Time: May 22-24, 2009
Place: Beijing Continental Grand Hotel ( Beijing International Convention Center ), China

May 21, 2009 (Thursday)

May 22, 2009 (Friday)
Opening Ceremony and Keynote Forum

Time

Activities

May 22, 2009
(Friday)
9:00-9:35

Opening Ceremony

May 22, 2009
(Friday)
9:35-11:35

Session Chair:

Dr. Minzhen Xu, Vice President, Biology, Antigen Express, Inc., USA

Co-Chair:

Dr. Olivier Heudi, Laboratory Head, Novartis Institute for Biomedical Research, Translational Sciences DMPK/Bioanalytics, Switzerland

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: LC-MS/MS Absolute Quantification of Therapeutic Monoclonal Antibody in Biological Fluids: Where Do We Stand?
Dr. Olivier Heudi, Laboratory Head, Novartis Institute for Biomedical Research, Translational Sciences DMPK/Bioanalytics, Switzerland

14:00-14:25

Title: Ii-Key Hybrid Enhances the Epitope-specific Antibody Production: A Novel Vaccine Technology for Infectious Diseases and Cancers
Dr. Minzhen Xu, Vice President, Biology, Antigen Express, Inc., USA

14:25-14:50

Title: The Application of Protein Microarray Technology for Novel Therapeutic Monoclonal Antibody Discovery and Validation
Dr. Donghui Ma, Scientist Group Leader and Director, OriGene Technologies Inc., USA

14:50-15:15

Title: High Throughput Antibody Generation and Antibody-based Proteomics
Dr. Guozhen Liu,

15:15-15:30

Coffee Break

Session 1-6: Molecular Biology Applied To Antibody Characterization

Session Chair:

Dr. Jian Han, Faculty Investigator, HudsonAlpha Institute for Biotechnology, USA

15:30-15:35

Welcome: Session Introduction

15:35-16:00

Title: Structural Biology Applied to Therapeutic Antibody Design and Characterization
Dr. Faming Zhang, President, Crown Bioscience Inc., P.R. China

16:00-16:25

Title: Immunorepertoireomics: Studying Immunoglobulin Superfamily Molecules with Multiplex PCR and High Throughput Sequencing
Dr. Jian Han, Faculty Investigator, HudsonAlpha Institute for Biotechnology, USA

16:25-16:50

Title: Application of Phosphorylation and Acetylation Sites-specific Antibodies for Studies of Tumor Suppressor RB Protein and p53
Dr. Yoichi Taya, Professor, Cancer Science Institute of Singapore, National University of Singapore, Singapore

16:50-17:15

Title: Development of Antibody to Peptide Fragments or Small Molecules for Immunodiagnostic Applications
Dr Chen Situ, Lecturer in Drug, School of Biological Sciences, Queen's University Belfast, UK

17:15-17:30

Discussion

Session Chair:

Dr. Leodevico (Vic) L. Ilag, COO, Patrys Ltd, Australia

Co-Chair:

Dr. Rainer Hillenbrand, BM Group Head, Novartis Institute. of Biomed. Res. (CNIBR), P.R. China

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: Recent Advance in Hybridoma Technology
Dr. Masahiro Tomita, Professor, Mie University, Japan

09:30-09:55

Title: Generation and Characterization of High Affinity Antibodies from XenoMouse® Technology
Dr. Palaniswami Rathanaswami, Senior Scientist, Amgen British Columbia, Canada

09:55-10:20

Title: Natural Human Antibodies in Treating Disease
Dr. Leodevico (Vic) L. Ilag, COO, Patrys Ltd, Australia

10:20-10:35

Coffee Break

10:35-11:00

Title: Tool Antibodies for Biomarker Assays
Dr. Rainer Hillenbrand, BM Group Head, Novartis Institute. of Biomed. Res. (CNIBR), P.R. China

11:00-11:25

Title: A Genetic Engineered Single Chain Antibody against Hepatocellular Carcinoma and Its Nano Formulation
Dr. Yan-Fang Liu, Professor, Pathology Depart Pathology and Lab. Tumor Biology, Fourth Military Medical University, P.R. China

11:25-11:50

Title: Application of Hybridoma Technology for the Detection of Candida Antigens in Experimental Systemic Candidiasis Model
Dr. Wong Shew Fung, International Medical University, Malaysia

11:50-12:15

Title: HAUSP(USP7) Gene Clone and Preparation of Its Monoclone Antibody
Dr. Shaonong Wang, CTO, Chengdu Sinogen Biotechnology Inc., P.R. China

Session Chair:

Dr. Tony Warford, Discipline Leader, Histopathology, AstraZeneca, Innovation Center, P.R. China

Co-Chair:

Dr. Zhenxin Wang, Professor, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, P.R. China

13:30-13:35

Welcome: Session Introduction

13:35-14:05

Title: The Applications of Antibodies to Nanotechnology-based Diagnostics, Targeting and Nanoarrays
Dr. Bob Irving, COO, Nanotechnology Victoria Ltd, Australia

14:05-14:35

Title: Monoclonal Antibodies in Diagnostic, Predictive and Therapeutic Medicine
Dr. Tony Warford, Discipline Leader, Histopathology, AstraZeneca, Innovation Center, P.R. China

14:35-15:05

Title: Development and Application of Gold Nanoparticle-labelled Microarray
Dr. Zhenxin Wang, Professor, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, P.R. China

15:05-15:20

Coffee Break

15:20-15:50

Title: Surface Plasmon Resonance Imaging (SPRI) Antibody Array in Biomarker Discovery
Dr. Zhiyuan Hu, Research Scientist, Institute for Systems Biology, Seattle, USA

15:50-16:20

Title: Development of a New Phage Display System for the Screening of Antibody Fragments Suitable for Open-sandwich Immunoassay
Dr. Jinhua Dong, Research Fellow, Biorecognition Molecular Engineering Laboratory (Ueda lab.), The University of Tokyo, Japan

16:20-16:50

Title: Novel Single-chain Fv Antibody-immobilized Polystyrene Supports: Its Potential and Possibility for Antibody Microarray
Dr. Yoichi Kumada, Assistant Professor, Kyoto Institute of Technology, Japan

16:50-17:20

Discussion

Session Chair:

Dr. Larry (Huaxin) Liao, Professor of Medicine, Research Director, Duke Human Vaccine Institute, Duke University Medical Center, USA

Co-Chair:

Dr. Mei-Yun Zhang, Scientist, CCRNP, NCI-Frederick, NIH, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: The Development of a Genetic In-cell Affinity Maturation System Using Human B Cells for Antibodies and Other Protein-based Reagents
Dr. Bob Irving, COO, Nanotechnology Victoria Ltd, Australia

09:30-09:55

Title: The Evolution of Human Combinatorial Antibody Libraries (HuCAL®) and the Development of a HuCAL GOLD® Antibody for the Treatment of
Inflammatory Diseases
Dr. Christian Kunz, Project Team Leader, MorphoSys, Germany

09:55-10:20

Title: Construction of Human Antibody Fab Library from HIV-1-positive Individuals and Identification of HIV-1 Neutralizing Human Monoclonal
Antibodies
Dr. Mei-Yun Zhang, Scientist, CCRNP, NCI-Frederick, NIH, USA

10:20-10:35

Coffee Break

10:35-11:00

Title: High-throughput Isolation and Expression of Immunoglobulin Genes from Single Human B Cells as Monoclonal Antibodies
Dr. Larry (Huaxin) Liao, Professor of Medicine, Research Director, Duke Human Vaccine Institute, Duke University Medical Center, USA

11:00-11:25

Title: Generation of Antibody Gene Libraries for the Selection of Antibodies for Proteomics, Diagnosis and Therapy
Dr. Michael Hust, Postdoc, Group leader, Institut für Biochemie und Biotechnologie, Technische Universität Braunschweig, Germany

11:25-11:50

Title: Efficient Generation of Monoclonal Antibodies against Multiple-transmembrane Proteins such as GPCR and ABCT Using Sendai Virus Vector
Dr. Makoto Inoue, Director, General Manager, Department of Science & Technology Development, DNAVEC Corporation, Japan

11:50-12:15

Title: Rapid Lead Identification of Human Therapeutic Antibodies from Phage Display Libraries
Dr. David R. Buckler, Director, Alliance Research, Dyax Corp, USA

Session Chair:

Dr. Paul M Watt, VP, Research, Phylogica Ltd, Australia

Co-Chair:

Dr. Yu-Cai Liao, Professor, Huazhong Agricultural University, P.R. China

13:30-13:35

Welcome: Session Introduction

13:35-14:05

Title: Phylomers: Peptides Derived from Biodiverse Genomes, as Blockers for Intracellular as well as Extracellular Targets
Dr. Paul M Watt, VP, Research, Phylogica Ltd, Australia

14:05-14:35

Title: Single-chain Antibodies and Their Fusions for Prevention of Fusarium Mycotoxins at Fountainhead Point in Food/Feed Chains
Dr. Yu-Cai Liao, Professor, Huazhong Agricultural University, P.R. China

14:35-15:05

Title: Mini-antibodies, Immunoconjugates for Elimination of Cancer Cells and Phytopathogenic Fungi: Different Targets, But Equal Strategy
Dr. Elena Glinka, Senior Scientist, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences (IBCH RAS), Russia

15:05-15:20

Coffee Break

15:20-15:50

Title: Development of Small Antibody-like Proteins for Cancer Therapies
Dr. Hongtao Zhang, Research Assistant Professor, University of Pennsylvania, School of Medicine, USA

15:50-16:20

Title: Human Catalytic Antibody Se-Scfv-D8 with High Glutathione Peroxidase Activity
Dr. Jingyan Wei, Professor, College of Pharmacy, Jilin University, P.R. China

16:20-16:50

Title: Production of Metal Ion-Dependent Monoclonal Antibodies Against Peptides in Bovine Prothrombin Fragment 1
Dr. Sawsan Mahassni, Assistant Professor, King Abdulaziz University, Saudi Arabia

16:50-17:20

Discussion

Session Chair:

Dr. Cathy Chang, Vice President, Scientific Programs and Collaborations, BioAtla, LLC., USA

Co-Chair:

Dr. Marie-Paule Lefranc, IMGT Founder and Director, Professor University Montpellier 2, Senior Member of the Universitary Institute, France

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: A Novel Fully Human Monoclonal Antibody Platform Using Transgenic Rats
Dr.Roland Buelow, CEO, OMT Inc., USA

09:30-09:55

Title: Rapid Humanization and Affinity Improvement of a Murine Antibody
Dr. Cathy Chang, Vice President, Scientific Programs and Collaborations, BioAtla, LLC., USA

09:55-10:20

Title: IMGT Databases and Tools for Antibody Engineering and Humanization
Dr. Marie-Paule Lefranc, IMGT Founder and Director, Professor University Montpellier 2, Senior Member of the Universitary Institute, France

10:20-10:35

Coffee Break

10:35-11:00

Title: Humanization of a Highly Stable Anti-lysozyme scFv Endowed with Intracellular Functionality. A Single Framework Residue Dramatically Affects Protein Expression and Stability
Dr. Marcello Donini, Research Scientist, ENEA – Casaccia, Italy

11:00-11:25

Title: WuxiAppTec's Reagent Generation and Biologics Capabilities
Dr. ChiChang Lee, Senior Director, WuxiAppTec Co.,Ltd, P.R. China

11:25-11:50

Title: Immunogenicity Assessment Strategies at Bridge Laboratories to Support the Development of Biological Therapeutics
Dr. Michael (Linglong) Zou, Director of Immunology and Assay Support, Bridge Laboratories, P.R. China

11:50-12:00

Discussion

Session Chair:

Dr. Yifan Ma, Associate Professor, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, P.R. China

Co-Chair:

Dr. Stéphane Birklé, Associate Professor, University of Nantes, France

13:30-13:35

Welcome: Session Introduction

13:35-13:55

Title: Anti-CD146 Antibody Inhibites Angiogenesis and Its Mechanism
Dr. Xiyun Yan, Vice Director, Institute of Biophysics, Chinese Academy of Sciences, P.R. China

13:55-14:15

Title: Validation of Antibody Drug Targets and Interventions
Dr. Mayra Ramos Suzarte, Professor, Head, Clinical Trial Department, Clinical Research Direction, Center of Molecular Immunology, Cuba

14:15-14:35

Title: Cytostatic and Proapoptotic Properties of a Monoclonal Antibody Specific for O-acetylated GD2
Dr. Stéphane Birklé, Associate Professor, University of Nantes, France

14:35-14:55

Title: Evaluating the Immunoregulatory and Reactogenic Effects of Therapeutic Antibodies Using the Modular IMmune In Vitro Construct (MIMICTM) Technology
Dr. Yifan Ma, Associate Professor, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, P.R. China

14:55-15:10

Coffee Break

15:10-15:30

Title: Anti-bFGF Antibody, a Potential Antibody Drug against Tumor Angiogenesis
Dr. Deng Ning, Professor, Antibody Engineering Center, Jinan University, P.R. China

15:30-15:50

Title: BAFF, a Promising Target for Treating Autoimmune Diseases
Dr. Jian Sun, Associate Professor, Tianjin University, P.R. China

Session 3-1: Immunogenicity and Antibodies as Immunodiagnostics

Session Chair:

Dr. Xiaoying Zhang, Professor, Northwest A & F University, P.R. China

15:50-15:55

Welcome: Session Introduction

15:55-16:15

Title: Diagnosis of Antibody-mediated Platelet Disorders
Dr. Aaron Tomer, Professor of Medicine, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel

16:15-16:35

Title: Development of Assays for the Detection of Agents with Bioterroristic Potency Using the Igy-technology
Dr. Xiaoying Zhang, Professor, Northwest A & F University, P.R. China

16:35-16:55

Title: Rheumatoid Factor (RF) Production is Regulated by PIR-B on B-1 Cells and Its Excessive Elevation Can Link to Autoimmunity
Dr. Toshiyuki Takai, Professor, Institute of Development, Aging and Cancer, Tohoku University, Japan

16:55-17:15

Title: Strategies for Immunogenicity Assessment and Avoidance of Therapeutic Antibodies
Dr. Qingyu Cao, Business Development Manager, Algonomics NV, Belgium

17:15-17:30

Discussion

Session Chair:

Dr. Vincent Brichard, Vice President, GlaxoSmithKline Biologicals, Belgium

Co-Chair:

Dr. Dianwen Ju, CEO, MediBiotech, Co. Inc, P.R. China

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Immunotherapy of Cancer: Clinical Development and Perspectives
Dr. Aung Myo, Clinical Development Manager, GlaxoSmithKline Biologicals, Singapore

14:00-14:25

Title: A Rational Approach to Fusion Protein Design and Delivery for Clinical Application against Solid Cancers
Dr. Jeannick Cizeau, Research Director, Viventia Biotechnologies, Canada

14:25-14:50

Title: Development of Catumaxomab, a Trifunctional Antibody for Targeted Treatment of Malignant Ascites
Dr. Diane Seimetz, CSO & Executive Vice President, Fresenius Biotech GmbH，Germany

14:50-15:15

Title: Antibodies in the Treatment of Cancer – Overview and Recent Advances
Dr. Rajesh Shrotriya, Chairman and CEO, Spectrum Pharmaceuticals, Inc., USA

15:15-15:40

Title: Radiolabeled Tumor Necrosis Therapy Monoclonal Antibody for Malignant Cancer Therapy
Dr. Dianwen Ju, CEO, MediBiotech, Co. Inc, P.R. China

15:40-15:50

Coffee Break

15:50-16:10

Title: GTA [Gene-to-Antibody] System for Developing Therapeutic Antibody Drugs
Dr. Xiangbin Wang, Vice-general Manager, Beijing ABT Genetic Engineering Technology Co. Ltd., P.R. China

16:10-16:30

Title: New mAb Identify Fat1 as a Novel Marker for Primitive Human Haemic Stem Cells
Dr. Gordon Burns, Professor, Cancer Research, University of Newcastle, Australia

Session 2-6: Antibodies for Transplantations

Session Chair:

Dr. Alberto L. Horenstein, Senior Researcher, Department of Genetics, Biology and Biochemistry, University of Torino Medical School, Italy

16:30-16:35

Welcome: Session Introduction

16:35-16:55

Title: Identification and Enrichment of Corneal Limbal Cells by Specific Monoclonal Antibodies: A Simple Tool for Improving Transplants
Dr. Alberto L. Horenstein, Senior Researcher, Department of Genetics, Biology and Biochemistry, University of Torino Medical School, Italy

16:55-17:15

Title: Immunosuppressive Autoantibody Induced by Tolerogeneic Liver Transplantation: Its Mode of Action and Drug Application
Dr. Seiji Kawamoto, Associate Professor, Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Japan

17:15-17:35

Title: Role of Alemtuzumab in HLA-mismatched Hematopoietic Stem Cell Transplantation
Dr. Kumi Oshima, Research Associate, Division of Hematology, Saitama Medical Center, Jichi Medical University, Japan

Session Chair:

Dr. Manuel L. Penichet, Assistant Professor, Department of Surgery, University of California, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:25

Title: Targeting the Intracellular Proteome on the Cell Surface: Novel Anti-tumor T-Cell Receptor-Like Therapeutic Antibodies
Dr. Yoram Reiter, Professor, Head, Laboratory of Molecular Immunology, Faculty of Biology, Technion-Israel Institute of Technology, Israel

09:25-09:45

Title: Antibody-mediated Immunoactivation for the Treatment of Cancer and Infectious Diseases
Dr. Manuel L. Penichet, Assistant Professor, Department of Surgery, University of California, USA

09:45-10:05

Title: Management of Advanced Hepatocellular Carcinoma in the Era of Targeted Therapy
Dr. T. Yau, Department of Medicine, Queen Mary Hospital, Hong Kong, P.R. China

10:05-10:25

Title: Screening of Therapeutic Targets for Liver Cancer
Dr. Yutaka Midorikawa, Assistant Professor, Teikyo University, Japan

10:25-10:40

Coffee Break

Session 2-7: Novel Efficient Antibody Delivery

Session Chair:

Dr. Wendy Cai, Senior Pharmacokinetist, Human Genome Sciences, Inc., USA

Co-Chair:

Dr. Maria Bokarewa, Associate Professor, University of Göteborg, Sweden

10:40-10:45

Welcome: Session Introduction

10:45-11:05

Title: Pharmacokinetics of Therapeutic Monoclonal Antibodies
Dr. Wendy Cai, Senior Pharmacokinetist, Human Genome Sciences, Inc., USA

11:05-11:25

Title: Polyhistidine PEGylation of an Antibody Fragment: Novel and Efficient, and Leads to Active Antibody Therapeutics with a Long in Vivo Half-life
Dr. Yuehua Cong, Research Scientist, PolyTherics Ltd., UK

11:25-11:45

Title: Short and Long Term Effects of Anti-CD20 Treatment on B Cell Ontogeny in Bone Marrow of Patients with Rheumatoid Arthritis
Dr. Maria Bokarewa, Associate Professor, University of Göteborg, Sweden

11:45-12:05

Title: Protective Antibody Responses in Malaria Endemic Area and Those of Vaccinees in Phase Ia Clinical Trial of SE36 Malaria Vaccine
Dr. Toshihiro Horii, Professor, Research Institute for Microbial Diseases, Osaka University, Japan

Session Chair:

Dr. Nicolas Fischer, Head of Protein Engineering and Antibody Selection, NovImmune SA, Switzerland

Co-Chair:

Dr. Andrey Tchorbanov, Associate Professor, Department of Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Bulgaria

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: Engineering Antibodies for Targeting Redundant Signaling Pathways in Autoimmunity
Dr. Nicolas Fischer, Head of Protein Engineering and Antibody Selection, NovImmune SA, Switzerland

09:30-09:55

Title: NMR Structures and IgE Epitopes Mapping of Major Allergens from Dust Mite to Prepare Hypoallergens for Immunotherapy
Dr. Yu-Keung MOK Henry, Assistant Professor, Department of Biological Sciences, National University of Singapore, Singapore

09:55-10:20

Title: Generation of Gene-engineered Chimeric DNA Molecules by Recombinant Technologies for Specific Therapy of Autoimmune Diseases
Dr. Andrey Tchorbanov, Associate Professor, Department of Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Bulgaria

10:20-10:35

Coffee Break

10:35-11:00

Title: Efficient Selection of Human McAbs Using Display Technology
Dr. Xiaoling Zhao, Research Fellow, Institute of Health and Enviramental Medicine, P.R. China.

11:00-11:25

Title: T and B cells in Systemic Sclerosis. From Pathogenesis to Treatment
Dr. Lazaros Sakkas, Professor, Thessaly University School of Medicine, Greece, Adjunct Assistant Professor, Temple University School of Medicine, USA

11:25-11:50

Title: Anti-Ab1-42 Monoclonal antibody Mainly Tarteting Oligomer Improves Learning and Memory in SAMP8 Mice
Dr. Ying Zhang, lecturer, College of Life Sciences and Bioengineering, School of Science, Beijing Jiaotong University, China

11:50-12:15

Title: ARG098: A Novel Anti-human Fas IgM Monoclonal Antibody Shows Strong Cytotoxic Effect on Rheumatoid Arthritis Synoviocytes and Infiltrating Lymphocytes
Dr. Masaru Kamishohara, President & CEO, Argenes, Inc., Japan

Session Chair:

Dr. Shan Lu, Professor, Department of Medicine, University of Mass. Medical School, USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Keynote Speech:
Title: Progress in Producing True Human mAb as the Therapeutic Agents for Major Infectious Diseases
Dr. Shan Lu, Professor, Department of Medicine, University of Mass. Medical School, USA

14:00-14:25

Title: Development of CL184 Human Monoclonal Antibody Cocktail for Rabies Post-exposure Prophylaxis, from Preclinical Design to Clinical Evaluation
Dr. Alexander Bakker, Program Director, Antibody Development, Crucell Holland B.V., the Netherlands

14:25-14:50

Title: Soluble Elastin Decreases in the Progress of Atheroma Formation in Human Aorta
Dr. Takashi Akima, Saitama City Hospital, Japan

14:50-15:15

Title: Association of Human Herpesvirus 6 and 8 in Relapsing Remitting Multiple Sclerosis Type during Exacerbation
Dr. Hassan Salama, Consultant Neurologist, Mansoura University, Egypt

15:15-15:25

Coffee Break

Session Chair:

Dr. Steffen Nock, Acting CEO, Arana Therapeutics, USA

Co-Chair:

Dr. Didier Decaudin, Professor, Head, Laboratory of Preclinical Investigation, Translational Research Department, Institute Curie, France

15:25-15:30

Welcome: Session Introduction

15:30-15:55

Keynote Speech:
Title: Strategies for Immunogenicity Assessment of Therapeutic Antibodies
Dr. Philippe Stas, CEO, Algonomics, Belgium

15:55-16:20

Title: Domain Antibody (dAb) Targeting TNF - alpha - from Concept to Clinic
Dr. Steffen Nock, Acting CEO, Arana Therapeutics, USA

16:20-16:45

Title: Novel Mouse Anti-mouse/Human β3 Integrin and GPIbα Monoclonal Antibodies: Development and Characterization of New Reagents for Research in Vascular Biology and Potential Future Anti-thrombotic Therapy
Dr. Heyu Ni, Associate Professor, Physiology and Medicine, University of Toronto, Canada

16:45-17:10

Title: Preclinical Evaluation of New Monoclonal Antibodies in Cancer Therapies: Useful Criteria to the Choice of the Animal's Models
Dr. Didier Decaudin, Professor, Head, Laboratory of Preclinical Investigation, Translational Research Department, Institute Curie, France

17:10-17:35

Title: Animal Model of Guillain–Barre Syndrome
Dr. Nobuhiro Yuki, Niigata National Hospital, Japan

Session Chair:

Dr. Jana Peknicova, Senior Scientist, Institute of Biotechnology, Academy of Sciences of the Czech Republic, Czech Republic

Co-Chair:

Dr. Borut Božič, Vice Dean, University of Ljubljana Faculty of Pharmacy, Slovenia

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Title: Opportunities Presented by Pentameric IgM Towards Successful Two Site Sandwich Quantitative Immunoassays
Dr. M. Abebe, Research Scientist, Environmental Health Science and Research Bureau, Hazard Identification Division, Indoor Air Project, Health Canada, Canada

09:30-09:55

Title: Some Peculiaritis of Thiol Exchange as the Exhibition of Systemic Organism Reaction on the Stress
Dr. N.K. Rodosskaia, Professor, Therapy Department, State Medical Academy Voronezh, Russia

09:55-10:20

Title: Neutralization of the Pharmacological Effects of Cobra and Krait Venoms by Chicken Egg Yolk Antibodies
Dr. A.Michael, Reader and Head, Department of Microbiology, PSG College of Arts and Science, India

10:20-10:35

Coffee Break

10:35-11:00

Title: Posttranslational Oxidative Alterations of Antibody Specificity
Dr. Borut Božič, Vice Dean, University of Ljubljana Faculty of Pharmacy, Slovenia

11:00-11:25

Title: Application of Monoclonal Antibodies against Human Sperm Proteins in Assisted Reproduction
Dr. Jana Peknicova, Senior Scientist, Institute of Biotechnology, Academy of Sciences of the Czech Republic, Czech Republic

11:25-11:50

Title: Principle of technologies used for antibody detection
Dr. Mongia Achour, IMEC Unit Faculty of Sciences, Tunisia

11:50-12:00

Discussion

Session Chair:

Dr. Wen-Quan Zou, Associate Director, National Prion, Disease Pathology Surveillance Center, Case Western Reserve University, USA

Co-Chair:

Dr. Christopher Elliott, Professor and Director, Institute of Agri-Food and Land Use, Queen's University Belfast, UK

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: TUBEX : A Rapid and Simple Test for the Detection of Antibodies or Antigens from Clinical Specimens
Dr. Pak Leong Lim, Chairman, IgGENE Ltd, Hongkong, P.R. China

14:00-14:25

Title: Effect Based Bioanalysis Strategies Applied to Diagnostics for Infectious Diseases and Chemical Contamination Monitoring in Farm Animals
Dr. Christopher Elliott, Professor and Director, Institute of Agri-Food and Land Use, Queen's University Belfast, UK

14:25-14:50

Title: Antibody Diagnostics for Human Prion Diseases
Dr. Wen-Quan Zou, Associate Director, National Prion, Disease Pathology Surveillance Center, Case Western Reserve University, USA

14:50-15:15

Title: Novel Low-cost Assay for the Monitoring of CD4 Counts in HIV-infected Individuals
Dr. Watchara Kasinrerk, Director, Biomedical Technology Research Center, Faculty of Associated Medical Sciences, Chiang Mai University, Thailand

15:15-15:30

Coffee Break

15:30-15:55

Title: Monoclonal Antibodies to Dengue Viral Proteins: Production and Application for Diagnosis of Dengue Virus Iinfection.
Dr. Chunya Puttikhunt, Senior Researcher, National Center for Genetic Engineering and Biotechnology (BIOTEC), Medical Biotechnology Unit, Faculty of Medicine, Siriraj Hospital, Thailand

15:55-16:20

Title:Diagnostic Accuracy of Synthetic Peptides Derived of Ag85a in Pleural Tuberculosis
Dr. Zaida Araujo, Associate Professor, Central University of Venezuela, Venezuela

16:20-16:45

Title: Early and Late Markers for the Detection of Early-onset Neonatal Sepsis
Dr. Lars Bender, Consultant Paediatrician, Aalborg Sygehus Aarhus University Hospital, Denmark

16:45-17:10

Title: Antibodies and Infection in the Era of the Metagenome
Amy Proal, Department of Biology, Georgetown University, USA

17:10-17:30

Discussion

Session Chair:

Dr. Brian Ring, Principal Investigator, Applied Genomics Inc., USA

Co-Chair:

Dr. Shiang Huang, Present, Director and Professor, Center for Stem Cell Research and Application, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, P. R. China

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Keynote Speech:
Title: Translating Gene Expression Classification of Carcinoma into IHC-based Clinical Tools
Dr. Brian Ring, Principal Investigator, Applied Genomics, Inc., USA

09:30-09:55

Title: Clinical Application of Multiplex Flow Cytometry in Leukemia
Dr. Shiang Huang, Present, Director and Professor, Center for Stem Cell Research and Application, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, P. R. China

09:55-10:20

Title: Serum Anti-recoverin Antibody is an Essential Marker and a Causative Factor in Cancer-associated Retinopathy
Dr. Hiroshi Ohguro, Professor and Chairman, Department of Ophthalmology, Sapporo Medical University School of Medicine, Japan

10:20-10:35

Coffee Break

10:35-11:00

Title: Generation of Anti-Met mAb for IHC Diagnosis
Dr. Brian Cao, Deputy Director, Key Laboratory of Antibody Technology of Ministry of Health, Nanjing Medical University, P.R. China

11:00-11:25

Title: Induction of Diagnostic Antibodies against Nucleophosmin with the Aid of Synthetic Peptides
Dr. Olga Volpina,Head of Laboratory, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Russia

11:25-11:50

Title: Anti-nucleophosmin Antibodies for cancer Diagnostics
Dr. Natalia Vladimirova, Senior Researcher, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Russia

11:50-12:00

Discussion

Session Chair:

Dr. Qiang (Ian) Li, President and CSO, ATGCell Inc., Canada

Co-Chair:

Dr. Gang Chen, Director, Cell Technologies, Regeneron Pharmaceuticals, Inc., USA

13:30-13:35

Welcome: Session Introduction

13:35-14:00

Title: Rapid Scale-up: From Transfection to GMP in Less than Six Months
Dr. Igor Fisch, President and CEO, Selexis, Switzerland

14:00-14:25

Title: REEMAC: A Platform for Rapid Antibody Cell Line Generation in CHO Cells
Dr. Qiang (Ian) Li, President and CSO, ATGCell Inc., Canada

14:25-14:50

Title: Cell Line Technologies for Production of Antibodies at Multi-grams/Liter Level
Dr. Gang Chen, Director, Cell Technologies, Regeneron Pharmaceuticals, Inc., USA

14:50-15:15

Title: High-resolution IC/HPLC Columns for Protein/MAb Analysis
Dr. Yuanxue Hou, Senior Staff Chemist, Dionex Corporation, USA

15:15-15:30

Coffee Break

15:30-15:55

Title: Bypassing Conventional Approaches for Rapid Discovery of Rare-event Antibody Producing Cell Lines Using ClonePix FL
Dr. Chris Mann, Senior Application Support Specialist, Genetix Ltd, UK

15:55-16:20

Title: Fast Production of Recombinant Monoclonal Antibodies through Transient Gene Expression
Dr. Guangli Wang, Director, BioProcess Development, GenScript Corporation, USA

16:20-16:45

Title: In Vitro Cultivation of Tick Cells: A System for the Production of Pathogens of Veterinary and Medical Importance
Dr. Lygia Friche Passos, Scientific Staff, Institute for Comparative Tropical Medicine and Parasitology, Ludwig Maximilian University Munich, Germany

16:45-17:10

Title: Cutting Time to Market in mAb Development through Fully Automated Cell Culture Analysis in Cellline- and Upscale Process Development
Dr. Andreas Schneider, Director, global Sales, Innovatis AG, Germany

17:10-17:35

Title: Role of Methylglyoxal Metabolism in the Viability of Lactate Re-utilising CHO Cultures
Dr. E. Keshavarz-Moore, Reader, the Advanced Centre for Biochemical Engineering, Department of Biochemical Engineering, UCL, UK

Session Chair:

Dr. Joe Zhou, Dr. Joe Zhou, CEO, ShineRun BioPharma Co., Ltd, P.R. China

Co-Chair:

Dr. Pei Qi, Principal Scientist, Alder Biopharmaceuticals, USA

09:00-09:05

Welcome: Session Introduction

09:05-09:30

Keynote Speech:
Title: Fully Incorporation of Disposables into Future One-Column mAb Therapeutics Production
Dr. Joe Zhou, CEO, ShineRun BioPharma Co., Ltd, P.R. China

09:30-09:55

Title: Downstream Processing of Monoclonal Antibodies: Trying to Keep the Pace
Dr. Uwe Gottschalk, VP President , Purification Technologies, Sartorius Stedim Biotech, Germany

09:55-10:20

Title: Therapeutic Monoclonal Antibody Stability and Characterization - Photodegradation of a IgG1 Monoclonal Antibody Formulated in High Concentration Liquid Dosage Form
Dr. Pei Qi, Principal Scientist, Alder Biopharmaceuticals, USA

10:20-10:35

Coffee Break

10:35-11:00

Title: Development of Affinity Ligands for Industrial Protein Purification
Dr. Martin Linhult, Senior Engineer, Octapharma AB, Sweden

11:00-11:25

Title: The Role of Large Scale Chromatography in Antibody Manufacturing - Today and Tomorrow
Dr. Lothar Jacob, Marketing Manager, Merck KGaA, Germany

11:25-11:50

Title: Direct Capture of Antibodies from Fermentation Broth Using New Multi-modal High Salt Binding Ion Exchange Materials
Dr. Christian Frech, Professor, Department of Biotechnology, University of Applied Sciences, Germany

11:50-12:15

Title: Fast and Flexible Solution for Modern Biopharmaceutical and Vaccine Manufacturing
Dr. Sven Henrichwark, General Manager, Asia, GE Healthcare, Life Sciences, Singapore