16:20-16:45

Title: Leguminous Seed Extracts: Antibacterial Peptides Screening & Isolation
Dr. Rakrudee Sarnthima, Protein and Enzyme Technology Research Unit, Department of Chemistry, Mahasarakham University, Thailand

16:45-17:10

Title: Interactions between Model Cell Membranes and Indolicidin Analogues and their Implications to Peptide Design
Dr. Ching-Wei Tsai, Post-doctor, Chemical and Materials Engineering, National Central University, Taiwan

Session 12-5: Peptides Bioengineering

(Time: 13:30-16:45, March 24, 2011, Thursday; Place: Room No. 207, 2F, CNCC)

Chair

Dr. Chris Ullman, Chief Scientific Officer, Isogenica Ltd., UK

Co-Chair

Dr. Robin Polt,Professor, Chemistry & Biochemistry, University of Arizona, USA

13:30-13:55

Keynote Speech:
Title: The PEPperCHIP Platform: Next Generation Peptide Microarrays for Antibody Analysis, Serology, and Peptide Design
Dr. Volker Stadler, CEO, PEPperPRINT GmbH, Germany

13:55-14:20

Title: Peptide Discovery and Engineering Using Next Generation Approaches
Dr. Chris Ullman, Chief Scientific Officer, Isogenica Ltd., UK

14:20-14:45

Title: Drugs for the Brain from the Brain: Glycosylation of Neuropeptides
Dr. Robin Polt, Professor, Chemistry & Biochemistry, University of Arizona, USA

14:45-15:10

Title: Structure-activity Relationships of Alpha-conotoxins: Applications in Drug Design
Dr. David J. Craik, Professor, University of Queensland, Australia

15:10-15:30

Coffee Break

15:30-15:55

Title: Voltage-clamp Measurements on Lipid Bilayers at the Onset of Peptide Attacks before Pore Formation
Dr. Giulia Fadda, Associate Professor, Laboratoire Lon Brillouin, France

15:55-16:20

Title: Peptides with Multiple Bioactivities: The Rules of Functional Promiscuity 
Dr. Octvio Luiz Franco, Coordinator, Center of Proteomical Analyses and Biochemistry, Catholic University of Brasilia, Brazil 

Title: Best of Both Worlds----Rapidly Synthesize High Quality Peptides using the Microwave or Parallel Peptide Synthesizer
Dr. Liu Ye, Solution Team, Tegent Technologies Ltd., China

Workshop 1: Biotechnology and Technology Transfer

(Time: 10:50-12:10, March 25, 2011, Friday; Place: Room No. 206B, 2F, CNCC)

Chair:

Dr. Patrick Robert Carnegie, Emeritus Professor and CEO, Biotechnology International Advisory Services Pty. Ltd., Australia

Co-Chair:

Dr. Craig Richard Thomson, Director, Chemistry and Biotechnology, Murgitroyd & Company, UK

10:50-11:10

Title: How to Protect your Investment in Europe
Dr. Aylsa Williams and Zoe Clyde-Watson, Partners, Chemistry and Biotechnology Group, D Young & Co, UK

11:10-11:30

Title: Nurturing Young Entrepreneurial Scientists
Dr. Patrick Robert Carnegie, Emeritus Professor and CEO, Biotechnology International Advisory Services Pty. Ltd., Australia

11:30-11:50

Title: Raising Investment for a Protein and Peptide based Technology Venture based on Your Intellectual Property(IP)
Dr. Craig Richard Thomson, Director, Chemistry and Biotechnology, Murgitroyd & Company, UK

11:50-12:10

Title: The Gep Oncogene Interactions and Signaling Network in Cancer
Dr. Danny N. Dhanasekaran, Professor & Director, Stephenson Oklahoma Cancer Center, University of Oklahoma Health Sciences Center, USA

Young Scientists Forum 1

(Time: 13:30-16:45, March 25, 2011, Friday; Place: Room No. 202B, 2F, CNCC) 

Chair:

Dr. Samantha L. Gerlach, Post Doctoral Research Associate, Tulane University Health Sciences Center, School of Medicine, USA

Co-Chair:

Dr. Jiangning Song, NHMRC Peter Doherty Fellow, Biochemistry and Molecular Biology, Monash University, Australia

13:30-13:55

Title: Divergent Evolution of Protein Cores in Response to Divergent Functional Pressure
Dr. Haiming Huang, Postdoctoral Fellow, Donnelly Centre for Cellular & Biomolecular Research, University of Toronto, Canada

13:55-14:20

Title: Cyclotides Enhance the Antiviral Effects of HIV-1 Protease inHibitors
Dr. Samantha L. Gerlach, Post Doctoral Research Associate, Tulane University Health Sciences Center, School of Medicine, USA

14:20-14:45

Title: Predicting Substrates of Proteases Using Machine Learning Techniques and Sequence-derived Features
Dr. Jiangning Song, NHMRC Peter Doherty Fellow, Biochemistry and Molecular Biology, Monash University, Australia

14:45-15:10

Title: Hydrogen Bonds Activation Energy Temperature Dependence Studied by Inelastic Scattering on Amino Acids, Small Oligomers and Peptides
Dr. Francesco D'Amico, Collaborator and Post Doctor , Department of FERMI@elettra, Sincrotrone Trieste, Italy

15:10-15:30

Coffee Break

15:30-15:55

Title: Possible Involvement of Brain-derived Neurotrophic Factor (BDNF) Dysfunction in Synaptic Loss Caused by Phencyclidine
Dr. Naoki Adachi, Postdoctoral Fellow, Mental Disorder Research, National Center of Neurology and Psychiatry, Japan

15:55-16:20

Title:Peptide-loaded PH-sensitive Liposomes: Effective Penetration of Print 3G in the Nucleus of Cancer Cells
Dr. Emilie Ducat, Student, Department of Pharmacy, University of Liege, Belgium

16:20-16:45

Title: Discovery of Biomolecular Interactions by Literature Mining
Mr. Bjoern Andreas Gruening, Institute for Pharmaceutical Sciences, Albert-Ludwigs-University Freiburg , Germany

Young Scientists Forum II

(Time: 13:30-16:20, March 25, 2011, Friday; Place: Room No. 203B, 2F, CNCC) 

Chair

Dr. Keith D. Kikawa, Post-doctoral Fellow, Allie M. Lee Cancer Research Laboratory, University of Nevada, USA

Co-Chair

Dr. Nora Khaldi, Post-doctoral Researcher, School of Medicine & Medical Science, University College Dublin, Ireland

13:30-13:55

Title: Assessing Novel Regulators of EGFR-mediated Stat3 Activation in Cancer Using Bioluminescent Imaging
Dr. Rodney B. Luwor, Post-doctoral Fellow, Department of Surgery, Royal Melbourne Hospital and the University of Melbourne, Australia

13:55-14:20

Title: Alterations in Epidermal Growth Factor Receptor-related Signaling by Polyunsaturated Fatty Acids
Dr. Keith D. Kikawa, Post-doctoral Fellow, Department of Biochemistry, University of Nevada, USA

14:20-14:45

Title: Evolutionary Analysis of Charge, Disorder, pI and Oligopeptide Conservation in Milk Proteins: Implications for Peptide Design
Dr. Nora Khaldi, Post-doctoral Researcher, School of Medicine & Medical Science, University College Dublin, Ireland

14:45-15:10

Title: Pancreatic Cancer, Signal Transduction and Possible Effects of Fish Hydrolysates on Apoptosis and Proliferation
Ms. Anna Lindqvist Kaufmann, Study Scientist, Department of Biology, University of Copenhagen, Denmark

15:10-15:30

Coffee Break

15:30-15:55

Title: Biopharmaceuticals and Monoclonal Antibodies in Oncology Trialsa aross-sectional Analysis
Dr. Tobias Janowitz, Academic Clinical Fellow, Addenbrookes Hospital, University of Cambridge, UK

15:55-16:20

Title: Activation Suppression of NF-B Signaling Pathway for Tumor Apoptosis
Dr. Abhinav Grover, Doctoral Fellow, Biochemical Engineering and Biotechnology, Indian Institute of Technology, India