Beijing Continental Grand Hotel

 8:00-20:00

 Registration

 Session Chair:

Dr. Elizabeth N De Gaspari, Research Scientist of Immunology Departament of Adolfo Lutz Institute, Full Professor, University of Sao Paulo, Brazil

 Co-Chair:

Dr. Gertz I. Likhtenshtein, Professor of Chemistry and Chemical Biophysics, Department of Chemistry, Ben-Gurion University of the Negev, Israel

13:30-13:35

Welcome Introduction

13:35-14:00

Title: Generation of Therapeutic Antibodies against Inflammatory Disease and Cancer Targets with a Low Risk of Clinical Immunogenicity
Dr.Frank Carr, Director for Biologics Research, Babraham Research Campus, UK

14:00-14:25

Title: Unveiling the Mysteries of Postnatal Leydig Stem Cell Differentiation
Dr. Chamindrani Mendis-Handagama, Professor of Comparative Medicine, The University of Tennessee College of Veterinary Medicine, USA

14:25-14:50

Title: Evaluation of New Antigens and Adjuvants to Neisseria Meningitidis B and Implications for New Immunization Schedules
Dr. Elizabeth N De Gaspari, Research Scientist of Immunology Departament of Adolfo Lutz Institute, Full Professor, University of Sao Paulo, Brazil

14:50-15:15

Title: Stimmunology  and the SMARTube™ HIV&HCV - A Novel Technology for Stimulating Antibody Production in-vitro – Leading to the Detection of New, Early, and Unique Antibodies
Dr. Tamar Jehuda-Cohen, Adjunct Senior Lecturer, Technion, Israel Institute of Technology, Chief Technology Officer, SMART Biotech Ltd., Israel

15:15-15:30

Coffee Break

15:30-15:55

Title: Study of Local Dynamics of an Antibody Binding Cite and Developing Rapid, High Sensitive Quantitative Novel Fluorophotochrome Immunoassay (FPIA) in Solution Using Fluorophotochrome Phenomenon
Dr. Gertz I. Likhtenshtein, Professor of Chemistry and Chemical Biophysics, Department of Chemistry, Ben-Gurion University of the Negev, Israel

15:55-16:20

Title: Application of Antibodies to Analyzing Food Matrices: Ricin Detection as an Example
Dr. David L. Brandon, Research Chemist, USDA Agricultural Research Service, USA

16:20-16:45

Title: Helicobacter Pylori as a Vaccine Delivery System for Influenza Virus Antigens
Dr. Alma Fulurija, Head, Immunology, Helicobacter Lab, Ondek Pty Ltd, Microbiology and Immunology, University of Western Australia,  Australia

16:45-17:10

Title: Anomalous Immunogenic Properties of Serine Proteases
Dr. Hossein Yousofi Darani, Associated Professor, Shahrekord University of Medical sciences, Iran

17:10-17:30

Discussion

 Session Chair:

Dr. Stefan Dübel, Chair, Dept. of Biotechnology, Technische Universität Braunschweig, Germany

13:30-13:55

Title: Variable Lymphocyte Receptors as Natural Non-Ig Antigen-binding Proteins
Dr. Roy A. Mariuzza, Professor, Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, USA

13:55-14:20

Title: Towards Proteome Scale Antibody Selections Using Phage Display
Dr. Stefan Dübel, Chair, Dept. of Biotechnology, Technische Universität Braunschweig, Germany

 Session Chair:

 Dr. Galina Kaseko, Executive Director, Stephen Sanig Research Institute Limited, Australia

14:20-14:45

Title: Multiple Autocrine Loops - Improvement of Antibody Yields and Cell Growth in Human Hybridoma through Intelligent Engineering
Dr. Galina Kaseko, Executive Director, The Stephen Sanig Research Institute, Australia

14:45-15:10

Title: Cooperation of Dendritic Cells with Naïve Iymphocytes to Accomplish in vitro Stimulation of Immune Response
Dr. Pamela Holzlöhner, Research Fellow, Potsdam University, Germany

15:10-15:35

Title: Selection of Antibody Producing Cells by Toxine Conjugates
Dr. Katrin Messerschmidt, Research Fellow, Junior Research Group Antibody-Technologies,
Potsdam University, Germany

15:35-15:50

Coffee Break

Session Chair:

Dr. Maryam Tabrizian, Associate Professor, Department of Biomedical Engineering/Faculty of Dentistry, McGill University, Canada

Co-Chair:

Dr. Paul G. Charette, Associate Professor, Department of Electrical and Computer Engineering, University of Sherbrooke, Canada

08:30-08:50

Keynote Speech:
Title: Developing High Quality Monoclonal Antibodies for Native Epitope Recognition
Dr. Donghui Ma, Director of Immunology, OriGene Technologies Inc., USA

08:50-09:10

Title: Carbohydrate Chips for Study of Carbohydrate-lectin Interactions Using QCM Biosensors and Microarray Technologies
Dr. Zhichao Pei, Senior Scientist, Manager of Biochip R&D Department, Attana AB , Sweden

09:10-09:30

Title: High-throughput Proteomics Platforms for Biomarker Discovery and Quantification
Dr. Maryam Tabrizian, Associate Professor, Department of Biomedical Engineering/Faculty of Dentistry, McGill University, Canada

09:30-09:50

Title: On-chip Photonics Strategies for Miniaturized Diagnostic Devices
Dr. Paul G. Charette, Associate Professor, Department of Electrical and Computer Engineering, University of Sherbrooke, Canada

09:50-10:10

Title: Biomarker Discovery via Monoclonal Antibody Proteomics: Microarray Profiling with mAB Libraries Generated against the Natural Plasma Proteome
Dr. Laszlo Takacs, CSO and COO, Biosystems International SAS, France

10:10-10:30

Title: Microarray Gene Expression in Leishmania Donovani Clinical Isolates: Impacting Drug Development
Dr. Neeloo Singh, Assistant Director, Central Drug Research Institute, India

10:30-10:40

Coffee Break

10:40-11:00

Title: Novel Autoimmune Hepatitis-specific Autoantigens Identified Using Protein Microarray Technology
Dr. Lin Wu, Professor, Beijing Institute of Genomics, CAS, China

 Session Chair:

Dr. Anthony (Tony) Warford , Discipline Leader - Histopathology, Innovation Center China, AstraZeneca, China

Co-Chair:

Dr. Christoph Merten, Group Leader Microfluidics, ISIS University of Strasbourg/ European Molecular Biology Laboratory (EMBL) Heidelberg, France

08:30-08:35

Welcome Introduction

08:35-09:00

Title: Harnessing Somatic Hypermutation for Antibody Discovery & Optimization
Dr. David J. King, VP, Research, AnaptysBio Inc., USA

09:00-09:25

Title: High Throughput Immunohistochemical Antibody Screening
Dr. Anthony (Tony) Warford, Discipline Leader - Histopathology, Innovation Center China, AstraZeneca, China

09:25-09:50

Title: Fixation Tissue Microarrays as a Screening Platform for Untested Antibodies
Dr. William J Howat, Head of Histopathology/ISH, Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, UK

09:50-10:00

Coffee Break

10:00-10:25

Title: Human Combinatorial Antibody Library (HuCAL®) in Therapeutic Antibody Generation and High Throughput Screening
Dr.Kathrin Ladetzki-Baehs, Project Team Leader, MorphoSys AG, Germany

10:25-10:50

Title: Automated Panning and Screening of Antibodies from Phage Display Libraries
Antti Tullila, Research Scientist, VTT Technical Research Centre of Finland, Finland

10:50-11:15

Title: Construction of Synthetic Human scFv Phage Library on Lytic Phages and Screening for Specific Clones
Dr. Yuji Ito, Associate Professor, Kagoshima University, Japan

11:15-11:40

Title: Living Droplets: High-throughput Cell-based Assays on a Miniaturized Scale
Dr. Christoph Merten, Group Leader Microfluidics, ISIS University of Strasbourg/ European Molecular Biology Laboratory (EMBL) Heidelberg, France

11:40-12:00

Discussion

 Session Chair:

Dr. Zhongyu Zhu, Research Scientist, Basic Research Program, SAIC Frederick Inc, National Cancer Institute at Frederick, NIH, USA

 Co-Chair:

Dr.Jun Ouyang, Scientist , Protein Analytical Chemistry, Genentech Inc., USA

08:30-08:50

Title: PEGylation of Full-length Antibody and Antibody Fragments for Therapeutic Use
Dr. Pascal Bailon, Consultant, Bailon Consultants, USA

08:50-09:10

Title: Engineered Antibody Domains against Cancer and HIV
Dr. Zhongyu Zhu, Research Scientist, Basic Research Program, SAIC Frederick Inc, National Cancer Institute at Frederick, NIH, USA

09:10-09:30

Title: Enabling the Power of Peptides
Dr. Gary Woodnutt, Vice president of Biology, CovX, USA

09:30-09:50

Title: Antibody-drug Conjugates: Targeted Delivery of Potent Cancer Therapy
Dr.Jun Ouyang, Scientist , Protein Analytical Chemistry, Genentech Inc., USA

09:50-10:10

Title: A Fully Recombinant ELISA Based on in vivo Biotinylated Antibody Fragments is Effective for Routine Virus Detection
Dr. Lesley Torrance, Head of Plant Pathology Programme, Scottish Crop Research Institute, UK

10:10-10:20

Coffee Break

10:20-10:40

Title: Novel Nano-tweezers Peptides as Potential Biotherapeutics
Dr. Sangyong Jon, Associate Professor, Gwangju Institute of Science and Technology, Republic of Korea

10:40-11:00

Title: Disulfide-stabilized Single Chain Variable Fragment (Sc-dsFv) Libraries for Antibody Engineering
Dr. An-Suei Yang, Associate Research Fellow, Genomics Research Center, Academia Sinica, Taiwan

 Session Chair:

Dr. Juan Carlos Almagro, Research Fellow, Head, Antibody Design Group, Centocor R&D, Inc., USA

13:30-13:50

Title: Antibody Humanization: Two Case Studies
Dr. Juan Carlos Almagro, Research Fellow, Head, Antibody Design Group, Centocor R&D, Inc., USA

13:50-14:10

Title: Therapeutic Antibody Discovery and Development Using Humanized RabMAbs
Dr. Yongke Zhang, Director, Preclinical Development and Clinical Research, Epitomics Inc., USA

14:10-14:30

Title: Humanized Antibodies and Their Therapeutic Value
Dr. Turgut Imir, Professor, Department of Microbiology, Faculty of Medicine, Gazi University, Turkey

14:30-14:50

Title: Non-human Primate Immune Libraries Combined with Germline Humanization : A Recently Utilized, and Powerful Approach for the Isolation of Therapeutic Antibodies
Dr. Philippe Thullier, Group Leader, IRBA-CRSSA, La Tronche, France

 Session Chair:

Dr. Juan Carlos Almagro, Research Fellow, Head, Antibody Design Group, Centocor R&D, Inc., USA

14:50-15:10

Title: Novel Approach for Multi-trans Membrane Protein with the ”ADLib System”
Dr. Masa Fujiwara, President&CEO, Chiome Bioscience Inc., Japan

15:10-15:20

Coffee Break

 Session Chair:

Dr. Yun-Hwa Peggy Hsieh, Professor, Department of Nutrition, Food and Exercise Sciences, Florida State University, USA

Co-Chair:

Dr. Jun Liu, Senior Group Leader and Senior Scientist, Genentech, Inc., USA

15:20-15:40

Keynote speech:  
Title: Measuring Size Distributions of High Concentration Antibody Formulations - Identifying and Avoiding High Concentration Anomalies
Dr. Kevin Mattison, Senior Bioanalytical Scientist, Product Development, Malvern Instruments Inc., USA

15:40-16:00

Title: Molecular Characterization in Crude Samples and on Complex Targets such as Whole Cells, Using the Attana Quartz Crystal Microbalance Technology
Dr. Teodor Aastrup, CEO, Attana AB, Sweden

16:00-16:20

Title: Integrated Microfluidic Glycan Profiling on LabChip GXII
Dr. Raj Singh, Director, Biology R&D, Caliper Lifesciences, USA

16:20-16:40

Title: Monoclonal Antibodies Recognizing Species-specific and Thermal-stable Epitopes
Dr. Yun-Hwa Peggy Hsieh, Professor, Department of Nutrition, Food and Exercise Sciences, Florida State University, USA

16:40-17:00

Title: Use of Capillary Electrophoresis for Quantitative, Automated Analysis of Therapeutic Monoclonal Antibodies
Dr. Mark Lies, Strategic Marketing Manager, Beckman Coulter Inc., USA

17:00-17:20

Title: Understanding and Characterization of Misbehaving Antibodies
Dr. Jun Liu, Senior Group Leader and Senior Scientist, Genentech, Inc., USA

17:20-17:40

Title: BioAnalytical Platform Strategy for Protein Characterization at ImClone (Erbitux® as an Example)
Dr. Qinwei Zhou, Associate Vice President, BioAnalytical Science, ImClone Systems, A Wholly-owned Subsidiary of Eli Lilly and Company, USA

 Session Chair:

Dr. Robert J. Lee, Professor of Pharmaceutics, College of Pharmacy, (NCI) OSU Comprehensive Cancer Center (OSUCCC), (NSF) Nanoscale Science and Engineering Center (NSEC), USA

08:30-08:50

Title: Immunotargeted Nanovehicles for Drug and Oligonucleotide Delivery
Dr. Robert J. Lee, Professor of Pharmaceutics, College of Pharmacy, (NCI) OSU Comprehensive Cancer Center (OSUCCC), (NSF) Nanoscale Science and Engineering Center (NSEC), USA

08:50-09:10

Title: In vivo Imaging and Targeting of Inflammation: Nanoplatforms Targeting Intercellular Adhesion Molecule-1
Dr. Moonsoo M Jin, Assistant Professor, Department of Biomedical Engineering, Cornell University,USA

09:10-09:30

Title: Magnetic Nanoparticles Functionalized with Organic Ligands : Potential Use in the Diagnosis and Treatment of Advanced Solid Cancer
Dr. Daniele Barbaro, Professor, Diabetology Endocrinology Metabolic Disease, Department of Chemical Industrial , University of Pisa, Italy

09:30-09:50

Title: Antibody and Nanotechnology Used in Rapid Detection of Environmental Toxins
Dr. Feng-Yih Yu, Professor, Department of Biomedical Sciences, Chung Shan Medical University, Taiwan

09:50-10:10

Title: Delivery of Therapeutic Levels of Monoclonal Antibodies in vivo by Gene Transfer
Dr. Jianmin Fang, Professor, School of Life Science and Technology, Tongji University, China

10:10-10:30

Title: A Portable, Miniaturized Piezoresistive Microcantilever Label-free Sensor for C-reactive Protein Detection Based on Nanomechanics
Dr. Long-Sun Huang, Associate Professor, National Taiwan University, Taiwan

10:30-10:40

Coffee Break

 Session Chair:

Dr. Jean-Luc Jestin, Tenured Researcher, Département de Biologie Structurale et Chimie, Institut Pasteur, France

Co-Chair:

Dr. Oliver Zhang, Director, Antibody Drug Development, GenScript Corporation, China

08:30-08:35

Welcome Introduction

 08:35-09:00

Keynote Speech:
Title: FASEBA, a Powerful Tool to Engineer Expression Level, Stability and Affinity of Antibody Fragments
Dr. Oliver Zhang, Director, Antibody Drug Development, GenScript Corporation, China

09:00-09:20

Title: Phage-display Derived Single-chain Fragment Variable (scFv) Antibodies Recognizing Conformational Epitopes of Escherichia Coli Heat-labile Enterotoxin B-subunit
Dr. Roger James, Reader, Department of Infection, Immunity and Inflammation, University of Leicester, UK
Dr. Wen Yuang Chung, Department of Surgery, Royal College of Surgeons, Connolly Hospital, Ireland

09:20-09:40

Title: Phage Display-based Affinity Maturation of Antibody Fragments against Haptens to Generate Practical Diagnostic Reagents
Dr. Norihiro Kobayashi, Professor, Kobe Pharmaceutical University, Japan

09:40-10:00

Title: Construction and Application of a Compact Phage Display Human Antibody Library
Dr. Montarop Yamabhai, Associate Professor, School of Biotechnology, Suranaree University of Technology, Thailand

10:00-10:10

Coffee Break

10:10-10:30

Title: scFv and Fab Antibody Phage Display Libraries
Dr. Isaac J. Rondon, Associate Director, Genetic Engineering, XOMA (US) LLC, USA

10:30-10:50

Title: Selection and Affinity Maturation of Human Antibodies against Rabies Virus from a scFv Gene Library Using Ribosome Display
Dr. Xiaoling Zhao, Associate Professor, Institute of Health and Enviramental Medicine, China

10:50-11:10

Title: The Highly Stabilized Ribosome Display Technology for Selection of Functional Peptide Aptamers
Dr. Akira Wada, Research Scientist, Nano Medical Engineering Laboratory, Advanced Science Institute, RIKEN, Japan

11:10-11:30

Title: CIS Display: An in vitro Display Technology for the Selection of Therapeutic Proteins
Dr. Chris Ullman, CSO, Isogenica Ltd., UK

11:30-11:50

Title: Antibodies to Select Catalysts
Dr. Jean-Luc Jestin, Tenured researcher, Département de Biologie Structurale et Chimie, Institut Pasteur, France

11:50-12:10

Discussion

 Session Chair:

Dr. Hilde Revets, Senior Director of Technology, Ablynx NV, Belgium

10:40-11:00

Title: Nanobodies® as New Therapeutic Entities
Dr. Hilde Revets, Senior Director of Technology, Ablynx NV, Belgium

11:00-11:20

Title: Use of Intracellular Camelid Single Domain Antibodies (Nanobodies^®) as Immunomodulators of Cancer Cell Invasion
Dr. Jan Gettemans, Principal Investigator, Ghent University, Belgium

 Session Chair:

Dr. Makobetsa Khati, Research Group Leader, CSIR Biosciences, South Africa

13:30-13:50

Title: Immuno-aptamer TM: Improving the Sensitivity of Conventional Immuno-assays with Aptamer-related Technologies
Dr. Iwao Waga, Senior Researcher, Biotechnology, VALWAY Technology Center, NEC Soft, Ltd., Japan

13:50-14:10

Title: Aptamer Technology Complementing to Antibody
Dr. Jun Sheng Lin, Senior Scientist, Centre for Reproduction and Genomics, AgResearch, New Zealand

14:10-14:30

Title: Aptamers and Neurodegenerative Disorders
Dr. Ernst Heinen, Human Histology, Faculty of Medecine, Unversity of Liège, Belgium

14:30-14:50

Title: Aptamers: A New Technology Platform for Diagnostics, Therapeutics and Targeted Drug Delivery
Dr. Makobetsa Khati, Research Group Leader, CSIR Biosciences, South Africa

14:50-15:10

Title: Anticoagulant and Antithrombotic Effects Achieved with Single Stranded DNA
Dr. Jolán Hársfalvi, Associate Professor, Medical and Health Science Centre & Clinical Research Center, University Debrecen, Hungary

15:10-15:30

Title: A Study of Thrombin Aptamer Structure and Properties
Dr. Vera A Spiridonova, Senior Research Worker, Belozersky Institute of Physical-chemical Biology of  Lomonosov Moscow State University, Russia

15:30-15:50

Coffee Break

 Session Chair:

Dr. Adalberto Merighi, Professor, Department of Veterinary Morphophysiology, University of Torino, Italy

15:50-16:10

Title: Use of Gold-labeled Antibodies for Ultrastructural Localization of Neurotrophic Factors and Their Receptors in Somatosensory Pathways
Dr. Adalberto Merighi, Professor, Department of Veterinary Morphophysiology, University of Torino, Italy

16:10-16:30

Title: Targeting Selectins for the Imaging of Endothelial Activation in Inflammation
Dr. Dorian O Haskard, Head, Vascular Science Section, National Heart and Lung Institute, Imperial College, Hammersmith Hospital, UK

16:30-16:50

Title: Evaluating the Potential of ¹⁸⁸Re-SOCTA-Trastuzumab as a New Radioimmunoagent for Breast Cancer Treatment
Dr. Tsai-Yueh Luo, Associate Scientist, Institute of Nuclear Energy Research, Taiwan

16:50-17:10

Title: Fluid-dynamic Imaging Leading to Further Understanding of the Morphogenic Process Based on Stem Cells and Sustainable Process Including Immune Globulins
Dr. Ken Naitoh, Professor, Waseda Univerity, Japan

 Session Chair:

Dr.Jin-an Jiao, Executive Vice President of Product Development and Manufacturing, Hematech, Inc., USA

13:10-13:30

Title: An Innovative Platform Technology to Produce Human Antibodies in Genetically Engineered Bovine
Dr. Jin-an Jiao, Executive Vice President of Product Development and Manufacturing, Hematech, Inc., USA

13:30-13:50

Title: FcRn Overexpression Boosts Humoral Immune Response
Dr. Imre Kacskovics, Vice-Chair and CEO, ImmunoGenes AG, Hungary

13:50-14:10

Title: Generation of Conformation-specific Anti-prion Protein Monoclonal Antibodies by Using Prion Protein-Knockout Mice
Dr. Takashi Yokoyama, Team Leader, Prion Disease Research Team, Prion Disease Research Center, National Institute of Animal Health, Japan

14:10-14:30

Title: Generating Animal Models for the Central Nervous System Diseases by Immunotoxin Cell Targeting
Dr. Kazuto Kobayashi, Professor, Fukushima Medical Univesity, Japan

14:30-14:50

Title: Transgenic and Cloning Animals
Dr. Xiangyang Miao, Professor, Institute of Animal Science, Chinese Academy of Agricultural Science, China

14:50-15:10

Title: Plant Produced HIV-1 Antibody 2G12 for a Clinical Phase I Trial
Dr. Markus Sack, Institute for Molecular Biotechnology, RWTH Aachen University, Germany

15:10-15:30

Title: AbRice V1.0--A Pilot Program Towards Generate Antibodies against Each Rice Proteins
Dr. Guozhen Liu, Professor of Molecular Biology, VP, Beijing Protein Innovation Co., Ltd., China

15:30-15:40

Coffee Break

 Session Chair:

Dr. Davis Farmer, Chairman, MSM Protein Technologies, lnc., USA

13:30-13:55

Title: Thioredoxin/TBP-2 System in Immunoregulation and Anti-inflammatory Mechanism
Dr. Junji Yodoi, Professor, Department of Biological Responses, Insitute for Virus Research, Kyoto University, Japan

13:55-14:20

Title: Trastuzumab Inhibited Cell Proliferation by Suppressing Thioredoxin-1 in MCF Cells 
Dr. Jie Bai, Professor, College of Life Science and Technology, Kunming University of Science and Technology, China

 Session Chair:

Dr. Davis Farmer, Chairman, MSM Protein Technologies, lnc., USA

14:20-14:45

Keynote Speaker:
Title: Transmembrane and G-protein Coupled Receptor Targets
Dr. Davis Farmer, Chairman, MSM Protein Technologies, Inc., USA

14:45-15:10

Title: Recombinant Antibody-based Immunotherapeutics for Malignant Tumors
Dr. Chien-Tsun Kuan, Assistant Professor of Pathology, Director, Laboratory for Antibody Engineering & Antibody Therapeutics, Member, The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, USA

15:10-15:25

Coffee Break

 Session Chair:

Dr. Stuart Kellie, Associate Professor, School of Chemistry and Molecular Biosciences, Affiliate Principal Scientist, Institute for Molecular Bioscience, University of Queensland, Australia

08:30-08:50

Title: The Tyrosine Phosphatase PTPRJ in Macrophages and Mammary Cancer Epithelia
Dr. Stuart Kellie, Associate Professor, School of Chemistry and Molecular Biosciences, Affiliate Principal Scientist, Institute for Molecular Bioscience, University of Queensland, Australia

08:50-09:10

Title: CD148 Tyrosine Phosphatase as a Target for Antibody-based Anti-angiogenesis Therapy
Dr. Takamune Takahashi, Assistant Professor of Medicine and Cancer Biology, Vanderbilt University Medical Center, USA

 Session
Chair:

Dr. Tadashi Yamamoto, Professor, Institute of Medical Science, University of Tokyo, Japan

Co-Chair:

Dr. Helmout Modjtahedi, Senior Lecturer, Kingston University London, UK

09:10-09:30

Title: Advances and Challenges in the Use of Anti-EGFR Monoclonal Antibodies in Cancer
Dr. Helmout Modjtahedi, Senior Lecturer, Kingston University London, UK

09:30-09:50

Title: Development and Understanding of Anti-EGFR Antibody Erbitux in Cancer Therapy
Dr. Xiaoqiang Kang, Senior Group Leader, ImClone Systems Inc, a wholly-owned subsidiary of Eli Lilly and Company, USA

09:50-10:10

Title: Role of Repair Protein Rad51 in Regulating the Response to EGFR Tyrosine Kinase Inhibitors in Human Non-small Cell Lung Cancer Cells
Dr. Yun-Wei Lin, Associate Professor of Biochemical Science and Technology, National Chiayi University, Taiwan

10:10-10:30

Coffee Break

10:30-10:50

Title: Development of Fully Human Antibody Neutralizing VEGFR-2  
Dr. Jin-San Yoo, President and CEO, PharmAbcine, Inc, South Korea

10:50-11:10

 Title: Development of Novel ErbB2 Antibody and pH-responsive Immunoliposomes Targeting ErbB2/HER2 in Breast Cancer Cells
Dr. Kentaro Semba, Professor, Waseda University, Japan 

11:10-11:30

Title: Degradation of HER2 by Cbl-Based Chimeric Ubiquitin Ligases
Dr. Libo Yao, Professor, The Fourth Military Medical University, China

11:30-11:50

Title: Tyrosine Kinase Inhibitors
Dr. Henry Gomez, Director, Department of Medicine, Instituto Nacional de Enfermedades Neoplásicas, Perú

 Session Chair:

Dr. Songqing Na, Research Advisor, Oncology Research, Eli Lilly and Co., USA

13:30-13:55

Title: IRAK4 Kinase Activity is Required for Th17 Differentiation and Th17-mediated Disease
Dr. Songqing Na, Research Advisor, Oncology Research, Eli Lilly and Co., USA

13:55-14:20

Title: Possible Targets for Inhibition of JAK/STAT Signaling Using Specific Antibody
Dr. Hirohide Yoshikawa, Medical Doctor, Sassa General Hospital, Japan

14:20-14:45

Title: Targetting Chemokines in Treatment of Arthritis
Dr. Seema S. Ahuja, Professor of Medicine, South Texas Veterans Health Care Systems, University of Texas Health Science Center at San Antonio, USA

14:45-15:10

Title: Production and Characterization of Macrophage Migration Inhibitory Factor Neutralizing Single-chain Fv Antibody Fragment
Dr. Trai-Ming Yeh, Professor, Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Taiwan

15:10-15:25

Coffee Break

Session Chair:

Dr. David Naor, Professor of Immunology, Hebrew University Hadassah Medical School, Israel

Co-Chair:

Dr. Eytan R. Barnea, Clinical Associate Professor, The Society for the Investigation of Early Pregnancy, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, USA

15:25-15:50

Title: Targeting CD146 Antibody Inhibits Tumor Angiogenesis and Tumor Growth
Dr. Xiyun Yan, Vice Director, Institute of Biophysics, Chinese Academy of Sciences, China

15:50-16:15

Title: CD44 and RHAMM (CD168), Non-identical Twins, are Engaged in Support of Cell Migration, and Used as Therapeutic Targets in Cancer and Autoimmune Inflammation
Dr. David Naor, Professor of Immunology, Hebrew University Hadassah Medical School, Israel

16:15-16:40

Title: PreImplantation Factor (PIF*): Physiologic, Targeted Immune Modulation without Immune Suppression: Novel Biomarker / Safe Treatment in Pregnancy, Immunity and Transplantation
Dr. Eytan R. Barnea, Clinical Associate Professor, The Society for the Investigation of Early Pregnancy, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, USA

 Session Chair:

Dr. Pawel Kermer, Head Consultant, Vice Medical Director and PI, Department of Neurology, Center of Neurological Medicine, DFG Research Center for Molecular Physiology of the Brain (CMPB), University Hospital, Germany

11:20-11:40

Title: Amelioration of Huntingtin Toxicity by BAG1 through Modulation of Cellular Detoxification Mechanisms
Dr. Pawel Kermer, Head Consultant, Vice Medical Director and PI, Department of Neurology, Center of Neurological Medicine, DFG Research Center for Molecular Physiology of the Brain (CMPB), University Hospital, Germany

11:40-12:00

Title: Janus Kinases as Chaperones for Its Cytokine Receptors?
Dr. Sigrun Hofmann, Pediatrician, Staff Scientist, Technical University Dresden, Pediatric Research Laboratory, Childrens Hospital, Germany

 Session Chair:

Dr. Pawel Kermer, Head Consultant, Vice Medical Director and PI, Department of Neurology, Center of Neurological Medicine, DFG Research Center for Molecular Physiology of the Brain (CMPB), University Hospital, Germany

12:00-12:20

Title: Design of Aptamer-based Nanoparticle Carriers Targeting Prostate Tumors
Dr. Kaiming Ye, Associate Professor, Biomedical Engineering Program, College of Engineering, University of Arkansas, USA

Session Chair:

Dr. William (Bill) D. Phillips, Associate Professor, Physiology, University of Sydney, Australia

16:40-17:05

Title: Actions of Autoimmune Anti-MuSK IgG upon the Nicotinic Acetylcholine Receptor Scaffold at the Neuromuscular Junction
Dr. William (Bill) D. Phillips, Associate Professor, Physiology, University of Sydney, Australia

17:05-17:30

Title: Difference in Antibody Effect on Muscle Fiber Arophy and Muscle Pathology between AchR-Ab and MuSK Positive Myasthenia Gravis
Dr. Corrado Angelini, Professor, Department of Neurosciences, University of Padova, Italy

 Session Chair:

Dr. Teruo Inamoto, Assistant Professor, Department of Urology, Osaka Medical College, Japan

Co-Chair:

Dr. Jun Teishima, Assistant Professor, Department of Urology, Graduate School of Biomedical Sciences, Hiroshima University, Japan

15:40-16:00

Title: Novel Monoclonal Antibodies that Block Human Vascular Endothelial Growth Factor (VEGF) and Placental Growth Factor (PLGF) Function and Inhibit Tumor Angiogenesis and Tumor Growth in-vivo
Dr. Jim Zhou, President, Suzhou Stainwei Biotech, Inc, China

16:00-16:20

Title: Preclinical Studies of IMC-3G3, an Anti-platelet-derived Growth Factor Receptor Alpha Antibody with Antitumor Activity
Dr. Nick Loizos, Group Leader, ImClone Systems, a wholly owned subsidiary of Eli Lilly, USA

16:20-16:40

Title: Bevaciszumab (Avastin®) in the Treatment of Brain Tumors: A Review
Dr. William R. Shapiro, Chairman, Division of Neurology, Barrow Neurological Institute, USA

16:40-17:00

Title: E-cadherin Expression Potentiates Epidermal Growth Factor Receptors Targeted Therapy by Monoclonal Antibody
Dr. Teruo Inamoto, Assistant Professor, Department of Urology, Osaka Medical College, Japan

17:00-17:20

Title: The Emerging Role of Endoglin as a Target Antigen in Cancer
Dr. Carmelo Bernabeu, Research Professor, Centro de Investigaciones Biologicas, CSIC, Spain

17:20-17:40

Title: Abnormalities of FGF9 and FGFR2IIIb in Prostate Cancer
Dr. Jun Teishima, Assistant Professor, Department of Urology, Graduate School of Biomedical Sciences, Hiroshima University, Japan

 Session Chair:

Dr. Byoung S. Kwon, Distinguished Investigator, Director, R&D Center for Cancer Therapeutics, National Cancer Center, Korea

Co-Chair:

Dr. Daniel Afar, Sr. Director, Program Leader, Oncology Programs, Facet Biotech Corp., USA

15:25-15:55

Keynote Speaker:
Title: An Integrated Science-based Approach to Drug Development: Theurapeutic CD20 Antibodies Enter a New League
Dr. Paul W.H.I. Parren, Sr. Vice President, Research & Pre-Clinical Development, Genmab, The Netherlands

15:55-16:20

Title: Targeting CS1 with the Humanized Antibody Elotuzumab for the Treatment of Multiple Myeloma
Dr. Daniel Afar, Sr. Director, Program Leader, Oncology Programs, Facet Biotech Corp., USA

16:20-16:45

Title: Dendritic Cell Targeting and Induction of T Cell Responses against Cancer
Dr. Yvette van Kooyk, Professor, VU Universitiy Medical Centre, The Netherlands

16:45-17:10

Title: 4-1BB (CD137)-mediated Immunotherapy
Dr. Byoung S. Kwon, Distinguished Investigator, Director, R&D Center for Cancer Therapeutics, National Cancer Center, Korea

 Session Chair:

Dr. Christian Jackisch, Professor, Head, Department of Gynecology and Obstetrics and Breast Cancer Center, Klinikum Offenbach, Germany

 Co-Chair:

Dr. Kakil Ibrahim Rasul, Senior Consultant Physician in Haem/Oncology, Assisstant Professor of Clinical Medicine, Weill Cornell Medical College/ QatarHamad Medical Corporation, Al-Amal Hospital, Qatar

13:30-13:55

Title: Anti-HER2 Humanized Monoclonal Antibody, in Breast Cancer Treatment
Dr. Kakil Ibrahim Rasul, Senior Consultant Physician in Haem/Oncology, Assisstant Professor of Clinical Medicine, Weill Cornell Medical College/ QatarHamad Medical Corporation, Al-Amal Hospital, Qatar

13:55-14:20

Title: Antibodies Targeting the Her2-neu Receptor – From the Neoadjuvant Setting to Late Stage Disease
Dr. Christian Jackisch, Professor, Head, Department of Gynecology and Obstetrics and Breast Cancer Center, Klinikum Offenbach, Germany

14:20-14:45

Title: Trastuzumab Resistance: Etiology and Treatment
Dr. Evangelia Razis, Associate Director, 1st Dept. Medical Oncology, "HYGEIA" Hospital Greece

14:45-15:10

Title: Phospho-specific Antibody, a Very Important Tool in Cell Signaling Transduction Research
Dr. Mei Xu, Assistant of General Manager, Signalway Antibody Asian Center, China

15:10-15:30

Coffee Break

 Session Chair:

Dr. Masanori Noguchi, Professor of Clinical Research Division, Research Center for Innovative Cancer Therapy, Kurume University, Japan

15:30-15:55

Title: The Expression of EGFR in A549 Human Lung Cancer Cells and Human Lung Cancer Cells and the Effect of Verapamil
Dr. Chundi Zhang, Professor, Qiqihaer Medical University, China

 Session Chair:

Dr. Masanori Noguchi, Professor of Clinical Research Division, Research Center for Innovative Cancer Therapy, Kurume University, Japan

15:55-16:20

Title: Successful Control of Tumor Growth by a Combination of Adoptive Transfer of Tumor Reactive CD8+ T Cells and TGF-beta Antibody
Dr. Chung Lee, John T. Grahhack Professor, Northwestern University, Feinberg School of Medicine, USA

16:20-16:45

Title: PSMA-specific scFv for Prostate Cancer Imaging
Dr. Mariangela Figini, Antibody Engineering Group Leader, Fondazione IRCCS Istituto Nazionale Tumori Milano, Italy

16:45-17:10

Title: Immunotherapy for Patients with Hormone Refractory Prostate Cancer Using Suitable Peptides Selected by Peptide-specific Antibodies
Dr. Masanori Noguchi, Professor of Clinical Research Division, Research Center for Innovative Cancer Therapy, Kurume University, Japan

 Session Chair:

Dr. Barry J Allen, Professor and Director, Centre for Experimental Radiation Oncology, St George Cancer Care Centre, UNSW Clinical School, Australia

13:30-13:55

Title: Antiangiogenic Therapy for Patients with Advanced Melanoma
Dr. Michael B. Atkins, Professor of Medicine, Harvard Medical School, USA

13:55-14:20

Title: Patient Responses in a Phase 1 Clinical Trial of Targeted Alpha Therapy for Metastatic Melanoma
Dr. Barry J Allen, Professor and Director, Centre for Experimental Radiation Oncology, St George Cancer Care Centre, UNSW Clinical School, Australia

14:20-14:45

Title: Cutaneous and Mucosal (Primary and Secondary) Melanomas: Correlation between Invasivity Markers and Dermoscopy
Dr. Olga Simionescu, Professor, Department of Dermatology, Colentina Hospital, Romania

14:45-15:10

Title: T Cell Immunoregulatory Antibodies in the Treatment of Metastatic Melanoma: CTLA-4 and Beyond
Dr. Steven O'Day, Chief of Research, Director of Melanoma Program, The Angeles Clinic and Research Institute, USA

15:10-15:35

Title: Regulation of Anti-tumor Immune Response by Interleukin-13 in a Murine T Cell Lymphoma
Dr. Arbind Acharya, Professor of Zoology, Centre of Advanced Study in Zoology, Banaras Hindu University, India

15:35-15:55

Coffee Break

 Session Chair:

Dr. Bertram Illert, General and Visceral Surgeon, Teaching Hospital of the Julius-Maximilians-University of Würzburg, Germany

Co-Chair:

Dr. Stephen Mahler, Associate Professor, Australian Institute of Bioengineering and Nanotechnology (AIBN), University of Queensland, Australia

13:30-13:50

Title: The Gastrin-releasing Peptide Receptor as a Target for Cervical Cancer Diagnosis 
Dr. Daniela Cornelio, Researcher, Complexo Hospitalar Santa Casa de Porto Alegre and Hospital de Clínicas de Porto Alegre, Brazil

 Session Chair:

Dr. Bertram Illert, General and Visceral Surgeon, Teaching Hospital of the Julius-Maximilians-University of Würzburg, Germany

Co-Chair:

Dr. Stephen Mahler, Associate Professor, Australian Institute of Bioengineering and Nanotechnology (AIBN), University of Queensland, Australia

13:50-14:10

Title: Anti-tumour Activity of Anti-CD48 Monoclonal Antibodies on Human Lymphoma Cells
Dr. Stephen Mahler, Associate Professor, Australian Institute of Bioengineering and Nanotechnology (AIBN), University of Queensland, Australia

 Session Chair:

Dr. Bertram Illert, General and Visceral Surgeon, Teaching Hospital of the Julius-Maximilians-University of Würzburg, Germany

Co-Chair:

Dr. Stephen Mahler, Associate Professor, Australian Institute of Bioengineering and Nanotechnology (AIBN), University of Queensland, Australia

14:10-14:30

Title: The Overall Reduction of Minimal Residual Disease with the Monoclonal Antibody PM-2 in a Metastasizing Gastric Cancer Model
Dr. Bertram Illert, General and Visceral Surgeon, Teaching Hospital of the Julius-Maximilians-University of Würzburg, Germany

14:30-14:50

Title: Aberrant Activation of Stem Cell Signaling Pathways in Esophageal Cancer
Dr. Biao He, Associate Professor, Thoracic Oncology Program, Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, USA

14:50-15:10

Title: CD105 Expression in Cancer Angiogenesis and Inhibition of Primary and Metastatic Cancer Lesions by Anti-CD105 Antibody in a Xenograft Model
Dr. Osamu Tokunaga, Professor and Chairman, Faculty of Medicine, Saga University, Japan

15:10-15:20

Coffee Break

 Session Chair:

Dr. Prabha Balaram, Professor, Dy. Director ( Post Graduate Affairs), Institute for Research in Molecular Medicine, Health Campus, Universiti Sains Malaysia, Malaysia

08:30-08:50

Title: Effectiveness of Contrast-enhanced Ultrasonography Using Perflubutane (SONAZOID) for Liver Resection after Bevacizumab plus FOLFOX Therapy
Dr. Hiroyuki Uetake, Associate Professor, Department of Translational Oncology, Graduate School, Tokyo Medical and Dental University, Japan

 Session Chair:

Dr. Prabha Balaram, Professor, Dy. Director ( Post Graduate Affairs), Institute for Research in Molecular Medicine, Health Campus, Universiti Sains Malaysia, Malaysia

08:50-09:10

Title: ¹³¹I-chTNT-1/B MAB (Cotara^®) Administered by Convection-enhanced Delivery for the Treatment of Malignant Gliomas of the Brain
Dr. William R. Shapiro, Chairman, Division of Neurology, Barrow Neurological Institute, USA

09:10-09:30

Title: Targeted Therapies in Head and Neck Cancer
Dr. Pol Specenier, Medical Oncologist, Antwerp University Hospital, Belgium

09:30-09:50

Title: Neurotrophin and Neuroendocrin Cell Surface Receptors in Head and Neck Squamous Cell Carcinoma
Dr. József Dudás, Research Fellow, Molecularbiology and Oncology Research Group, Department Otorhinolaryngology, Medical University Innsbruck, Austria

09:50-10:10

Title: Humoral Response to P53 - A Potential Target for Predicting Radiation Response in Oral Cancer
Dr. Prabha Balaram, Professor, Dy. Director ( Post Graduate Affairs), Institute for Research in Molecular Medicine, Health Campus, Universiti Sains Malaysia, Malaysia

10:10-10:30

Title: Galanin Receptor Subtype 1 as Therapeutic Targets and Prognosis Factor in Head and Neck Squamous Cell Carcinoma
Dr. Takeharu Kanazawa, Associated Professor, Department of Otolaryngology and Laboratory of Head and Neck Oncology, Jichi Medical University Saitama Medical Center, Japan

10:30-10:40

Coffee Break

 Session Chair:

Dr. Eva Honsova, Head of Pathology Department, Institute for Clinical and Experimental Medicine, Czech Republic

13:30-13:50

Title: Identification of Pathogen Targets for Anti-infective Monoclonal Antibodies
Dr. Martin Oleksiewicz, Head of Molecular Microbiology Department, Pre-clinical Research Division, Intercell AG, Austria

13:50-14:10

Title: The Role of Antibodies in the Resolution of Intracellular Bacterial Infection Caused by Gram-negative Bacterium Francisella Tularensis
Dr. Ales Macela, Professor, University of Defence, Faculty of Military Health Sciences, Czech Republic

14:10-14:30

Title: Antibodies against Calcium-release and -Influx Channels in Myasthenia Gravis and Therapeutic Strategy by FK506
Dr. Masaharu Takamori, Professor Emeritus of Kanazawa University,  Director of Neurological Center at Kanazawa-Nishi Hospital, Japan

14:30-14:50

Title: Antibody – Mediated Immunity: From Theory to Diagnosis of Humoral Rejection
Dr. Eva Honsova, Head of Pathology Department, Institute for Clinical and Experimental Medicine, Czech Republic

 Session Chair:

Dr. Huaxin (Larry) Liao, Professor of Medicine, Research Director, Duke Human Vaccine Institute, Duke University Medical Center, USA

08:30-08:50

Title: Polypeptide Recognized by Anti HIV-1 GP41 Antibodies Isolated from Highly HIV-1 Exposed, Non Infected Women
Dr. Regis Sodoyer, Head of Molecular Microbiology, Sanofi Pasteur - Research Department, France

08:50-09:10

Title: Profile B Cell Repertoires in Emerging Infections such as HIV-1 and Influenza for Development of Therapeutic Antibodies and Protective Vaccines
Dr. Huaxin (Larry) Liao, Professor of Medicine, Research Director, Duke Human Vaccine Institute, Duke University Medical Center, USA

09:10-09:30

Title: Targeting the Carbohydrates on HIV-1: Interaction of Oligomannose Dendrons with Human Monoclonal Antibody 2G12 and DC-SIGN
Dr. Pi-Hui Liang, Assistant Professor, National Taiwan University, Taiwan

09:30-09:50

Title: Rituximab Therapy for Castleman Disease
Dr. Makoto Ide, Staff Member of Hematology, Takamatsu Red Cross Hospital, Japan

09:50-10:10

Title: Structure and Epitopes of HIV Neutralizing Antibodies Revealed by Electron Microscopy
Dr. Ping Zhu, Professor, Institute of Biophysics, Chinese Academy of Sciences, China

10:10-10:20

Coffee Break

Session Chair:

Dr. Nobutaka Hattori, Professor, Department of Neurology, Juntendo University School of Medicine, Japan

Co-Chair:

 Dr. Paul J. Lockhart, Research Fellow, Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, The Royal Children's Hospital, Australia

15:20-15:40

Title: Monoclonal Antibodies Targeting the E1E2 Envelope Complex of Serum-derived Hepatitis C Virus Particles – Potential Diagnostic and Immuntherapeutic Applications
Dr. Marie-Anne Petit, Research Director, INSERM Unit 871, Hotel Dieu Hospital, France

 Session Chair:

Dr. Lionel Rostaing, Professor, Organ Transplant Unit, Toulouse University Hospital, France

Co-Chair:

Dr. Yasuhiko Sugawara, Associate Professor, University of Tokyo, Japan

08:30-08:50

Title: Polysaccharide Immune Globulins for Prevention of Invasive Diseases Caused by Encapsulated Bacterial Pathogens
Dr. Carl E Frasch, Biologics Consultant, Frasch Biologics Consulting Martinsburg, USA

 Session Chair:

Dr. Qiang Chen, Assistant Professor, The Biodesign Institute, Arizona State University, USA

15:55-16:20

Title: Development of a Plant-derived Therapeutic Mab for West Nile Virus Infections
Dr. Qiang Chen, Assistant Professor, The Biodesign Institute, Arizona State University, USA

16:20-16:45

Title: Fab Monoclonal Antibodies Specific to Hemagglutinin of H5N1 Influenza Virus with Neutralizing Activity Developed Using Phage Display Technique
Dr. Pongrama Ramasoota, Deputy Dean for Research and Innovation, Faculty of Tropical Medicine, Mahidol University, Thailand

 Session Chair:

Dr. Qiang Chen, Assistant Professor, The Biodesign Institute, Arizona State University, USA

16:45-17:10

Title: Exploiting Humoral Immunity: A Cure (and Diagnosis) for What Ails You
Dr. Jane M. Schuh, Assistant Professor of Immunology, North Dakota State University, USA

 Session Chair:

Dr. Pierre Lafaye, Group Leader, Pasteur Institute – Paris, France

14:50-15:10

Title: Cell Penetrating Anti-GFAP VHH Spontaneously Cross the Blood Brain Barrier and Recognize Specifically Astrocytes
Dr. Pierre Lafaye, Group Leader, Pasteur Institute – Paris, France

15:10-15:30

Title: Kinins as Possible Mediators of Astrocyte-inflammation
Dr. Sigal Fleisher-Berkovich, Professor, Ben-Gurion University of the Negev, Israel

15:30-15:50

Title: Consequences of Immune Complex Formation in the Brain
Dr. Jessica L. Teeling, Lecturer in Immunology and Neuroscience, School of Biological Sciences, University of Southampton, UK

15:50-16:00

Coffee Break

 Session Chair:

Dr. Ahmed El-Missiry, Associate Professor of Psychiatry and Consultant Psychiatrist, The Pagoda CMHC, Kent & Medway NHS Trust, UK

11:00-11:20

Keynote Speech:
Title: Promise and Challenges of Developing Safe and Effective Therapeutic Antibodies for Alzheimer's Disease
Dr. Daniel Chain, Chairman and CEO, Intellect Neurosciences, Inc., USA

11:20-11:40

Title: Affibody Ligands Binding to Alzheimer's Amyloid ß Peptides with Capacity to Inhibit Amyloid Formation
Dr. John Löfblom, Post-doctoral Fellow, Department of Molecular Biotechnology, School of Biotechnology, AlbaNova University Center, Royal Institute of Technology (KTH), Sweden

11:40-12:00

Title: Amyloid Beta Immunization Retards Formation of Abeta Plaques and Neurodegenerative Angiotensin II AT2 Receptor Oligomers
Dr. Ahmed El-Missiry, Associate Professor of Psychiatry and Consultant Psychiatrist, The Pagoda CMHC, Kent & Medway NHS Trust, UK

Session Chair:

Dr. Nobutaka Hattori, Professor, Department of Neurology, Juntendo University School of Medicine, Japan

Co-Chair:

Dr. Paul J. Lockhart, Research Fellow, Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, The Royal Children's Hospital, Australia

15:40-16:00

Title: Functional Analysis of Parkin and PACRG and Astrocytic Expression in Parkinsonian Disorders
Dr. Paul J. Lockhart, Research Fellow, Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, The Royal Children's Hospital, Australia

16:00-16:20

Title:  Pathogenesis of Parkinson's Disease: Insights from Monogenic Form of Familial Parkinson's Disease
Dr. Nobutaka Hattori, Professor, Department of Neurology, Juntendo University School of Medicine, Japan

16:20-16:40

Title: The Role of Proinflammatory Cytokines in Parkinson's Disease-induced Daytime Somnolence
Dr. Fang-Chia Chang, Associate Professor, Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taiwan

16:40-17:00

Title: Toxicity of Alpha-synuclein in Dopaminergic Cells: A Candidate of Therapeutic Target for Parkinson's Disease
Dr. Kazuhiro Nakaso, Assistant Professor, Division of Neurology, Department of Brain and Neurological Sciences, Faculty of Medicine, Tottori University, Japan

17:00-17:20

Title: Neuropathological Characterization of a Novel Mouse Model of Dementia with Lewy Bodies
Dr. Makoto Hashimoto, Head, Laboratory for Chemistry and Metabolism, Tokyo Metropolitan Institute for Neuroscience, Japan

17:20-17:40

Title: Autoantibodies in Epilepsy: Cause or Effect?
Dr. Tiziana Granata, Associated Staff, Department of Pediatric Neuroscience, National Neurological Institute C.Besta, Italy

 Session Chair:

Dr. Michael Maes, Professor, Maes Clinics, Belgium

10:40-11:00

Title: The Urinary Excretion of Biopyrrins, Oxidative Metabolites of Bilirubin, in Patients with Schizophrenia
Dr. Rei Wake (Yasukawa), Research Fellow, Shimane University School of Medicine, Japan

11:00-11:20

Title: Clinical Potential of Minocycline for Schizophrenia
Dr. Tsuyoshi Miyaoka, Associate Professor, Department of Psychiatry, Shimane University School of Medicine, Japan

11:20-11:40

Title: Introduction of Inflammatory and Oxidative and Nitro Sative Pathways in Major Depression and Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): Focus on Autoimmune Reactions
Dr. Michael Maes, Professor, Maes Clinics, Belgium

11:40-12:00

Title: New Trends on Neuro Immunological Basis of Schizophrenia
Dr. Evangelos Karanikas, Psychiatrist, Psychiatric Department, 424 General Military Hospital, Greece

 Session Chair:

Dr. Hongtao Lu, Head & Director, Neuroimmunology DPU, GSK R&D, China

Co-Chair:

Dr. Daniel Kantor, Medical Director, Neurologique, USA

13:30-13:50

Title: Targeting IL-7R for the Treatment of Multiple Sclerosis
Dr. Hongtao Lu, Head & Director, Neuroimmunology DPU, GSK R&D, China

13:50-14:10

Title: MRI-guided Immuneotherapy Development for Multiple Scleraosis in a Primate
Dr. Bert A 't Hart, Chairman, Immunobiology Department, Biomedical Primate Research Centre, The Netherlands

14:10-14:30

Title: Alemtuzumab and Its Role in MS: Therapeutic Update and Its Comparison to a Polyclonal Antibody, Aimspro
Dr. Daniel Kantor, Medical Director, Neurologique, USA

14:30-14:50

Title: Alemtuzumab Induces Significant Expansion of CD4+CD25+CD127- T_reg Cells Which Secrete TGFb in Patients with Relapsing Remitting Multiple Sclerosis 　
Dr. Xin Zhang, Research Associate, Department of Neurology and Dr. Silva Markovic-Plese, Associate Professor, Department of Neurology, Microbiology and Immunology, University of North Carolina (UNC) at Chapel Hill, USA

 Session Chair:

Dr. Kimihiro Okubo, Associate Professor, Department of Otolaryngology, Nippon Medical School, Japan

 Co-Chair:

 Dr. Jean Villard, Head, Immunology and Transplant Unit, Geneva University Hospital, Switzerland

16:00-16:20

Title: Antiangiogenic Protein Delivery Mediated by Viral Vectors
Dr. Keisuke Mori, Associate Professor of Ophthalmology, Saitama Medical University School of Medicine, Japan

16:20-16:40

Title: IL-6 in Autoimmune Disorders: How to Neutralize It
Dr. Fabiola Atzeni, Clinical Researcher, Rheumatology Unit, Department of Medicine, L Sacco University Hospital, Italy

16:40-17:00

Title: Opposite Effect of IL-21 Inhibition by a Novel Receptor Antagonist in Two Murine Model of Autoimmune Diseases
Dr. Sylvie Ferrari-Lacraz, Chief Resident, Immunology and Transplant Unit, Senior Research Associate, Division of Immunology and Allergy, University Hospital, Switzerland

 Session Chair:

Dr. Jun Nishihira, Professor, Hokkaido Information University, Japan

Co-Chair:

Dr. Kazuyuki Yoshizaki, Professor, Center for Advanced Science and Innovation, Osaka University, Japan

10:20-10:40

Title: Anti-IL-6 Receptor Mab (Tocilizumab) in RA: Role of IL-6 Blocking Therapy on the Improvement of RA
Dr. Kazuyuki Yoshizaki, Professor, Center for Advanced Science and Innovation, Osaka University, Japan

10:40-11:00

Title: Rituximab in Autoimmune Diseases: Long-term Treatment and Safety
Dr. Piercarlo Sarzi-Puttini, Director, Rheumatology Unit, L Sacco University Hospital, Italy 

11:00-11:20

Title: Therapeutic Use of Anti-MIF (Macrophage-migration Inhibitory Factor) Antibody for Systemic Inflammatory Disorders
Dr. Jun Nishihira, Professor, Hokkaido Information University, Japan

11:20-11:40

Title: Benefit Profile of Imunobiologics in Patients with Rheumatoid Arthritis, Ankylosing Spondylitis or Psoriatic Arthritis
Dr. Valderilio Feijó Azevedo, Professor, Department of Internal Medicine, Federal University of Paraná, Brazil

11:40-12:00

Title: Biological and Clinical Effects of Monoclonal Antibodies in an Ordinary Clinical Settings: Our Experience with Rheumatoid Arthrithis, Ankylosing Spondylitis and Psoriatic Arthritis
Dr. Simona Rednic, Professor, Head of Rheumatology Department, University of Medicine and Pharmacy “Iuliu Hatieganu”, Romania

12:00-12:20

Title: Blockade of Post-translational Acquirement of Chemotactic Property of Osteopontin
Dr. Yasuyuki Yokosaki, Director, Cell-Matrix Frontier Laboratory, Associate Professor, Health Administration Center, Hiroshima University, Japan

 Session Chair:

Dr. Ken Ohta, Professor, Department of Medicine, Teikyo University School of Medicine, Japan

 Co-Chair:

Dr. Naoto Watanabe, Research Fellow, Faculty of Pharmaceutical Sciences, Laboratory of Pharmacology, Josai International University, Japan

13:30-13:55

Title: Therapeutic Targeting of Beta1 Integrin for Tissue Repair
Dr. Rehab AlJamal Naylor, Principal Investigator, Senior Research Fellow, Co-founder AVIPERO Ltd., Pathology, MRC/CIR University of Edinburgh, The Queens Medical Research Institute, UK  

13:55-14:20

Title: Current and Potential Mabs for Asthma Therapy
Dr. Ying Sun, Reader and Principal Investigator, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, Division of Asthma, Allergy & Lung Biology, Guy's Hospital, UK

14:20-14:45

Title: Omalizumab Improves Asthma Control in Patients Receiving High-dose ICS and Multiple Other Controller Therapy and Who Have Continuing Impairment of Lung Function and Asthma Symptoms
Dr. Ken Ohta, Professor, Department of Medicine, Teikyo University School of Medicine, Japan

14:45-15:10

Title: Immunohistochemical Co-localization of Transient Receptor Potential Vanilloid-1 in the Trachea Using a Guinea-pig Asthma Model
Dr. Naoto Watanabe, Research Fellow, Faculty of Pharmaceutical Sciences, Laboratory of Pharmacology, Josai International University, Japan

15:10-15:25

Coffee Break

15:25-15:50

Title: The Role of Monoclonal Antibodies for Respiratory Syncytial Virus Infections
Dr. Sandra Vieira, Professor, Department of Pediatrics, Faculty of Medicine, University of São Paulo, Brazil

 Session Chair:

Dr. Lionel Rostaing, Professor, Organ Transplant Unit, Toulouse University Hospital, France

Co-Chair:

Dr. Yasuhiko Sugawara, Associate Professor, University of Tokyo, Japan

08:50-09:10

Title: Antibody-mediated Renal Allograft Rejection: Diagnosis and Management Strategies
Dr. Mohamed El-Shahawy, Professor of Medicine, University of Southern California, USA

09:10-09:30

Title: The Use of Rituximab in Kidney-transplant Patients: An Update
Dr. Lionel Rostaing, Professor, Organ Transplant Unit, Toulouse University Hospital, France

09:30-09:50

Title: Experience with Alemtuzumab (Campath-1H) as Induction Agent in Renal Transplantation Followed by Steroid-free Immunosuppression
Dr. Fernando Girón L., Director Científico, Colombiana de Trasplantes, Colombia 

09:50-10:10

Title: Interleukin-2 Receptor Antibody Therapy as an Induction or Rescue after Acute Rejection after Liver Transplantation
Dr. Yasuhiko Sugawara, Associate Professor, University of Tokyo, Japan

10:10-10:30

Coffee Break

 Session Chair:

Dr. Jinquan (Jeffrey) Luo, Principal Research Scientist, Centocor R&D, Inc., USA

 Co-Chair:

Dr. Katherine Li, Research Scientist, Centocor R&D, Inc, USA

13:30-13:50

Title: Structural Studies of Ustekinumab and Its Interactions with the p40 Subunit of IL-12 and IL-23
Dr. Jinquan (Jeffrey) Luo, Principal Research Scientist, Centocor R&D, Inc., USA

13:50-14:10

Title: The Molecular Profile of Psoriatic Skin in Responders to Ustekinumab or Etanercept Following Twelve Weeks of Treatment: Results from the ACCEPT Trial
Dr. Katherine Li, Research Scientist, Centocor R&D, Inc, USA

14:10-14:30

Title: Nuclease Deficiencies May Promote Progression of Lupus Nephritis but not Nephritogenic Autoimmunity
Dr. Ole Petter Rekvig, Professor, University of Tromsø, Norway

14:30-14:50

Title: Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW) F1 Mice
Dr. Elin S Mortensen, Professor, University of Tromsø, Norway

14:50-15:10

Title: The Relation between Estrogen Level, Anti-Ro (SSA), Anti-La (SSB) & Secondary Sjogren's Syndrome Patients
Dr. Basma Mustafa, Assistant Professor, College of Dentistry, International Islamic University Malaysia, Malaysia

15:10-15:30

Coffee Break

15:30-15:50

Title: Serum IL-17 and IL-23 Levels in Patients with Systemic Lupus  Erythematosus and Their Relation with Clinical Features
Dr. Nurşen Düzgün, Department of Clinical Immunology and Rheumatology, Ankara University, Faculty of Medicine, Turkey

15:50-16:10

Title: Proteomic Microarray for Autoantibody Profiling and for the Discovery of New Biomarkers of the Autoimmune Diseases 
Dr. Quan-Zhen Li, Assistant Professor of Immunology, Head of Microarray Core Facility, University of Texas Southwestern Medical Center, USA

 Session Chair:

Dr. Junjian Liu, Senior Scientist, Abbott Bioresearch Center, USA

16:10-16:30

Title: Construction and Optimization of Anti-human IL-1α/β Dual Variable Domain Immunoglobulin (DVD-Ig^TM) Molecules
Dr. Junjian Liu, Senior Scientist, Abbott Bioresearch Center, USA

16:30-16:50

Title: Autoantibodies in Human Reproduction
Dr. Hidehiko Matsubayashi, Associate Professor, Osaka New ART Clinic, Japan

16:50-17:10

Title: Low Levels of IgM Antibodies against Phosphorylcholine-A Predict Mortality Risk in Patients Undergoing Haemodialysis
Dr. Xiang Hua, Department of Medicine, Karolinska University Hospital, Sweden

 Session Chair:

Dr. Kimihiro Okubo, Associate Professor, Department of Otolaryngology, Nippon Medical School, Japan

 Co-Chair:

Dr. Jean Villard, Head, Immunology and Transplant Unit, Geneva University Hospital, Switzerland

17:00-17:20

Title: Allo and Autoantibodies after Solid Organ and Hematopoietic Stem Cells Transplantation
Dr. Jean Villard, Head, Immunology and Transplant Unit, Geneva University Hospital, Switzerland

17:20-17:40

Title: Omalizumab Update in Allergic Rhinitis
Dr. Kimihiro Okubo, Associate Professor, Department of Otolaryngology, Nippon Medical School, Japan

17:40-18:00

Title: Towards a Pan-anti-allergic Vaccine
Dr. Birgit A. Helm, Krebs Institute for Biomolecular Research, Department of Molecular Biology and Biotechnology, University of Sheffield, UK

 Session Chair:

Dr. Lucia C.J. Abel, Professor, Paulista University, Brazil

11:00-11:20

Title: MAbs against Crohn's Disease, and Other Severe G.I. Disorders
Dr. Alojz Ihan, Professor & Director, Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia

11:20-11:40

Title: mAbs and Vaccines against Cytokines in the Treatment of Crohn's Disease and Other GI Diseases
Dr. Zhikang Peng, Professor, University of Manitoba, Canada

11:40-12:00

Title: Early Versus Late Anti-TNF Alpha Treatment in Crohn's Disease: Applying Clinical Data to Clinical Practice
Dr. Alessandro Armuzzi, Consultant Physician, Gastroenterology Unit – Complesso Integrato Columbus, Catholic University of Rome, Italy

12:00-12:20

Title: Granulocyte-monocyte Adsorption and Mabs Treatment in Inflammatory Bowell Disease: Mechanisms of Action and Immunomodulatory Effects
Dr. Juan Muñoz, Physician Haematologist, Blood Bank and Tissues, Bellvitge Hospital, Spain

12:20-12:40

Title: Coeliac Disease and Pregnancy
Dr. Anjum Naheed, Consultant Obstetrician and Gynaecologist, The Leeds Teaching Hospitals, UK

 Session Chair:

Dr. Ken Ohta, Professor, Department of Medicine, Teikyo University School of Medicine, Japan

 Co-Chair:

Dr. Naoto Watanabe, Research Fellow, Faculty of Pharmaceutical Sciences, Laboratory of Pharmacology, Josai International University, Japan

15:50-16:15

Title: Novel Antiplatelet Antibody, mF1232, Inducing Endocytosis of the GPVI/Fc Receptor γ-chain Complex
Dr. Motoyasu Honda, Scientist, Discovery Research, Mochida Pharmaceutical Co., Ltd., Japan

 Session Chair:

Dr. Lionel Rostaing, Professor, Organ Transplant Unit, Toulouse University Hospital, France

Co-Chair:

Dr. Yasuhiko Sugawara, Associate Professor, University of Tokyo, Japan

10:30-10:50

Title: Relationship between Sodium Iodide Symporter & Thyroid Peroxidase and Proapoptotic (TIAR and TIA-1) Markers Detection in Thyrocytes from Adolescents with Autoimmune and Nonautoimmune Thyroid Diseases
Dr. Artur Bossowski, Professor, Head of Department of Pediatric, Endocrinology, Diabetology with Cardiology Division, Medical University in Bialystok, Poland 

 Session Chair:

Dr. Winfried Amoaku, Chairman of the Scientific Committee, Royal College of Ophthalmologists, UK

14:50-15:10

Title: Comparisons of Phenotype and Effects of Anti-VEGFs on Human Retinal and Choroidal Endothelial Cells
Dr. Winfried Amoaku, Chairman of the Scientific Committee, Royal College of Ophthalmologists, UK

15:10-15:30

Title: Characterization of Apoptosis-specific Antibodies in the Drosophila Eye
Dr. Andreas Bergmann, Associate Professor, Department of Biochemistry & Molecular Biology, MD Anderson Cancer Center, USA

15:30-15:40

Coffee Break

15:40-16:00

Title: MAbs in the Treatment of Age-related Macular Degeneration, Choroidal Neovascularization (CNV) and Other Eye Diseases
Dr. Polly Quiram, Vitreoretinal Surgeon, Vitreoretinal Surgery, USA

16:00-16:20

Title: Pathophysilological Roles of Anti-neuron Specific Enolase in Glaucoma and Its Diagnostic and Therapeutic Applications
Dr. Hiroshi Ohguro, Professor, Department of Ophthalmology, Sapporo Medical University School of Medicine, Japan

16:20-16:40

Title: Anti-TNF Therapy for Retinal Diseases
Dr. Fabrizio Giansanti, Researcher, Department of Oto-Neuro-Ophthalological Surgical Sciences, Eye Clinic, University of Florence, Italy

 Session Chair:

Dr. Yoshimi Kuroiwa, CSO & Director of Molecular Genetics Department, Hematech, Inc., USA

13:30-13:50

Title: The Management of Metastatic Pancreatic and Colorectal Ca Using Specific Monoclonals Targeting Immunogenic TAA
Dr. Myron Arlen, Chief Executive Officer, Neogenix Oncology Inc, USA

Session 8-2: Antibody Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety

 Session Chair:

Dr. Tristan Rousselle, CEO, PX'Therapeutics SA, France

16:40-17:00

Title: Challenges in Therapeutic Antibodies Development, from Bench to GMP Batches Production
Dr. Tristan Rousselle, CEO, PX'Therapeutics SA, France

17:00-17:20

Title: Engineered Monoclonal Antibodies for Therapeutic and in vivo Diagnostics Use: Design, Synthesis and Production
Dr. Walter Low, Director of Antibody Engineering and Development, PX'Therapeutics, France

17:20-17:40

Title: Development of Therapeutic mAb in Bacterial Infectious Diseases
Dr. Anne Marie Di Guilmi, Research Fellow, Institute for Structural Biology, France

Title: A Case Study on a Humanized Monoclonal Antibody Development
Dr. Jiewei Wei, CEO, Australian Biobest Biotechnology Service, Australia

 Session Chair:

Dr. Laura Caponi, Assistant Professor, Laboratory of Specialized Analysis, Department of Laboratory Medicine and Molecular Biology, Azienda Ospedaliero-Universitaria Pisana, Italy

Co-Chair:

 Dr.Zhichao Pei, Professor, College of Science , Northwest A&F University，China

15:30-15:50

Title: New Autoantigens in Rheumatoid Arthritis: Diagnostic Tools and Insight into Pathogeny
Dr. Jean Roudier, Professor of Medicine, University of Mediterranée, France

15:50-16:10

Title: Multiple Autoantibody Cross-reactivity in Connective Tissue Diseases
Dr. Laura Caponi, Assistant Professor, Laboratory of Specialized Analysis, Department of Laboratory Medicine and Molecular Biology, Azienda Ospedaliero-Universitaria Pisana, Italy

16:10-16:30

Title: Optimizing Immobilization Conditions on a Two Dimensional Carboxyl Biosensor Surface: pH Dependence of Antibody Orientation and Antigen Binding Capacity
Dr. Zhichao Pei, Professor, College of Science , Northwest A&F University, China

16:30-16:50

Title: An Electrochemical Immunoassay for Protein Based on Bio Bar Code Method
Dr. Shusheng Zhang, Professor, Qingdao University of Science and Technology, China

16:50-17:10

Title: A Standardized Target-based ELISA without Matrix Interferences for Pharmacokinetic Studies of Therapeutic Monoclonal Antibodies
Dr. Julie Doucet, BMD/MLA, Novartis Pharma AG, Switzerland

17:10-17:30

Title: Opportunities and Challenges of Biomarker Assays in Drug Development
Dr. Alexandre Avrameas, Immunoassays Biomarker Head, Novartis Institutes for Biomedical Research/ Translational Sciences / BMD, Switzerland

Session
Chair:

Dr. Bailin Tu, Principal Scientist, Antibody Research, Abbott Laboratories, USA

Co-Chair:

Dr. Karlheinz Peter, Professor of Medicine and Immunology, Monash University, ARC Future Fellow, NHMRC Honorary Fellow, Head, Atherothrombosis & Vascular Biology, Associate Director, Baker IDI Heart & Diabetes Institute, Senior Interventional Cardiologist, The Alfred Hospital, Australia

13:30-13:50

Title: The HE4 Time-resolved Fluoroimmunoassay (TR-FIA) Kit for Ovarian Cancer
Dr. Fenfang Wu, CEO, Dalian Medabs Biotech Co., Ltd., China

13:50-14:10

Title: Prognostic Significance of Monoclonal Antibodies in Head and Neck Tumors
Dr. Elvir Zvrko, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Montenegro, Yugoslavia

14:10-14:30

Title: Antibody Engineering for Diagnostics: Anti-HCV Chimeric Antibodies
Dr. Bailin Tu, Principal Scientist, Antibody Research, Abbott Laboratories, USA

14:30-14:50

Title: Evaluation of Antibody Responses in Mycobacterial Diseases with Special Emphasis on Secretory Antigens
Dr. Beenu Joshi, Scientist, National JALMA Institute for Leprosy and OMD, India

14:50-15:10

Title: The Diagnostic Value of Autoantibodies in Childhood Neuroimmunology
Dr. Helene Verhelst, Pediatric Neurologist, Ghent University Hospital, Belgium

15:10-15:20

Coffee Break

15:20-15:40

Title: Conformation-specific Anti-platelet Single-chain Antibodies:
Unique Biotechnological Tools for Effective Anti-thrombotic Therapy with Less Bleeding and Molecular Imaging of Inflammation and Vulnerable Atherosclerotic Plaques
Dr. Karlheinz Peter, Professor of Medicine and Immunology, Monash University, ARC Future Fellow, NHMRC Honorary Fellow, Head, Atherothrombosis & Vascular Biology, Associate Director, Baker IDI Heart & Diabetes Institute, Senior Interventional Cardiologist, The Alfred Hospital, Australia

15:40-16:00

Title: Selection and Engineering of Antibody Fragments for Cardiovascular Disease POC Platforms
Dr. Paul Leonard, Lecturer, School of Biotechnology, Principal Investigator, Biomedical Diagnostics Institute, National Centre for Sensor Research, Dublin City University, Ireland

 Session Chair:

Dr. Yoshimi Kuroiwa, CSO & Director of Molecular Genetics Department, Hematech, Inc., USA

13:50-14:10

Title: Production of Human Polyclonal Antibodies in Transgenic Cattle
Dr. Yoshimi Kuroiwa, CSO & Director of Molecular Genetics Department, Hematech, Inc., USA

14:10-14:30

Title: Molecular Biofarming of Therapeutic Proteins in Heterologous Expression System
Dr. Kisung Ko, Assistant Professor, (Adjunct Researcher of KRIBB), Department of Biological Science, College of Natural Sciences, Wonkwang University, Korea

14:30-14:50

Title: Disposable, Orbitally Shaken Bioreactor
Dr. Tibor Anderlei, Head of Science and Business Development, Adolf Kühner AG, Switzerland

14:50-15:10

Title: Profiling of Surface Proteome and Discovering New Surface Markers of Embryonic Stem Cells with Proteomics and Monoclonal Antibody Methods
Dr. Ming Zhang, Professor, College of Life Science, Zhejiang University, China

15:10-15:30

Coffee Break

Session Chair:

Dr. Judith Zhu-Shimoni, Scientist, Genentech, Inc., USA

Co-Chair:

Dr. Wai Lam W. Ling, Cell Culture and Fermentation Development, Biological and Sterile Product Development, Schering-Plough Research Institute, USA

08:30-08:35

Welcome Introduction

08:35-09:00

Keynote speech
Title: Optimization of Antibody Expression Using Regulatory Control Elements
Dr. Dennis W Harris, Corporate VP and CSO, Millipore Corporation, USA

09:00-09:20

Title: Efficient Screening for Mammalian Cell Clones Producing High and Stable Antibody Titers
Dr. Christopher J. Mann, Senior Application Support Specialist, Genetix , UK

09:20-09:40

Title: Cell Culture Process Development, Optimization, Characterization and Profiling for the Enhancement of Monoclonal Antibody Production for CHO Cells
Dr. Wai Lam W. Ling, Cell Culture and Fermentation Development, Biological and Sterile Product Development, Schering-Plough Research Institute, USA

09:40-10:00

Title: Mass Production of Monoclonal Antibodies Using Multi-stage Continuous High Cell Density Culture (MSC-HCDC)  Bioreactor System
Dr. Ho Nam Chang, Professor, KAIST(Korea Advanced Institute of Science and Technology), Korea (Republic of )

10:00-10:20

Title: Wave Reactor: The Modern Tool for Mab Production
Dr. Mariana Henriques, Invited Assistant Professor, Department of Biological Engineering, University of Minho, Portugal

10:20-10:30

Coffee Break

10:30-10:50

Title: Novel Approaches to Titer Determination
Dr. Judith Zhu-Shimoni, Scientist, Genentech, Inc., USA

10:50-11:10

Title: Production of Full-length Antibody in Methylotrophic Yeast Ogataea Minuta
Dr. Yoshifumi Jigami, Invited Senior Researcher of RCMG and Principal Reviewer of Evaluation Department, National Institute of Industrial Science and Technology (AIST), Japan

11:10-11:30

Title: Production of Monoclonal Antibodies against a Shared AgB/8 Peptide of Echinococcus Granulosus Strains for Diagnostic Purposes
Dr. Khaled M. Al-Qaoud, Department of Biotechnology and Genetic Engineering, Philadelphia University, Jordan

11:30-11:50

Title: Application of Anion Exchanger in Recovery of Rabbit Polyclonal Immunoglobulin G
Dr. Tau Chuan Ling, Associate Professor, Department of Process and Food Engineering, Faculty of Engineering, Universiti Putra Malaysia, Malaysia

11:50-12:10

Title: Shaker Technology for the Cultivation of Cells in Suspension
Dr. Ang Guan, Sales Engineer, Shanghai Bioscienti Co., China

 Session Chair:

Dr. Pete Gagnon, CSO, Validated Biosystems, USA

16:00-16:20

Title: Improvements in the Quality of BioSimilars by Application of Enhanced Washing and Elution Procedures for Protein a Affinity Chromatography
Dr. Pete Gagnon, CSO, Validated Biosystems, USA

16:20-16:40

Title: Hydroxyapatite in Downstream Processing, Matrix Stabilization
Dr. Larry J. Cummings, Consulting Scientist , Bio-Rad Laboratories, Inc., USA

16:40-17:00

Title: Rational Design of Ligand Protein That Ensures Optimum pH-Response in Affinity Purification of Antibody
Dr. Shinya Honda, Research Group Leader, National Institute of Advanced Industrial Science and Technology (AIST), Japan

17:00-17:20

Title: Applications of Integrated Biotechnology in Recombinant Protein Production
Dr. Wang-Yu Tong, Professor, Anhui University, China

 Session Chair:

Dr. Kevin W. McCabe, Director, Sterne, Kessler, Goldstein & FoxP. L.L.C, USA

10:50-11:10

Title: The U.S. Biosimilar Regime: How Foreign Companies Will Compete
Dr. Kevin W. McCabe, Director, Sterne, Kessler, Goldstein & FoxP. L.L.C, USA

11:10-11:30

Title: Use of Autologous IL-1ra and Other Cytokines in Orthopedics: The Orthokine Therapy
Dr. David W. Hang, Assistant Clinical Professor of Orthopedic Surgery, University of California at Los Angeles, Director, Shin Kong Orthopedic Sports Medicine Institute, Taiwan

11:30-11:50

Title: Technological Platform for Innovative and Biosimilar Antibodies: An Alternative Approach from the Cuban Biotech
Dr. Ernesto Chico, Technical Director, Center of Molecular Immunology, Cuba

Session Chair:

Dr. Rolf Werner, Corporate Senior Vice President, Biopharmaceuticals, Boehringer Ingelheim GmbH, Germany

15:50-16:15

Keynote Speaker:
Title: Regulatory Strategy for Development of Therapeutic Antibodies for Cancer - Making the Most of Your Clinical Trial Dollars
Dr. Evan B. Siegel, President and CEO, Ground Zero Pharmaceuticals, Inc., USA

16:15-16:40

Title: The Opportunity for Next-Generation Antibody Development Platforms
Mr. Hamza Suria, Vice President, Corporate Development, AnaptysBio, Inc., USA

16:40-17:05

Title: Time to Market Development and Manufacturing of Biopharmaceuticals
Dr. Rolf Werner, Corporate Senior Vice President, Biopharmaceuticals, Boehringer Ingelheim GmbH, Germany